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Last Updated: March 18, 2025

Investigational Drug Information for Tegafur


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What is the development status for investigational drug Tegafur?

Tegafur is an investigational drug.

There have been 158 clinical trials for Tegafur. The most recent clinical trial was a Phase 3 trial, which was initiated on September 1st 2014.

The most common disease conditions in clinical trials are Stomach Neoplasms, Adenocarcinoma, and Carcinoma. The leading clinical trial sponsors are Fudan University, National Taiwan University Hospital, and Taiho Pharmaceutical Co., Ltd.

Recent Clinical Trials for Tegafur
TitleSponsorPhase
Consolidation of Toripalimab After Chemoradiotherapy in Elderly Esophageal Cancer (EC-CRT-007)Fifth Affiliated Hospital, Sun Yat-Sen UniversityPhase 2
Consolidation of Toripalimab After Chemoradiotherapy in Elderly Esophageal Cancer (EC-CRT-007)Nanfang Hospital, Southern Medical UniversityPhase 2
Consolidation of Toripalimab After Chemoradiotherapy in Elderly Esophageal Cancer (EC-CRT-007)Wuhan UniversityPhase 2

See all Tegafur clinical trials

Clinical Trial Summary for Tegafur

Top disease conditions for Tegafur
Top clinical trial sponsors for Tegafur

See all Tegafur clinical trials

Tegafur: Development Update and Market Projections

Introduction

Tegafur, also known as 1-(2-Tetrahydrofuryl)-5-fluorouracil, is a small molecule drug that has been in use for several decades, particularly in the treatment of various cancers. Here, we will delve into the current development status and market projections for Tegafur.

Historical Context and Mechanism

Tegafur was first approved in China on January 1, 1983, and it functions as a thymidylate synthase (TYMS) inhibitor. This mechanism involves the inhibition of thymidylate synthase, an enzyme crucial for DNA synthesis, thereby preventing cancer cells from proliferating[4].

Current Development Status

As of the latest available data, Tegafur has already reached the approved phase in several countries, including China. There are no ongoing clinical trials mentioned in recent sources, indicating that the drug is well-established in its therapeutic areas.

Therapeutic Areas

Tegafur is primarily used in the treatment of various cancers, including gastrointestinal cancers and other solid tumors. Its efficacy in these areas has been well-documented, and it remains a significant option in oncology treatment protocols[4].

Market Size and Projections

The global market for Tegafur is anticipated to grow significantly over the coming years. Here are some key market projections:

Global Market Size

As of 2023, the global market size for Tegafur was valued at approximately USD 900 million. This market is expected to expand, reaching around USD 1.5 billion by 2032. This growth is driven by increasing demand for effective cancer treatments and the established efficacy of Tegafur[2].

Regional Market

In specific regions, the market for Tegafur and similar cancer treatments is also seeing significant growth. For instance, the market for cancer treatments in China, where Tegafur has been widely used, continues to grow at a rapid pace due to an increasing patient population and improved healthcare access.

Market Drivers

Several factors are driving the growth of the Tegafur market:

Increasing Cancer Incidence

The global incidence of cancer is rising, which increases the demand for effective treatments like Tegafur. This trend is expected to continue, driving market growth.

Improved Healthcare Access

Enhanced healthcare infrastructure and access to treatments in developing countries are contributing to the increased adoption of Tegafur and other cancer therapies.

Efficacy and Safety Profile

Tegafur's well-documented efficacy and safety profile make it a preferred choice among oncologists, further boosting its market demand.

Market Challenges

Despite the positive market projections, there are some challenges that the Tegafur market may face:

Competition from New Therapies

The oncology market is highly competitive, with new and innovative therapies emerging regularly. These new treatments could potentially compete with Tegafur for market share.

Regulatory Changes

Changes in regulatory environments or approval processes could impact the availability and pricing of Tegafur, affecting its market dynamics.

Conclusion

Tegafur remains a significant player in the oncology market, with a strong historical context and established mechanism of action. The market projections indicate a continued growth trajectory, driven by increasing cancer incidence, improved healthcare access, and the drug's proven efficacy.

Key Takeaways

  • Established Mechanism: Tegafur functions as a TYMS inhibitor, effective in treating various cancers.
  • Global Market Growth: Expected to grow from USD 900 million in 2023 to USD 1.5 billion by 2032.
  • Regional Growth: Significant growth anticipated in regions like China due to increasing patient populations and healthcare access.
  • Market Drivers: Increasing cancer incidence, improved healthcare access, and the drug's efficacy and safety profile.
  • Market Challenges: Competition from new therapies and potential regulatory changes.

FAQs

What is Tegafur used for?

Tegafur is used primarily in the treatment of various cancers, including gastrointestinal cancers and other solid tumors.

When was Tegafur first approved?

Tegafur was first approved in China on January 1, 1983.

What is the mechanism of action of Tegafur?

Tegafur functions as a thymidylate synthase (TYMS) inhibitor, preventing cancer cells from proliferating by inhibiting DNA synthesis.

What are the market projections for Tegafur?

The global market for Tegafur is expected to grow from approximately USD 900 million in 2023 to around USD 1.5 billion by 2032.

What are the main drivers of the Tegafur market growth?

The main drivers include increasing cancer incidence, improved healthcare access, and the drug's established efficacy and safety profile.

Sources

  1. Dataintelo: Tegafur Market Research Report 2032.
  2. Patsnap Synapse: Tegafur - Drug Targets, Indications, Patents.
  3. GitHub: Market-Report/12/Tegafur-Futraful-Market.md.

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