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Drugs in Development Information for INC280
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What is the drug development status for INC280?
INC280 is an investigational drug.
There have been 34 clinical trials for INC280.
The most recent clinical trial was a Phase 2 trial, which was initiated on May 31st 2017.
The most common disease conditions in clinical trials are Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, and Carcinoma. The leading clinical trial sponsors are Novartis Pharmaceuticals, Novartis, and National Cancer Institute (NCI).
There are twenty-one US patents protecting this investigational drug and three hundred and forty-six international patents.
Summary for INC280
| US Patents | 21 |
| International Patents | 346 |
| US Patent Applications | 52 |
| WIPO Patent Applications | 304 |
| Japanese Patent Applications | 0 |
| Clinical Trial Progress | Phase 2 (2017-05-31) |
| Vendors | 68 |
Recent Clinical Trials for INC280
| Title | Sponsor | Phase |
|---|---|---|
| Study of Capmatinib in Chinese Adult Patients With Advanced Non-small Cell Lung Cancer Harboring MET Exon 14 Skipping Mutation | Novartis Pharmaceuticals | Phase 2 |
| Study of Capmatinib Efficacy in Comparison With Docetaxel in Previously Treated Participants With Non-small Cell Lung Cancer Harboring MET Exon 14 Skipping Mutation | Novartis Pharmaceuticals | Phase 3 |
| Study of Capmatinib and Spartalizumab/Placebo in Advanced NSCLC Patients With MET Exon 14 Skipping Mutations | Novartis Pharmaceuticals | Phase 2 |
Clinical Trial Summary for INC280
Top disease conditions for INC280
Top clinical trial sponsors for INC280
US Patents for INC280
| Drugname | Patent Number | Patent Title | Patent Assignee | Estimated Expiration |
|---|---|---|---|---|
| INC280 | Start Trial | Methods for treating cancer using TOR kinase inhibitor combination therapy comprising administering substituted pyrazino[2,3-b]pyrazines | Signal Pharmaceuticals, LLC (San Diego, CA) | Start Trial |
| INC280 | Start Trial | Tablet formulation of 2-fluoro-N-methyl-4-[ 7-( quinolin-6-ylmethyl) imidazo [1,2-B] [1,2,4] triazin-2-yl] benzamide | Novartis AG (Basel, CH) | Start Trial |
| INC280 | Start Trial | Combination therapy | NOVARTIS AG (Basel, CH) | Start Trial |
| INC280 | Start Trial | Salts of 2-fluoro-N-methyl-4-[7-(quinolin-6-yl-methyl)-imidazo[1,2-B][1,2,- 4]triazin-2-yl]benzamide and processes related to preparing the same | INCYTE INCORPORATION (Wilmington, DE) INCYTE HOLDINGS CORPORATION (Wilmington, DE) | Start Trial |
| INC280 | Start Trial | Compositions and methods for activating "stimulator of interferon gene"--dependent signalling | ADURO BIOTECH, INC. (Berkeley, CA) | Start Trial |
| >Drugname | >Patent Number | >Patent Title | >Patent Assignee | >Estimated Expiration |
International Patents for INC280
| Drugname | Country | Document Number | Estimated Expiration | Related US Patent |
|---|---|---|---|---|
| INC280 | European Patent Office | EP3131552 | 2034-04-16 | Start Trial |
| INC280 | Japan | JP2017514806 | 2034-04-16 | Start Trial |
| INC280 | Japan | JP2019070012 | 2034-04-16 | Start Trial |
| INC280 | New Zealand | NZ629860 | 2034-04-16 | Start Trial |
| INC280 | World Intellectual Property Organization (WIPO) | WO2015160868 | 2034-04-16 | Start Trial |
| >Drugname | >Country | >Document Number | >Estimated Expiration | >Related US Patent |
