List of Excipients in API fluoxetine
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Excipients in NDA-approved (novel) drugs containing fluoxetine
| Company | Tradename | Ingredient | NDC | Excipient | Potential Generic Entry |
|---|---|---|---|---|---|
| TWi Pharmaceuticals Inc | FLUOXETINE HCL | fluoxetine hcl | 24979-255 | CELLULOSE, MICROCRYSTALLINE | |
| TWi Pharmaceuticals Inc | FLUOXETINE HCL | fluoxetine hcl | 24979-255 | GLYCERIN | |
| TWi Pharmaceuticals Inc | FLUOXETINE HCL | fluoxetine hcl | 24979-255 | HYPROMELLOSE | |
| TWi Pharmaceuticals Inc | FLUOXETINE HCL | fluoxetine hcl | 24979-255 | MAGNESIUM STEARATE | |
| TWi Pharmaceuticals Inc | FLUOXETINE HCL | fluoxetine hcl | 24979-255 | MANNITOL | |
| TWi Pharmaceuticals Inc | FLUOXETINE HCL | fluoxetine hcl | 24979-255 | POLYSORBATE 80 | |
| TWi Pharmaceuticals Inc | FLUOXETINE HCL | fluoxetine hcl | 24979-255 | POVIDONE | |
| >Company | >Tradename | >Ingredient | >NDC | >Excipient | >Potential Generic Entry |
Excipients in ANDA-approved (generic) drugs containing fluoxetine
Detailed excipient profiles for fluoxetine
Excipient focus: ALCOHOL
fluoxetine drug variants containing ALCOHOL
fluoxetine drug variants not containing ALCOHOL
Excipient focus: ALUMINUM OXIDE
fluoxetine drug variants containing ALUMINUM OXIDE
fluoxetine drug variants not containing ALUMINUM OXIDE
Excipient focus: AMMONIA
fluoxetine drug variants containing AMMONIA
fluoxetine drug variants not containing AMMONIA
Excipient focus: ASCORBIC ACID
fluoxetine drug variants containing ASCORBIC ACID
| Company | Ingredient | NDC |
|---|---|---|
| ScieGen Pharmaceuticals Inc | fluoxetine hydrochloride | 50228-638 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing ASCORBIC ACID
Excipient focus: BENZOIC ACID
fluoxetine drug variants containing BENZOIC ACID
fluoxetine drug variants not containing BENZOIC ACID
Excipient focus: BENZYL ALCOHOL
fluoxetine drug variants containing BENZYL ALCOHOL
| Company | Ingredient | NDC |
|---|---|---|
| Dista Products Company | fluoxetine hydrochloride | 0777-3104 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing BENZYL ALCOHOL
Excipient focus: BUTYL ALCOHOL
fluoxetine drug variants containing BUTYL ALCOHOL
fluoxetine drug variants not containing BUTYL ALCOHOL
Excipient focus: BUTYLPARABEN
fluoxetine drug variants containing BUTYLPARABEN
| Company | Ingredient | NDC |
|---|---|---|
| Dista Products Company | fluoxetine hydrochloride | 0777-3104 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing BUTYLPARABEN
Excipient focus: CARBOXYMETHYLCELLULOSE
fluoxetine drug variants containing CARBOXYMETHYLCELLULOSE
| Company | Ingredient | NDC |
|---|---|---|
| Dista Products Company | fluoxetine hydrochloride | 0777-3104 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing CARBOXYMETHYLCELLULOSE
Excipient focus: CELLULOSE, MICROCRYSTALLINE
fluoxetine drug variants containing CELLULOSE, MICROCRYSTALLINE
fluoxetine drug variants not containing CELLULOSE, MICROCRYSTALLINE
Excipient focus: COLLOIDAL SILICON DIOXIDE
fluoxetine drug variants containing COLLOIDAL SILICON DIOXIDE
| Company | Ingredient | NDC |
|---|---|---|
| NCS HealthCare of KY Inc dba Vangard Labs | fluoxetine hydrochloride | 0615-1357 |
| Rebel Distributors Corp | fluoxetine | 21695-054 |
| Contract Pharmacy Services-PA | fluoxetine | 67046-210 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing COLLOIDAL SILICON DIOXIDE
Excipient focus: CROSCARMELLOSE SODIUM
fluoxetine drug variants containing CROSCARMELLOSE SODIUM
fluoxetine drug variants not containing CROSCARMELLOSE SODIUM
Excipient focus: CROSPOVIDONE
fluoxetine drug variants containing CROSPOVIDONE
fluoxetine drug variants not containing CROSPOVIDONE
Excipient focus: D&C RED NO. 28
fluoxetine drug variants containing D&C RED NO. 28
| Company | Ingredient | NDC |
|---|---|---|
