You're using a free limited version of DrugPatentWatch: Upgrade for Complete Access

Last Updated: March 24, 2025

Drugs Containing Excipient (Inactive Ingredient) SODIUM BICARBONATE


✉ Email this page to a colleague

« Back to Dashboard


Branded drugs containing SODIUM BICARBONATE excipient, and estimated key patent expiration / generic entry dates

Generic drugs containing SODIUM BICARBONATE excipient

Market Dynamics and Financial Trajectory for Pharmaceutical Grade Sodium Bicarbonate

Introduction

Pharmaceutical grade sodium bicarbonate, commonly known as baking soda, is a crucial component in the pharmaceutical industry. Its versatile applications and growing demand make it an important market to analyze.

Market Size and Forecast

The global pharma grade sodium bicarbonate market was valued at USD 250.89 million in 2022 and is projected to grow to USD 335.26 million by 2030, with a compound annual growth rate (CAGR) of approximately 3.69% between 2023 and 2030[1].

Key Drivers of Growth

Several factors are driving the growth of the pharma grade sodium bicarbonate market:

Rising Demand for Premium Pharmaceutical Components

The increasing demand for high-quality pharmaceutical ingredients is a primary driver. Sodium bicarbonate is widely used as an active pharmaceutical ingredient (API) and as an excipient in various drug formulations[1].

Growing Geriatric Population

The global rise in the geriatric population has led to an increased consumption of sodium-based medications, further fueling the market growth[1].

Diverse Applications

Sodium bicarbonate is used in treating metabolic acidosis, hemodialysis, cardiac arrest, and severe primary lactic acidosis. It is also used in antacids, as a urinary alkalizer, and in the treatment of certain drug intoxications[2][5].

Market Segmentation

The pharma grade sodium bicarbonate market can be segmented based on application and grade:

By Application

  • Active Pharmaceutical Ingredient (API): Expected to dominate the market due to its increasing use in producing effervescent tablets and enhancing drug capabilities.
  • Excipients: Used for effervescence and tablet disintegration.
  • Toothpaste: Commonly used as an abrasive and pH buffer.
  • Hemodialysis: Increasing application in this area is projected to drive market growth.
  • Antacids: Used to neutralize stomach acid and provide relief from hyperacidity symptoms[1][4].

By Grade

  • Fine Grade: Used in applications requiring finer particle sizes.
  • Coarse Grade: Used in applications where larger particle sizes are necessary[1].

Regional Analysis

The North American region is anticipated to dominate the pharma grade sodium bicarbonate market due to the robust development of the pharmaceutical sector and high adoption rates of active pharmaceutical ingredients and excipients in this region[1].

Key Players

Major players in the global pharma grade sodium bicarbonate market include:

  • Novacarb
  • CIECH
  • Tronox Alkali Corporation
  • Tosoh Corporation
  • Jost Chemical Company
  • Tata Chemicals
  • Natural Soda
  • Church and Dwight
  • GHCL Ltd.
  • Solvay[1].

Mechanism of Action and Pharmacology

Sodium bicarbonate acts as a systemic alkalizer, increasing plasma bicarbonate levels, buffering excess hydrogen ions, and raising blood pH to reverse acidosis. It also functions as a urinary alkalizer, increasing the excretion of free bicarbonate ions in the urine, which helps in the dissolution of uric acid stones and reduces the nephrotoxicity of blood pigments[2][5].

Economic Impact

The growth of the pharma grade sodium bicarbonate market is not only driven by pharmaceutical applications but also influenced by broader economic trends. The increasing demand for convenience foods, for instance, indirectly supports the market as sodium bicarbonate is used in food products as well[3].

Challenges and Opportunities

While the market is poised for growth, there are challenges to consider:

  • Regulatory Compliance: Strict regulations in the pharmaceutical industry can impact the production and use of pharma grade sodium bicarbonate.
  • Competition: The presence of multiple players in the market can lead to competitive pricing and market share battles.
  • Innovation: Opportunities exist for innovating new applications and formulations that can further enhance the market growth[1][4].

Conclusion

The pharma grade sodium bicarbonate market is on a steady growth trajectory, driven by its diverse applications in the pharmaceutical industry, the growing geriatric population, and the increasing demand for premium pharmaceutical components. With a projected CAGR of 3.69% between 2023 and 2030, this market is set to continue its expansion, offering significant opportunities for key players and new entrants alike.

Key Takeaways

  • The global pharma grade sodium bicarbonate market is expected to grow from USD 250.89 million in 2022 to USD 335.26 million by 2030.
  • The API segment is expected to dominate the market due to its increasing use in drug formulations.
  • North America is anticipated to be the leading region in the market.
  • Key applications include treating metabolic acidosis, hemodialysis, and as an excipient in various drug formulations.
  • Major players such as Novacarb, CIECH, and Tronox Alkali Corporation are significant contributors to the market.

FAQs

Q: What is the primary use of pharma grade sodium bicarbonate in the pharmaceutical industry? A: Pharma grade sodium bicarbonate is primarily used as an active pharmaceutical ingredient (API) and as an excipient in various drug formulations, including treating metabolic acidosis and hemodialysis[1][2].

Q: Which region is expected to dominate the pharma grade sodium bicarbonate market? A: The North American region is anticipated to dominate the market due to the robust development of the pharmaceutical sector and high adoption rates of active pharmaceutical ingredients and excipients[1].

Q: What is the projected CAGR of the pharma grade sodium bicarbonate market between 2023 and 2030? A: The market is expected to grow at a CAGR of approximately 3.69% between 2023 and 2030[1].

Q: How does sodium bicarbonate act in the body? A: Sodium bicarbonate acts as a systemic alkalizer, increasing plasma bicarbonate levels, buffering excess hydrogen ions, and raising blood pH to reverse acidosis. It also functions as a urinary alkalizer[2][5].

Q: What are some of the key players in the global pharma grade sodium bicarbonate market? A: Major players include Novacarb, CIECH, Tronox Alkali Corporation, Tosoh Corporation, Jost Chemical Company, Tata Chemicals, and others[1].

Sources

  1. Zion Market Research - Pharma Grade Sodium Bicarbonate Market Size, Share, Trends ...
  2. DrugBank - Sodium bicarbonate: Uses, Interactions, Mechanism of Action
  3. SkyQuest - Sodium Bicarbonate Market Size and Forecast to 2030
  4. AH Performance - Pharmaceutical Grade Sodium Bicarbonate – ARM & HAMMER™
  5. Pfizer - Sodium Bicarbonate Injection USP, 8.4%

More… ↓

⤷  Try for Free

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.