Drugs in MeSH Category Antiperspirants

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Novatech Sa	STERITALC	talc	POWDER;INTRAPLEURAL	205555-002	May 1, 2017		RX	Yes	No
Sciarra Labs	TALC	talc	POWDER;INTRAPLEURAL	021388-001	Dec 15, 2003		RX	Yes	Yes
Sciarra Labs	SCLEROSOL	talc	AEROSOL;INTRAPLEURAL	020587-001	Dec 24, 1997		RX	Yes	Yes
Novatech Sa	STERITALC	talc	POWDER;INTRAPLEURAL	205555-003	May 1, 2017		RX	Yes	Yes

Antiperspirants Market Analysis and Financial Projection

The antiperspirant market is experiencing robust growth driven by innovation, shifting consumer preferences, and regional dynamics. Below is an analysis of its market dynamics and patent landscape, supported by data from clinical studies, industry reports, and patent filings.

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Market Growth and Projections

The global antiperspirant and deodorant market is valued at USD 62.8 billion in 2023, with projections to reach USD 81.9 billion by 2031, growing at a 3.36% CAGR[18]. Alternative estimates suggest a higher growth trajectory, targeting USD 100 billion by 2028 (6.5% CAGR) due to urbanization and hygiene awareness[2]. North America dominates the market, driven by premium product demand, while Asia-Pacific emerges as the fastest-growing region due to rising disposable incomes and urbanization[2][18]. Europe prioritizes sustainability, with 40% of consumers opting for eco-friendly formulations[2].

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Key Consumer Trends

• Natural and Aluminum-Free Products: Demand for aluminum-free antiperspirants surged by 22% in 2025, driven by health concerns and clean beauty movements[16].
• Advanced Formulations: Brands like Degree introduced 72-hour sweat-control microtechnology, reducing reapplication needs[16].
• Sustainability: Over 60% of European consumers favor recyclable packaging, pushing brands to adopt biodegradable materials[2][18].

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Patent Innovations

Recent patents highlight breakthroughs in formulation safety and efficacy:	Patent Focus	Innovation	Example
Aluminum Alternatives	Chitosan-based antiperspirants reducing sweat without aluminum[5][10]	Patent 11,154,485: Blocks sweat glands using chitosan[5]
Fragrance Delivery	Inorganic-shell capsules preventing perfume leakage[17]	Patent 11,938,349: Enhanced perfume stability in antiperspirants[17]
Suspension Stability	Hydrophobic clay minerals and rice starch improving product texture[5][13]	Patent 11,103,426: Non-streaking, long-lasting formulas[5]

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Challenges and Controversies

• Aluminum Safety: While systemic absorption is low, debates persist about links to Alzheimer’s and breast cancer[10].
• Regulatory Compliance: The FDA’s 2021 monograph mandates safety evaluations for OTC antiperspirants[7].
• Environmental Impact: Plastic packaging accounts for 30% of landfill waste, prompting shifts to refillable containers[2][8].

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Regional Dynamics

• North America: Premium products like clinical-strength antiperspirants dominate, with 85% efficacy in sweat reduction[1][9].
• Asia-Pacific: Growth centers on budget-friendly options, with 15% annual sales increases in India and China[2].
• Europe: Aluminum-free products claim 35% market share, driven by strict EU regulations on fragrances and preservatives[6][18].

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Future Outlook

By 2030, AI-driven personalization and probiotic-infused formulas targeting axillary microbiota imbalances will reshape the industry[11]. Meanwhile, patent filings for aluminum-zirconium complexes and pH-balanced gels signal a focus on skin compatibility[13][16]. The market’s evolution hinges on balancing efficacy, safety, and sustainability, with USD 1.2 billion invested in R&D in 2025 alone[14].

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"Over-the-counter clinical-strength antiperspirants are now a viable alternative to prescription aluminum chloride, offering comparable efficacy with reduced irritation." – Clinical Study Summary[1].

This analysis highlights a sector poised for growth but constrained by regulatory and environmental pressures, with innovation centered on safety and sustainability.

References

1. https://pubmed.ncbi.nlm.nih.gov/22385032/
2. https://reads.alibaba.com/antiperspirant-deodorant-understanding-its-benefits-and-choices/
3. https://www.cognitivemarketresearch.com/antiperspirant-and-deodorant-market-report
4. https://www.cognitivemarketresearch.com/deodorant-antiperspirant-market-report
5. https://patents.justia.com/patents-by-us-classification/424/65
6. https://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_102.pdf
7. https://pubmed.ncbi.nlm.nih.gov/12795305/
8. https://www.coherentmarketinsights.com/market-insight/deodorant-and-antiperspirant-market-4690
9. https://pubmed.ncbi.nlm.nih.gov/30249082/
10. https://pubmed.ncbi.nlm.nih.gov/32248967/
11. https://pubmed.ncbi.nlm.nih.gov/33644863/
12. https://www.science.gov/topicpages/g/gel+combination+topically
13. https://patents.google.com/patent/US5135741A/en
14. https://www.marketresearchintellect.com/blog/the-battle-against-sweat-innovations-shaping-the-antiperspirant-market/
15. https://patents.google.com/patent/US20110256082A1/en
16. https://reads.alibaba.com/understanding-deodorant-antiperspirant-a-comprehensive-guide/
17. https://patents.justia.com/patent/11938349
18. https://www.snsinsider.com/reports/antiperspirants-and-deodorants-market-1008

Last updated: 2025-03-24