| Teva Pharmaceuticals USA Inc | fluoxetine | 0093-7198 |
| AvKARE | fluoxetine | 42291-398 |
| Proficient Rx LP | fluoxetine | 71205-188 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing D&C RED NO. 28
Excipient focus: D&C YELLOW NO. 10
fluoxetine drug variants containing D&C YELLOW NO. 10
fluoxetine drug variants not containing D&C YELLOW NO. 10
Excipient focus: D&C YELLOW NO. 10 ALUMINUM LAKE
fluoxetine drug variants containing D&C YELLOW NO. 10 ALUMINUM LAKE
fluoxetine drug variants not containing D&C YELLOW NO. 10 ALUMINUM LAKE
Excipient focus: DIMETHICONE
fluoxetine drug variants containing DIMETHICONE
| Company | Ingredient | NDC |
|---|---|---|
| Teva Pharmaceuticals USA Inc | fluoxetine | 0093-7198 |
| Dista Products Company | fluoxetine hydrochloride | 0777-3104 |
| AvKARE | fluoxetine | 42291-398 |
| Proficient Rx LP | fluoxetine | 71205-188 |
| Prodigy Health Supplier | fluoxetine hydrochloride | 76365-0101 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing DIMETHICONE
Excipient focus: FD&C BLUE NO. 1
fluoxetine drug variants containing FD&C BLUE NO. 1
fluoxetine drug variants not containing FD&C BLUE NO. 1
Excipient focus: FD&C BLUE NO. 1 ALUMINUM LAKE
fluoxetine drug variants containing FD&C BLUE NO. 1 ALUMINUM LAKE
fluoxetine drug variants not containing FD&C BLUE NO. 1 ALUMINUM LAKE
Excipient focus: FD&C BLUE NO. 2
fluoxetine drug variants containing FD&C BLUE NO. 2
fluoxetine drug variants not containing FD&C BLUE NO. 2
Excipient focus: FD&C BLUE NO. 2--ALUMINUM LAKE
fluoxetine drug variants containing FD&C BLUE NO. 2--ALUMINUM LAKE
| Company | Ingredient | NDC |
|---|---|---|
| Teva Pharmaceuticals USA Inc | fluoxetine | 0093-7188 |
| Teva Pharmaceuticals USA Inc | fluoxetine | 0093-7198 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing FD&C BLUE NO. 2--ALUMINUM LAKE
Excipient focus: FD&C GREEN NO. 3
fluoxetine drug variants containing FD&C GREEN NO. 3
| Company | Ingredient | NDC |
|---|---|---|
| Physicians Total Care Inc | fluoxetine hydrochloride | 54868-5663 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing FD&C GREEN NO. 3
Excipient focus: FD&C RED NO. 3
fluoxetine drug variants containing FD&C RED NO. 3
fluoxetine drug variants not containing FD&C RED NO. 3
Excipient focus: FD&C RED NO. 40
fluoxetine drug variants containing FD&C RED NO. 40
fluoxetine drug variants not containing FD&C RED NO. 40
Excipient focus: FD&C YELLOW NO. 6
fluoxetine drug variants containing FD&C YELLOW NO. 6
fluoxetine drug variants not containing FD&C YELLOW NO. 6
Excipient focus: FERRIC OXIDE BLACK
fluoxetine drug variants containing FERRIC OXIDE BLACK
| Company | Ingredient | NDC |
|---|---|---|
| NCS HealthCare of KY Inc dba Vangard Labs | fluoxetine hydrochloride | 0615-1357 |
| Rebel Distributors Corp | fluoxetine | 21695-054 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing FERRIC OXIDE BLACK
Excipient focus: FERRIC OXIDE RED
fluoxetine drug variants containing FERRIC OXIDE RED
| Company | Ingredient | NDC |
|---|---|---|
| NCS HealthCare of KY Inc dba Vangard Labs | fluoxetine hydrochloride | 0615-1387 |
| DrReddy's Laboratories Limited | fluoxetine hydrochloride | 55111-284 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing FERRIC OXIDE RED
Excipient focus: FERRIC OXIDE YELLOW
fluoxetine drug variants containing FERRIC OXIDE YELLOW
fluoxetine drug variants not containing FERRIC OXIDE YELLOW
Excipient focus: FERROSOFERRIC OXIDE
fluoxetine drug variants containing FERROSOFERRIC OXIDE
fluoxetine drug variants not containing FERROSOFERRIC OXIDE
Excipient focus: GELATIN
fluoxetine drug variants containing GELATIN
fluoxetine drug variants not containing GELATIN
Excipient focus: GLYCERIN
fluoxetine drug variants containing GLYCERIN
fluoxetine drug variants not containing GLYCERIN
Excipient focus: GLYCINE
fluoxetine drug variants containing GLYCINE
