CLINICAL TRIALS PROFILE FOR PEFICITINIB

Clinical Trials for Peficitinib

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT01096862 ↗	A Study to Explore Efficacy and Safety of ASP015K in Subjects With Moderate to Severe Psoriasis	Completed	Astellas Pharma Inc	Phase 2	The purpose of this study is to explore the efficacy and safety of multiple, escalating doses of ASP015K when compared to placebo in subjects with moderate to severe plaque psoriasis.
NCT01225224 ↗	Single and Multiple Oral Administration Study of ASP015K in Healthy Nonelderly Volunteers	Completed	Astellas Pharma Inc	Phase 1	A study to evaluate the safety, tolerability and PK profiles of single and multiple doses of ASP015K in healthy nonelderly men.
NCT01554696 ↗	A Study to Evaluate the Safety and Efficacy of ASP015K in Moderate to Severe Rheumatoid Arthritis Subjects Who Have Had an Inadequate Response to Methotrexate	Completed	Astellas Pharma Inc	Phase 2	The purpose of this study is to evaluate the safety and efficacy of ASP015K in moderate to severe rheumatoid arthritis subjects who are methotrexate-inadequate responders (MTX-IR).
NCT01565655 ↗	A Study to Evaluate the Safety and Efficacy of ASP015K in Moderate to Severe Rheumatoid Arthritis	Completed	Astellas Pharma Global Development, Inc.	Phase 2	The purpose of this study is to evaluate the safety and efficacy of ASP015K in moderate to severe rheumatoid arthritis (RA) subjects
NCT01638013 ↗	A Study to Continue ASP015K Treatment to Rheumatoid Arthritis Patients Who Completed Phase IIb Study or Phase III Study of ASP015K	Completed	Astellas Pharma Inc	Phase 3	This study evaluated the safety and efficacy of long-term administration of ASP015K in patients who have completed Phase IIb or Phase III studies.

Clinical Trial Conditions for Peficitinib

Condition Name

Condition Name for
Intervention	Trials
Arthritis, Rheumatoid	5
Rheumatoid Arthritis	3
Healthy Volunteers	2
Healthy Volunteer	1

Condition MeSH

Condition MeSH for
Intervention	Trials
Arthritis	9
Arthritis, Rheumatoid	9
Psoriasis	1

Clinical Trial Locations for Peficitinib

Trials by Country

Trials by Country for
Location	Trials
Japan	97
United States	52
Mexico	5
Poland	4
Hungary	3

Trials by US State

Trials by US State for
Location	Trials
Alabama	5
Tennessee	4
Kentucky	4
Florida	4
California	4

Clinical Trial Progress for Peficitinib

Clinical Trial Phase

Clinical Trial Phase for
Clinical Trial Phase	Trials
Phase 3	4
Phase 2	5
Phase 1	5

Clinical Trial Status

Clinical Trial Status for
Clinical Trial Phase	Trials
Completed	13
Active, not recruiting	1

Clinical Trial Sponsors for Peficitinib

Sponsor Name

Sponsor Name for
Sponsor	Trials
Astellas Pharma Inc	10
Astellas Pharma Global Development, Inc.	2
Astellas Pharma China, Inc.	2

Sponsor Type

Sponsor Type for
Sponsor	Trials
Industry	15