Dimethylxanthenone Acetic Acid in Treating Patients With Solid Tumors
Completed
University of Glasgow
Phase 1
RATIONALE: Dimethylxanthenone acetic acid may stop the growth of cancer cells by stopping
blood flow to the tumor.
PURPOSE: Phase I trial to study the effectiveness of dimethylxanthenone acetic acid in
treating patients with solid tumors that have not responded to previous therapy.
Paclitaxel, Carboplatin, and Dimethylxanthenone Acetic Acid in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Completed
Swiss Group for Clinical Cancer Research
Phase 2
RATIONALE: Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different
ways to stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Dimethylxanthenone acetic acid may stop the growth of small cell lung cancer by
blocking blood flow to the tumor. Giving paclitaxel and carboplatin together with
dimethylxanthenone acetic acid may kill more tumor cells.
PURPOSE: This phase II trial is studying the side effects of giving paclitaxel and
carboplatin together with dimethylxanthenone acetic acid and to see how well they work in
treating patients with extensive-stage small cell lung cancer.
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