| Company | Ingredient | NDC |
|---|---|---|
| DrReddy's Laboratories Limited | fluoxetine hydrochloride | 55111-284 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing GLYCINE
Excipient focus: HYDROCHLORIC ACID
fluoxetine drug variants containing HYDROCHLORIC ACID
| Company | Ingredient | NDC |
|---|---|---|
| PAI Holdings LLC dba PAI Pharma | fluoxetine hydrochloride | 0121-0721 |
| REMEDYREPACK INC | fluoxetine hydrochloride | 70518-3838 |
| ANI Pharmaceuticals Inc | fluoxetine hydrochloride | 70954-600 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing HYDROCHLORIC ACID
Excipient focus: HYPROMELLOSE
fluoxetine drug variants containing HYPROMELLOSE
fluoxetine drug variants not containing HYPROMELLOSE
Excipient focus: HYPROMELLOSE 2910
fluoxetine drug variants containing HYPROMELLOSE 2910
fluoxetine drug variants not containing HYPROMELLOSE 2910
Excipient focus: HYPROMELLOSE PHTHALATE
fluoxetine drug variants containing HYPROMELLOSE PHTHALATE
| Company | Ingredient | NDC |
|---|---|---|
| DrReddy's Laboratories Limited | fluoxetine hydrochloride | 55111-284 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing HYPROMELLOSE PHTHALATE
Excipient focus: HYPROMELLOSES
fluoxetine drug variants containing HYPROMELLOSES
fluoxetine drug variants not containing HYPROMELLOSES
Excipient focus: INDIGOTINDISULFONATE SODIUM
fluoxetine drug variants containing INDIGOTINDISULFONATE SODIUM
| Company | Ingredient | NDC |
|---|---|---|
| AvKARE | fluoxetine | 42291-398 |
| Proficient Rx LP | fluoxetine hydrochloride | 63187-218 |
| Proficient Rx LP | fluoxetine | 71205-188 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing INDIGOTINDISULFONATE SODIUM
Excipient focus: ISOPROPYL ALCOHOL
fluoxetine drug variants containing ISOPROPYL ALCOHOL
fluoxetine drug variants not containing ISOPROPYL ALCOHOL
Excipient focus: LACTOSE MONOHYDRATE
fluoxetine drug variants containing LACTOSE MONOHYDRATE
fluoxetine drug variants not containing LACTOSE MONOHYDRATE
Excipient focus: LECITHIN, SOYBEAN
fluoxetine drug variants containing LECITHIN, SOYBEAN
| Company | Ingredient | NDC |
|---|---|---|
| Contract Pharmacy Services-PA | fluoxetine | 67046-210 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing LECITHIN, SOYBEAN
Excipient focus: LUPROSTIOL
fluoxetine drug variants containing LUPROSTIOL
| Company | Ingredient | NDC |
|---|---|---|
| Dr Reddy's Laboratories Inc | fluoxetine hydrochloride | 43598-632 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing LUPROSTIOL
Excipient focus: MAGNESIUM STEARATE
fluoxetine drug variants containing MAGNESIUM STEARATE
fluoxetine drug variants not containing MAGNESIUM STEARATE
| Company | Ingredient | NDC |
|---|---|---|
| Teva Pharmaceuticals USA Inc | fluoxetine | 0093-7198 |
| Major Pharmaceuticals | fluoxetine | 0904-7195 |
| NorthStar RxLLC | fluoxetine | 16714-351 |
| Nostrum Laboratories Inc | fluoxetine | 29033-503 |
| Camber Pharmaceuticals Inc | fluoxetine | 31722-903 |
| AvKARE | fluoxetine | 42291-398 |
| Micro Labs Limited | fluoxetine | 42571-387 |
| >Company | >Ingredient | >NDC |
Excipient focus: MANNITOL
fluoxetine drug variants containing MANNITOL
fluoxetine drug variants not containing MANNITOL
Excipient focus: METHYLENE CHLORIDE
fluoxetine drug variants containing METHYLENE CHLORIDE
| Company | Ingredient | NDC |
|---|---|---|
| DrReddy's Laboratories Limited | fluoxetine hydrochloride | 55111-284 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing METHYLENE CHLORIDE
Excipient focus: METHYLPARABEN
fluoxetine drug variants containing METHYLPARABEN
| Company | Ingredient | NDC |
|---|---|---|
| Dista Products Company | fluoxetine hydrochloride | 0777-3104 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing METHYLPARABEN
Excipient focus: MICROCRYSTALLINE CELLULOSE 102
fluoxetine drug variants containing MICROCRYSTALLINE CELLULOSE 102
