Last Updated: May 11, 2026

Piperonyl butoxide; pyrethrins - Generic Drug Details


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What are the generic sources for piperonyl butoxide; pyrethrins and what is the scope of patent protection?

Piperonyl butoxide; pyrethrins is the generic ingredient in one branded drug marketed by Bayer Healthcare Llc and is included in one NDA. Additional information is available in the individual branded drug profile pages.

Summary for piperonyl butoxide; pyrethrins
US Patents:0
Tradenames:1
Applicants:1
NDAs:1
Clinical Trials: 1
DailyMed Link:piperonyl butoxide; pyrethrins at DailyMed
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US Patents and Regulatory Information for piperonyl butoxide; pyrethrins

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Bayer Healthcare Llc RID MOUSSE piperonyl butoxide; pyrethrins AEROSOL;TOPICAL 021043-001 Mar 7, 2000 DISCN No No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Market Dynamics and Financial Trajectory for Piperonyl Butoxide and Pyrethrins

Last updated: February 17, 2026

What Are Piperonyl Butoxide and Pyrethrins?

Piperonyl butoxide (PBO) is a chemical synergist used to enhance the potency of pyrethroid insecticides. Pyrethrins are natural insecticides derived from Chrysanthemum flowers, primarily used in pest control. Both compounds feature in products for agriculture, household insecticides, and public health applications.

What Is the Market Size and Growth for Piperonyl Butoxide and Pyrethrins?

The combined global market for these agents was valued at approximately USD 1.2 billion in 2021. It is projected to increase at a compound annual growth rate (CAGR) of 4.5% from 2022 through 2027, reaching USD 1.66 billion.

Key Drivers

  • Rising demand for pest control in agriculture and households due to increased awareness of vector-borne diseases.
  • Growth of the insecticide market, especially in developing regions.
  • Stringent regulations favoring natural products, boosting demand for pyrethrins.

Market Segments

Segment 2021 Value (USD million) CAGR (2022-2027) Notes
Household Pest Control 530 4.3% Major end-user; shift towards eco-friendly products
Agriculture 420 4.7% Used in crop protection, especially in Asia-Pacific
Commercial & Public Health 250 4.9% Malaria vector control and public health programs

How do Regulatory Policies Affect Market Dynamics?

Increased regulation on synthetic insecticides has driven demand towards natural-based products like pyrethrins. Conversely, restrictions on certain formulations containing piperonyl butoxide have created supply constraints, affecting pricing and product availability.

Regulations by Region

  • United States: EPA classifies pyrethrins as minimum risk pesticides; registration delays impact formulations.
  • European Union: Phased restrictions on PBO in some formulations due to toxicity concerns.
  • Asia-Pacific: Limited regulation; market expansion driven by emerging economies.

What Are the Key Players and Trends?

Major manufacturers include Sumitomo Chemical, FMC Corporation, and Buhler. These companies are investing in sustainable extraction methods for pyrethrins and improving formulation efficiency.

Innovation Trends

  • Development of biodegradable formulations.
  • Enhancement of safety profiles through novel synergists.
  • Expansion into complementary products targeting vector-borne diseases.

What Are the Financial Trajectories and Investment Opportunities?

Profit margins for producers of PBO and pyrethrins range from 12% to 18%, influenced by raw material costs and regulatory pressures. Revenue growth has been steady; however, price volatility exists due to raw material supply constraints.

Investment Considerations

  • Demand growth in emerging markets favors supply chain expansion.
  • Regulatory risks necessitate R&D investments in safer alternatives.
  • Mergers and acquisitions are increasing as companies seek a competitive edge.

What Is the Supply Chain Landscape?

Supply chains depend heavily on raw material sourcing, especially Chrysanthemum flower cultivation for pyrethrins and petrochemical sources for PBO. Climate conditions and geopolitical factors impact raw material availability.

How Do Future Outlooks Look?

Anticipate continued demand growth driven by pest control needs, especially in malaria-endemic regions. Regulatory shifts toward natural and safer chemical options may limit synthetic insecticide use, favoring pyrethrins. Market expansion into new regions is probable as awareness and infrastructure improve.

Key Takeaways

  • The USD 1.2 billion market is expected to grow at 4.5% CAGR through 2027.
  • Regulatory trends favor natural products, but synthetic synergists like PBO face restrictions.
  • Consumer preference for eco-friendly pest control boosts pyrethrins demand.
  • Supply chain vulnerabilities relate to raw material sourcing and geopolitics.
  • Innovation focuses on biodegradable, safer formulations and extraction methods.

FAQs

1. How does regulatory pressure impact the production and sale of these chemicals? Regulatory agencies impose restrictions based on toxicity profiles, affecting formulations and leading to supply constraints, especially in regions like the EU.

2. Are there substitutes for pyrethrins and piperonyl butoxide? Synthetic alternatives exist but face similar regulatory and safety hurdles. Natural compounds like neem oil are emerging substitutes but have different efficacy profiles.

3. Which regions drive the highest demand for these compounds? Asia-Pacific leads in demand, particularly in agriculture and public health. North America and Europe have stable markets with stricter regulations.

4. What role does innovation play in the market? Innovation improves formulation safety, efficacy, and environmental impact, influencing regulatory approval and consumer acceptance.

5. What are potential risks for investors? Key risks include regulatory restrictions, raw material supply disruptions, and market shifts toward alternative pest control methods.


Sources

[1] MarketsandMarkets, "Insecticides Market by Type," 2022.
[2] U.S. Environmental Protection Agency, "Pyrethrins and Pyrethroids," 2022.
[3] European Chemicals Agency, "Piperonyl Butoxide Authorization," 2021.
[4] Mordor Intelligence, "Pest Control Market - Trends and Forecasts," 2022.

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