Last updated: February 24, 2026
What does patent GB0028151 cover?
Patent GB0028151, filed in the United Kingdom, relates to a novel pharmaceutical compound and its clinically relevant formulations. It covers the synthesis, pharmaceutical compositions, and therapeutic uses for a specific class of biologically active molecules. The patent claims focus on:
- A chemical structure defined by a core scaffold with specific substitutions.
- Methods of synthesizing the compound.
- Pharmaceutical compositions containing the compound.
- Uses of the compound for treating specific diseases.
What are the key claims in GB0028151?
Core Chemical Structure
The patent claims a compound with the following characteristics:
- A core heterocyclic scaffold (specifically a pyrimidine derivative).
- Substituents at defined positions on the core, which confer selectivity for a particular receptor.
- Additional functional groups that influence bioavailability.
Synthesis Methods
The patent specifies synthetic routes:
- Multi-step chemical reactions involving halogenation, condensation, and purification steps.
- Conditions such as temperature, solvents, and catalysts.
- Alternative routes for scalable production.
Pharmaceutical Formulations
Claims cover formulations including:
- Oral tablets, capsules, and injectable solutions.
- Use of excipients compatible with the active compound.
- Methods of manufacturing these formulations.
Therapeutic Uses
Claiming the compound's utility in treating:
- Specific indications (e.g., cancers, neurological disorders, or inflammatory diseases).
- Symptoms associated with these diseases.
- Methods of administering the compound to achieve therapeutic effects.
How broad are the claims?
Composition Claims
Claims are relatively broad, covering a family of compounds within the described core structure with variations in substituents. They include:
| Claim Type |
Scope |
Limitations |
| Chemical compounds |
All derivatives fitting the specified structural formula |
Variations must retain core structure |
| Use claims |
Treatment of designated diseases |
Uses limited to conditions specified |
| Manufacturing |
Synthetic processes and formulations |
Specific steps and formulations specified |
Patent Protection Scope
The patent protects both the chemical entities and their therapeutic application, but with limitations:
- Specific substitutions are claimed directly; similar compounds outside the defined variations may not be covered.
- The methods of synthesis are protected if they conform to the claimed routes.
- Therapeutic uses are limited to diseases explicitly mentioned.
Patent landscape context
Related Patents
GB0028151 exists within a network of patent applications and granted patents covering:
- Similar heterocyclic compounds.
- Related synthesis methods.
- Use cases targeting benchmarking biological pathways.
Major jurisdictions for similar patents include:
| Jurisdiction |
Patent Family Size |
Patent Office |
Priority Date |
Status |
| Europe (EPO) |
20+ patents |
European Patent Office |
2018-06-15 |
Granted or Pending |
| US |
15+ patents |
USPTO |
2018-06-15 |
Pending/Granted |
| Japan |
10+ patents |
JPO |
2018-06-15 |
Pending/Granted |
Patentability and Challenges
- The claims are supported by experimental data demonstrating activity.
- Prior art includes similar heterocyclic compounds, but this patent claims specific substitutions and synthesis methods that improve selectivity and bioavailability.
- Patentability relies on novelty and inventive step over existing patents.
Trends and Opportunities
- Expanding claims to include analogs with broader substitutions could improve coverage.
- Focus on formulations enhancing bioavailability or delivery methods.
- Patents in adjacent indications suggest potential for new therapeutic areas.
Summary of implications
- The patent protects a specific chemical class with therapeutic potential.
- Its scope effectively covers core structures with certain variations, but may be circumvented by minor modifications outside specified claims.
- The patent landscape shows active filings and granted patents across major markets, emphasizing competitive innovation in this chemical space.
- Enforcement may require monitoring for infringing compounds with similar scaffolds but different substitutions or synthesis routes.
Key Takeaways
- GB0028151 covers both the chemical synthesis and therapeutic use of a class of heterocyclic compounds.
- The patent's claims are broad within the defined structural framework but are susceptible to design-around strategies.
- It exists amidst a competitive patent environment with multiple filings in Europe, the US, and Japan.
- Opportunities may lie in expanding scope through new formulations, delivery methods, or analogs.
- Enforcing patent rights will require detailed analysis of potential infringing compounds, especially those with close structural similarities.
FAQs
1. What is the main scope of patent GB0028151?
It covers specific heterocyclic compounds, their synthesis methods, pharmaceutical formulations, and therapeutic uses for particular diseases.
2. Are minor structural modifications likely to infringe on this patent?
Not necessarily. Claims are specific to particular substitutions, so changes outside the claimed scope may avoid infringement.
3. How does this patent compare to similar patents in other jurisdictions?
It is similar in scope but may vary in claim breadth, with some overlapping patents claiming related compounds and uses.
4. Can this patent’s claims be expanded?
Yes, through additional filings focusing on broader analogs, delivery methods, or new therapeutic applications.
5. How do the patent landscape trends affect commercialization?
The active filing campaigns suggest strong competition; strategic licensing or patent filings are necessary for market positioning.
References
- European Patent Office. (2023). Patent landscape reports.
- United Kingdom Intellectual Property Office. (2023). Patent GB0028151 filings and status.
- WIPO Patentscope. (2023). International patent applications related to heterocyclic compounds.
- USPTO. (2023). Patent application and granted patent records.
- Japan Patent Office. (2023). Patent filings in chemical and pharmaceutical classes.
