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Last Updated: November 13, 2019

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Drugs in Development Information for Refametinib

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What is the drug development status for Refametinib?

Refametinib is an investigational drug.

There have been 8 clinical trials for Refametinib. The most recent clinical trial was a Phase 2 trial, which was initiated on September 1st 2013.

The most common disease conditions in clinical trials are Carcinoma, Hepatocellular, Carcinoma, and Adenocarcinoma. The leading clinical trial sponsors are Bayer, Samsung Medical Center, and [disabled in preview].

There are twenty-one US patents protecting this investigational drug and two hundred and sixty-five international patents.

Recent Clinical Trials for Refametinib
TitleSponsorPhase
Phase II Study of Refametinib, a MEK Inhibitor, as Second-line Treatment in Advanced Biliary Tract AdenocarcinomaSamsung Medical CenterPhase 2
Refametinib (BAY86-9766) in Combination With Regorafenib (Stivarga, BAY73-4506) in Patients With Advanced or Metastatic CancerBayerPhase 1
Refametinib(BAY86-9766) in RAS Mutant Hepatocellular Carcinoma (HCC)BayerPhase 2

See all Refametinib clinical trials

Clinical Trial Summary for Refametinib

Top disease conditions for Refametinib
Top clinical trial sponsors for Refametinib

See all Refametinib clinical trials

US Patents for Refametinib

Drugname Patent Number Patent Title Patent Assignee Estimated Expiration
Refametinib   Start Trial Derivatives of N-(arylamino) sulfonamides as inhibitors of MEK Ardea Biosciences (San Diego, CA)   Start Trial
Refametinib   Start Trial Polymorphic form of N-(S)-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,- 3-dihydroxypropyl)cyclopropane-1-sulfonamide and uses thereof Ardea Biosciences Inc. (San Diego, CA)   Start Trial
Refametinib   Start Trial Derivatives of N-(arylamino) sulfonamides as inhibitors of MEK Ardea Biosciences (Costa Mesa, CA)   Start Trial
Refametinib   Start Trial Compounds and compositions as protein kinase inhibitors Novartis AG (Basel, CH)   Start Trial
Refametinib   Start Trial Polymorphic form of N-(S)-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,- 3-dihydroxypropyl)cyclopropane-1-sulfonamide and uses thereof Ardea Biosciences, Inc. (San Diego, CA)   Start Trial
>Drugname >Patent Number >Patent Title >Patent Assignee >Estimated Expiration

International Patents for Refametinib

Drugname Country Document Number Estimated Expiration Related US Patent
Refametinib African Regional IP Organization (ARIPO) 2817 2025-07-21   Start Trial
Refametinib Austria 483463 2025-07-21   Start Trial
Refametinib Australia 2006272837 2025-07-21   Start Trial
Refametinib Australia 2007237901 2025-07-21   Start Trial
Refametinib Australia 2008206045 2025-07-21   Start Trial
>Drugname >Country >Document Number >Estimated Expiration >Related US Patent

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Moodys

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