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Plerixafor - Generic Drug Details

What are the generic drug sources for plerixafor and what is the scope of plerixafor freedom to operate?

Plerixafor is the generic ingredient in one branded drug marketed by Genzyme and is included in one NDA. There are three patents protecting this compound and one Paragraph IV challenge. Additional information is available in the individual branded drug profile pages.

There are seven drug master file entries for plerixafor. One supplier is listed for this compound.

Summary for plerixafor

US Patents:	3
Tradenames:	1
Applicants:	1
NDAs:	1
Drug Master File Entries:	7
Suppliers / Packagers:	1
Bulk Api Vendors:	77
Clinical Trials:	124
Patent Applications:	1,696
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for plerixafor
DailyMed Link:	plerixafor at DailyMed

Pharmacology for plerixafor

Drug Class	Hematopoietic Stem Cell Mobilizer
Physiological Effect	Increased Hematopoietic Stem Cell Mobilization

Synonyms for plerixafor

078P461
1-({4-[(1,4,8,11-tetraazacyclotetradecan-1-yl)methyl]phenyl}methyl)-1,4,8,11-tetraazacyclotetradecane
1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane
1-{[4-(1,4,8,11-tetraazacyclotetradecan-1-ylmethyl)phenyl]methyl}-1,4,8,11-tetraazacyclotetradecane
1,1'-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane
1,1'-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane]
1,1'-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane] & Galanthus nivalis agglutinin (GNA)
1,1'-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane] & Hippeastrum hybrid agglutinin( HHA)
1,1'-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane] & Hippeastrum hybrid agglutinin(HHA)
1,1'-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-tetraaza-cyclotetradecane}
1,1''''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-tetraaza-cyclotetradecane}
1,1'[1,4-phenylene-bis-(methylene)]-bis-1,4,8,11-tetraazacyclotetradecane
1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene
1,4,8,11-tetraazacyclotetradecanyl[4-(1,4,8,11-tetraazacyclotetradecanylmethyl)phenyl]methane
1,4,8,11-tetraazacyclotetradecanyl[4-(1,4,8,11-tetraazacyclotetradecanylmethyl)phenyl]methane(8HBr.2H2O)
11-{4-[4,8, 11-1,4,8,11tetraaza-cyclotetradec-1-ylmethyl]-benzyl}-1,4,8,11tetraaza-cyclotetradecane-1,4,8-tricarboxylic acid tri-tert-butyl ester
11''''-xylyl bis-1,4,8,11-tetraazacyclotetradecane
110078-46-1
155148-31-5
3B1-000393
4CA-1029
A25446
A809618
AB0009909
AB01566900_01
AB1008451
AC-26837
AC1L22ET
AJ-81365
AK-41732
AKOS005266706
Amd 3100
AMD-3100
AMD3100
AMD3100 octahydrochloride
AN-436
ANW-73610
AOB5591
BC623053
BCPP000104
BDBM50035696
bicyclam JM-2987
BRD-K33240821-367-01-8
C28H54N8
CHEBI:125354
CHEMBL18442
CS-0451
CTK8C4952
D08971
D0L5RW
DB06809
FT-0660392
GNA & AMD-3100
GTPL844
HE070541
HE295036
HHA & AMD-3100
HY-10046
I14-9461
J-503718
JM 2987
JM 3100
JM 3100, AMD3100
JM-3100
JM3100
KS-00000OBY
L000104
LS-187299
MFCD05662218
MolPort-009-019-417
Mozobil
Mozobil (TN)
NCGC00165722-01
NCGC00165722-02
plerixafor (amd3100)
Plerixafor (INN/USAN)
Plerixafor (JAN/USAN/INN)
Plerixafor 8HCl
Plerixafor hcl
Plerixafor hydrochloride
Plerixafor(AMD3100)
RL00426
S-7677
s8030
S915P5499N
SC-21932
SCHEMBL19038
SDZ SID 791
SID791
SR-01000941593
SR-01000941593-1
ST2414835
TC-162355
UNII-S915P5499N
YIQPUIGJQJDJOS-UHFFFAOYSA-N
Z2196779619
ZINC22443609

US Patents and Regulatory Information for plerixafor

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Glossary

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Genzyme	MOZOBIL	plerixafor	SOLUTION;SUBCUTANEOUS	022311-001	Dec 15, 2008		RX	Yes	Yes	➤ Sign Up	➤ Sign Up	Y			➤ Sign Up
Genzyme	MOZOBIL	plerixafor	SOLUTION;SUBCUTANEOUS	022311-001	Dec 15, 2008		RX	Yes	Yes	➤ Sign Up	➤ Sign Up				➤ Sign Up
Genzyme	MOZOBIL	plerixafor	SOLUTION;SUBCUTANEOUS	022311-001	Dec 15, 2008		RX	Yes	Yes	➤ Sign Up	➤ Sign Up				➤ Sign Up
Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration

Expired US Patents for plerixafor

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	Patent No.	Patent Expiration
Genzyme	MOZOBIL	plerixafor	SOLUTION;SUBCUTANEOUS	022311-001	Dec 15, 2008	➤ Sign Up	➤ Sign Up
Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	Patent No.	Patent Expiration

International Patents for plerixafor

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Country	Document Number	Estimated Expiration
Portugal	1411918	➤ Sign Up
Finland	942849	➤ Sign Up
World Intellectual Property Organization (WIPO)	2005000333	➤ Sign Up
Country	Document Number	Estimated Expiration

Supplementary Protection Certificates for plerixafor

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Supplementary Protection Certificate	SPC Country	SPC Expiration	SPC Description
C/GB12/031	United Kingdom	➤ Sign Up	PRODUCT NAME: PLERIXAFOR OPTIONALLY IN THE FORM OF A PHARMACEUTICALLY ACCEPTABLE SALT OR METAL COMPLEX THEREOF; REGISTERED: UK EU/1/09/537/001 20090804
2009 00052	Denmark	➤ Sign Up
0537	Netherlands	➤ Sign Up	PRODUCT NAME: PLERIXAFOR, DESGEWENST IN DE VORM VAN EEN FARMACEUTISCH AANVAARDBAAR ZOUT OF METAALCOMPLEX; REGISTRATION NO/DATE: EU/1/09/537/001 20090804
Supplementary Protection Certificate	SPC Country	SPC Expiration	SPC Description