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Drugs in Development Information for LUM001
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What is the drug development status for LUM001?
LUM001 is an investigational drug.
There have been 12 clinical trials for LUM001.
The most recent clinical trial was a Phase 2 trial, which was initiated on May 1st 2019.
The most common disease conditions in clinical trials are Cholestasis, Syndrome, and Liver Diseases. The leading clinical trial sponsors are Shire, Lumena Pharmaceuticals, Inc., and Childhood Liver Disease Research and Education Network.
There are eight US patents protecting this investigational drug and one hundred and twenty-four international patents.
Summary for LUM001
| US Patents | 8 |
| International Patents | 124 |
| US Patent Applications | 6 |
| WIPO Patent Applications | 0 |
| Japanese Patent Applications | 0 |
| Clinical Trial Progress | Phase 2 (2019-05-01) |
| Vendors | 2 |
Recent Clinical Trials for LUM001
| Title | Sponsor | Phase |
|---|---|---|
| MRX-800: A Long-Term Safety Study of Maralixibat in the Treatment of Cholestatic Liver Disease in Subjects Who Previously Participated in a Maralixibat Study | Mirum Pharmaceuticals, Inc. | Phase 2 |
| A Study to Evaluate the Efficacy and Safety of Maralixibat in Subjects With Progressive Familial Intrahepatic Cholestasis (MARCH-PFIC) | Mirum Pharmaceuticals, Inc. | Phase 3 |
| Study to Assess the Relative Potency of Multiple Oral Doses of LUM001 and SHP626 in Overweight and Obese Adults as Assessed by Fecal Bile Acid Excretion | Shire | Phase 1 |
Clinical Trial Summary for LUM001
Top disease conditions for LUM001
Top clinical trial sponsors for LUM001
US Patents for LUM001
| Drugname | Patent Number | Patent Title | Patent Assignee | Estimated Expiration |
|---|---|---|---|---|
| LUM001 | Start Trial | Benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake | G.D. Searle and Company (Skokie, IL) | Start Trial |
| LUM001 | Start Trial | Substituted 5-aryl-benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake | G.D. Searle and Company (Skokie, IL) | Start Trial |
| LUM001 | Start Trial | Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake | G.D. Searle and Company (Skokie, IL) | Start Trial |
| LUM001 | Start Trial | Method of preparing enantiomerically-enriched tetrahydrobenzothiepine oxides | Start Trial | |
| LUM001 | Start Trial | Benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake | G.D. Searle & Co. (Skokie, IL) | Start Trial |
| LUM001 | Start Trial | Mono- and di-fluorinated benzothiepine compounds as inhibitors of apical sodium co-dependent bile acid transport (ASBT) and taurocholate uptake | G.D. Searle, LLC (St. Louis, MO) | Start Trial |
| >Drugname | >Patent Number | >Patent Title | >Patent Assignee | >Estimated Expiration |
International Patents for LUM001
| Drugname | Country | Document Number | Estimated Expiration | Related US Patent |
|---|---|---|---|---|
| LUM001 | Argentina | 019880 | 2018-07-02 | Start Trial |
| LUM001 | Austria | 199718 | 2014-09-13 | Start Trial |
| LUM001 | Austria | 234829 | 2014-09-13 | Start Trial |
| LUM001 | Austria | 256122 | 2014-09-13 | Start Trial |
| LUM001 | Austria | 303378 | 2014-09-13 | Start Trial |
| LUM001 | Australia | 1721399 | 2014-09-13 | Start Trial |
| >Drugname | >Country | >Document Number | >Estimated Expiration | >Related US Patent |
