Drugs Containing Excipient (Inactive Ingredient) D&C RED NO. 27 ALUMINUM LAKE

Branded drugs containing D&C RED NO. 27 ALUMINUM LAKE excipient, and estimated key patent expiration / generic entry dates

Company	Tradename	Ingredient	NDC	Excipient	Potential Generic Entry
Neolpharma Inc	LEVO-T	levothyroxine sodium	55466-114	D&C RED NO. 27 ALUMINUM LAKE

Generic drugs containing D&C RED NO. 27 ALUMINUM LAKE excipient

Company	Ingredient	NDC	Excipient
NCS HealthCare of KY LLC dba Vangard Labs	haloperidol	0615-8355	D&C RED NO. 27 ALUMINUM LAKE
Upsher-smith Laboratories LLC	amitriptyline hydrochloride	0832-1220	D&C RED NO. 27 ALUMINUM LAKE
Major Pharmaceuticals	enalapril maleate	0904-7309	D&C RED NO. 27 ALUMINUM LAKE

Market overview and financial trajectory for D&C Red No. 27 Aluminum Lake

Last updated: February 10, 2026

Market Size and Growth Drivers

D&C Red No. 27 Aluminum Lake is a synthetic dye used primarily in pharmaceutical, food, and cosmetic applications. The pharmaceutical segment accounts for a significant share, driven by demand for coloring agents in tablets and capsules.

Global demand for pharmaceutical excipients is projected to grow at a CAGR of approximately 6.5% from 2023 to 2030, with coloring agents like D&C Red No. 27 Aluminum Lake contributing to this expansion. The compound's applications in formulating visually appealing medicines for pediatric and geriatric populations sustain its relevance.

Manufacturing and Supply Chain

D&C Red No. 27 Aluminum Lake is produced through a multistep synthesis involving the polymerization of dye precursors and aluminum hydroxide complexation. The key players include manufacturers in North America, Europe, and Asia, with China and India accounting for roughly 45% of global output.

Raw material prices, especially those of dye precursors and aluminum salts, directly influence production costs. Supply chain disruptions—such as shortages of raw materials or logistical constraints—can impact availability and pricing.

Market Dynamics

• Regulatory Environment: U.S. FDA’s approval of D&C Red No. 27 Aluminum Lake as a color additive in pharmaceutical products sustains demand. However, increased regulatory scrutiny for synthetic dyes in food and pharmaceuticals could restrict or delay approvals in certain jurisdictions.

• Consumer Preferences: Growing consumer awareness regarding synthetic dyes prompts some pharmaceutical firms to explore natural alternatives. While D&C Red No. 27 Aluminum Lake remains the industry standard, shifts toward natural colorants could temper growth.

• Competitive Landscape: About ten major manufacturers dominate the market, including Jungbunzlauer, Spectrum Chemical, and others. These firms focus on quality assurance, regulatory compliance, and cost leadership.

Financial Trajectory Projections

• Revenue: Estimated global revenues for D&C Red No. 27 Aluminum Lake are approximately $150 million in 2023. A compound annual growth rate (CAGR) of 4-6% is forecasted over the next five years, driven by pharmaceutical formulation demand.

• Pricing Trends: Prices are influenced by raw material costs, regulatory costs, and competition. Currently, prices range from $3.50 to $5.00 per gram. Expected to remain relatively stable with minor fluctuations owing to raw material cost volatility.

• Profitability: Profit margins for manufacturers range from 15% to 25%, inversely related to raw material prices and regulatory costs. Industry consolidation may improve margins through economies of scale.

Risks and Opportunities

• Risks include regulatory restrictions, shifts toward natural dyes, and raw material price volatility.
• Opportunities stem from expanding pharmaceutical markets in emerging economies and potential innovation in dye formulations that meet stricter safety standards.

---

Key Takeaways

• D&C Red No. 27 Aluminum Lake has a stable market driven by pharmaceutical and cosmetic applications.
• The global market is projected to grow modestly, with revenues near $150 million in 2023.
• Supply chain and raw material costs impact pricing and profitability.
• Regulatory and consumer trends favoring natural dyes could influence future demand.
• Major manufacturers maintain market dominance, with growth opportunities in emerging markets.

---

FAQs

1. What are the main applications of D&C Red No. 27 Aluminum Lake?

   • It is primarily used as a coloring agent in oral pharmaceutical formulations, including tablets and capsules, and also in cosmetics and food products.

2. How does regulation affect the market for D&C Red No. 27 Aluminum Lake?

   • Regulatory approval by agencies like the FDA sustains market access. Stricter regulations or bans on synthetic dyes in certain countries could restrict its use.

3. What factors influence the raw material prices for manufacturing D&C Red No. 27 Aluminum Lake?

   • Prices depend on the cost of dye precursor chemicals and aluminum salts, along with logistics and raw material supply stability.

4. Who are the leading producers of D&C Red No. 27 Aluminum Lake?

   • Major producers include Jungbunzlauer, Spectrum Chemical, and other specialty chemical firms based in North America, Europe, and Asia.

5. What future trends could impact the demand for D&C Red No. 27 Aluminum Lake?

   • Increased regulation, rising consumer demand for natural dyes, and innovation in pharmaceutical formulation could influence demand patterns.

---

Sources:

[1] MarketsandMarkets, "Pharmaceutical Excipients Market," 2023.
[2] Grand View Research, "Color Additives Market," 2022.
[3] U.S. FDA, "Color Additive Status List," 2023.
[4] Industry Reports, "Synthetic Dyes Production & Global Supply Chain," 2022.