fluoxetine drug variants not containing MICROCRYSTALLINE CELLULOSE 102
Excipient focus: PATENT BLUE V
fluoxetine drug variants containing PATENT BLUE V
| Company | Ingredient | NDC |
|---|---|---|
| Micro Labs Limited | fluoxetine | 42571-387 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing PATENT BLUE V
Excipient focus: PEPPERMINT
fluoxetine drug variants containing PEPPERMINT
| Company | Ingredient | NDC |
|---|---|---|
| Saptalis Pharmaceuticals LLC | fluoxetine | 71656-089 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing PEPPERMINT
Excipient focus: POLYDEXTROSE
fluoxetine drug variants containing POLYDEXTROSE
| Company | Ingredient | NDC |
|---|---|---|
| PEL HEALTHCARE LLC | fluoxetine | 80426-044 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing POLYDEXTROSE
Excipient focus: POLYETHYLENE GLYCOL
fluoxetine drug variants containing POLYETHYLENE GLYCOL
fluoxetine drug variants not containing POLYETHYLENE GLYCOL
Excipient focus: POLYETHYLENE GLYCOL 3350
fluoxetine drug variants containing POLYETHYLENE GLYCOL 3350
fluoxetine drug variants not containing POLYETHYLENE GLYCOL 3350
Excipient focus: POLYETHYLENE GLYCOL 400
fluoxetine drug variants containing POLYETHYLENE GLYCOL 400
| Company | Ingredient | NDC |
|---|---|---|
| Aurobindo Pharma Limited | fluoxetine | 59651-308 |
| Strides Pharma Science Limited | fluoxetine | 64380-902 |
| MedVantx Inc | fluoxetine | 66116-467 |
| REMEDYREPACK INC | fluoxetine | 70518-4428 |
| REMEDYREPACK INC | fluoxetine | 70518-4429 |
| Bryant Ranch Prepack | fluoxetine | 71335-2778 |
| Bryant Ranch Prepack | fluoxetine | 71335-2784 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing POLYETHYLENE GLYCOL 400
Excipient focus: POLYETHYLENE GLYCOL 6000
fluoxetine drug variants containing POLYETHYLENE GLYCOL 6000
| Company | Ingredient | NDC |
|---|---|---|
| Teva Pharmaceuticals USA Inc | fluoxetine | 0093-7188 |
| Proficient Rx LP | fluoxetine hydrochloride | 63187-218 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing POLYETHYLENE GLYCOL 6000
Excipient focus: POLYETHYLENE GLYCOL 8000
fluoxetine drug variants containing POLYETHYLENE GLYCOL 8000
| Company | Ingredient | NDC |
|---|---|---|
| Teva Pharmaceuticals USA Inc | fluoxetine | 0093-7188 |
| Proficient Rx LP | fluoxetine hydrochloride | 63187-218 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing POLYETHYLENE GLYCOL 8000
Excipient focus: POLYETHYLENE GLYCOLS
fluoxetine drug variants containing POLYETHYLENE GLYCOLS
| Company | Ingredient | NDC |
|---|---|---|
| NCS HealthCare of KY Inc dba Vangard Labs | fluoxetine | 0615-5501 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing POLYETHYLENE GLYCOLS
Excipient focus: POLYSORBATE 80
fluoxetine drug variants containing POLYSORBATE 80
fluoxetine drug variants not containing POLYSORBATE 80
Excipient focus: POLYVINYL ALCOHOL
fluoxetine drug variants containing POLYVINYL ALCOHOL
fluoxetine drug variants not containing POLYVINYL ALCOHOL
Excipient focus: POTASSIUM HYDROXIDE
fluoxetine drug variants containing POTASSIUM HYDROXIDE
| Company | Ingredient | NDC |
|---|---|---|
| Accord Healthcare Inc | fluoxetine | 16729-208 |
| Camber Pharmaceuticals Inc | fluoxetine | 31722-903 |
| Micro Labs Limited | fluoxetine | 42571-387 |
| Aurobindo Pharma Limited | fluoxetine | 59651-898 |
| Direct_Rx | fluoxetine | 61919-745 |
| DIRECT RX | fluoxetine | 61919-869 |
| Direct_Rx | fluoxetine | 61919-885 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing POTASSIUM HYDROXIDE
Excipient focus: POVIDONE
fluoxetine drug variants containing POVIDONE
fluoxetine drug variants not containing POVIDONE
Excipient focus: POVIDONE K30
fluoxetine drug variants containing POVIDONE K30
fluoxetine drug variants not containing POVIDONE K30
Excipient focus: PROPYLENE GLYCOL
fluoxetine drug variants containing PROPYLENE GLYCOL
fluoxetine drug variants not containing PROPYLENE GLYCOL
Excipient focus: PROPYLPARABEN
fluoxetine drug variants containing PROPYLPARABEN
| Company | Ingredient | NDC |
|---|---|---|
| Dista Products Company | fluoxetine hydrochloride | 0777-3104 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing PROPYLPARABEN
Excipient focus: RAW SUGAR
fluoxetine drug variants containing RAW SUGAR
| Company | Ingredient | NDC |
|---|---|---|
| DrReddy's Laboratories Limited | fluoxetine hydrochloride | 55111-284 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing RAW SUGAR
Excipient focus: SHELLAC
fluoxetine drug variants containing SHELLAC
fluoxetine drug variants not containing SHELLAC
Excipient focus: SILICON DIOXIDE
fluoxetine drug variants containing SILICON DIOXIDE
fluoxetine drug variants not containing SILICON DIOXIDE
Excipient focus: SODIUM BENZOATE
fluoxetine drug variants containing SODIUM BENZOATE
| Company | Ingredient | NDC |
|---|---|---|
| PAI Holdings LLC dba PAI Pharma | fluoxetine hydrochloride | 0121-0721 |
| REMEDYREPACK INC | fluoxetine hydrochloride | 70518-3838 |
| ANI Pharmaceuticals Inc | fluoxetine hydrochloride | 70954-600 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing SODIUM BENZOATE
Excipient focus: SODIUM HYDROXIDE
fluoxetine drug variants containing SODIUM HYDROXIDE
fluoxetine drug variants not containing SODIUM HYDROXIDE
Excipient focus: SODIUM LAURYL SULFATE
fluoxetine drug variants containing SODIUM LAURYL SULFATE
| Company | Ingredient | NDC |
|---|---|---|
| Camber Pharmaceuticals Inc | fluoxetine | 31722-903 |
| Micro Labs Limited | fluoxetine | 42571-387 |
| Medsource Pharmaceuticals | fluoxetine | 45865-451 |
| Aurobindo Pharma Limited | fluoxetine | 59651-898 |
| Direct_Rx | fluoxetine | 61919-745 |
| DIRECT RX | fluoxetine | 61919-869 |
| Direct_Rx | fluoxetine | 61919-885 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing SODIUM LAURYL SULFATE
Excipient focus: SODIUM PROPIONATE
fluoxetine drug variants containing SODIUM PROPIONATE
| Company | Ingredient | NDC |
|---|---|---|
| Dista Products Company | fluoxetine hydrochloride | 0777-3104 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing SODIUM PROPIONATE
Excipient focus: STARCH, CORN
fluoxetine drug variants containing STARCH, CORN
fluoxetine drug variants not containing STARCH, CORN
Excipient focus: STARCH, PREGELATINIZED CORN
fluoxetine drug variants containing STARCH, PREGELATINIZED CORN
fluoxetine drug variants not containing STARCH, PREGELATINIZED CORN
Excipient focus: SUCROSE
fluoxetine drug variants containing SUCROSE
fluoxetine drug variants not containing SUCROSE
Excipient focus: TALC
fluoxetine drug variants containing TALC
fluoxetine drug variants not containing TALC
Excipient focus: THIAMINE
fluoxetine drug variants containing THIAMINE
| Company | Ingredient | NDC |
|---|---|---|
| Prodigy Health Supplier | fluoxetine hydrochloride | 76365-0101 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing THIAMINE
Excipient focus: TITANIUM DIOXIDE
fluoxetine drug variants containing TITANIUM DIOXIDE
fluoxetine drug variants not containing TITANIUM DIOXIDE
Excipient focus: TRIACETIN
fluoxetine drug variants containing TRIACETIN
| Company | Ingredient | NDC |
|---|---|---|
| PEL HEALTHCARE LLC | fluoxetine | 80426-044 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing TRIACETIN
Excipient focus: TRIETHYL CITRATE
fluoxetine drug variants containing TRIETHYL CITRATE
| Company | Ingredient | NDC |
|---|---|---|
| DrReddy's Laboratories Limited | fluoxetine hydrochloride | 55111-284 |
| >Company | >Ingredient | >NDC |
fluoxetine drug variants not containing TRIETHYL CITRATE
Excipient focus: WATER
fluoxetine drug variants containing WATER
fluoxetine drug variants not containing WATER
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