You're using a free limited version of DrugPatentWatch: Upgrade for Complete Access

Last Updated: June 21, 2025

Drug Sales Trends for ESTRING


✉ Email this page to a colleague

« Back to Dashboard


Payment Methods and Pharmacy Types for ESTRING (2021)

Revenues by Pharmacy Type

Pharmacy Type Revenues
MAIL-ORDER $14,133,077
INSIDE ANOTHER STORE $47,883,451
[disabled in preview] $65,738,224
This preview shows a limited data set
Subscribe for full access, or try a Trial

Units Sold by Pharmacy Type

Pharmacy Type Units
MAIL-ORDER 29,628
INSIDE ANOTHER STORE 100,698
[disabled in preview] 138,431
This preview shows a limited data set
Subscribe for full access, or try a Trial

Revenues by Payment Method

Payment Method Revenues
MEDICARE $40,847,513
PRIVATE INSURANCE $57,111,399
[disabled in preview] $29,795,840
This preview shows a limited data set
Subscribe for full access, or try a Trial
Drug Sales Revenue Trends for ESTRING
Drug Units Sold Trends for ESTRING

Annual Sales Revenues and Units Sold for ESTRING

These sales figures are drawn from a US national survey of drug expenditures
Drug Name Revenues (USD) Units Year
ESTRING ⤷  Try for Free ⤷  Try for Free 2021
ESTRING ⤷  Try for Free ⤷  Try for Free 2020
ESTRING ⤷  Try for Free ⤷  Try for Free 2019
ESTRING ⤷  Try for Free ⤷  Try for Free 2018
ESTRING ⤷  Try for Free ⤷  Try for Free 2017
>Drug Name >Revenues (USD) >Units >Year

Market Analysis and Sales Projections for Estring

Introduction to Estring

Estring is a vaginal ring marketed by Pfizer, designed to treat vaginal atrophy related to menopause. It continuously releases a low dose of estradiol, a female sex hormone, to alleviate symptoms such as painful intercourse and vaginal dryness.

Market Size and Growth

The market for estrogen replacement therapies, which includes Estring, is significant and growing. The global estrogen replacement therapy market is estimated to reach $13.2 billion by 2027, growing at a CAGR of 5.7% during the forecast period 2022-2027[2].

Price Trends and Affordability

Over the years, the prices of Estring and other estradiol products have increased substantially. For instance, the price of Estring rose from less than $300 at the start of 2014 to more than $500 by 2018. Similarly, Allergan's Estrace Cream saw its price increase from about $200 to $330 per tube over the same period[1].

Despite these price hikes, Estring remains covered by most insurance plans for the majority of patients. However, patients often face higher out-of-pocket costs due to increased deductibles and copays. To mitigate these costs, some patients opt for purchasing estradiol products from overseas outlets, where they can be significantly cheaper[1].

Generic Competition

The introduction of generic versions of estradiol products has provided some relief in terms of pricing. For example, Amneal launched a generic to Novo Nordisk's Vagifem in 2016, and Teva launched another generic in 2017. Additionally, after Estrace Cream lost its patent protections in December 2017, generics from companies like Mylan and Teva entered the market, potentially driving prices down[1].

However, Estring itself does not have a generic version available, which maintains its market position but also keeps its prices higher compared to generic alternatives[1].

Sales Forecast

The sales forecast for Estring and similar products is influenced by several factors, including the growing awareness of menopausal symptoms and the need for hormone replacement therapies. Here are some key points:

  • Historical Sales: The postmenopausal vaginal atrophy market, where Estring is a key player, has experienced anemic growth in the past but is expected to undergo significant changes. The market has a large untreated population due to low diagnosis rates and safety concerns with existing therapies[4].

  • Future Projections: The vaginal rings market, which includes Estring, was valued at $1,932.95 million in 2022 and is projected to reach $2,791.2 million by 2030, growing at a CAGR of 4.7% during the forecast period. While Estring is not the dominant product in this market (Nuvaring holds that position), it remains a significant player[5].

  • Regional Insights: North America, particularly the U.S., accounts for the highest revenue share in the estrogen replacement therapy market. This region is expected to continue dominating the market due to high demand and advanced healthcare infrastructure[2].

Market Dynamics

Several factors drive the demand for Estring and other estrogen replacement therapies:

  • Increasing Awareness: Growing awareness about menopausal symptoms and the benefits of hormone replacement therapies is driving market growth[2].
  • Untreated Population: A significant portion of the population suffering from postmenopausal vaginal atrophy remains untreated, offering a large potential market for Estring and similar products[4].
  • Safety Concerns: Despite the benefits, estrogen-based therapies are associated with elevated risks of breast cancer, endometrial cancer, and stroke, which can hamper market growth[4].

Competitive Landscape

The market for vaginal rings and estrogen replacement therapies is competitive, with several key players:

  • Pfizer Inc.: Markets Estring.
  • Allergan: Markets Estrace Cream.
  • Novo Nordisk: Markets Vagifem, which has generic competitors.
  • Merck & Co., Inc.: Involved in the market through partnerships and generic versions of other vaginal rings[1][5].

Challenges and Opportunities

Challenges

  • Price Sensitivity: High prices of branded products like Estring can deter patients, especially those without comprehensive insurance coverage[1].
  • Safety Concerns: Long-term use of estrogen-based therapies is associated with health risks, which can impact market acceptance[4].

Opportunities

  • Generic Competition: The entry of generic versions can drive prices down and increase market accessibility[1].
  • Growing Awareness: Increasing awareness about menopausal symptoms and the benefits of hormone replacement therapies can expand the market[2].

Key Takeaways

  • Market Growth: The estrogen replacement therapy market, including Estring, is expected to grow significantly, driven by increasing awareness and demand.
  • Price Trends: Despite price hikes, the introduction of generics and patient assistance programs can provide some cost relief.
  • Competitive Landscape: The market is competitive, with several key players and ongoing developments in generic versions.
  • Challenges and Opportunities: Safety concerns and price sensitivity are challenges, while growing awareness and generic competition offer opportunities.

FAQs

1. What is Estring used for? Estring is a vaginal ring used to treat vaginal atrophy related to menopause, alleviating symptoms such as painful intercourse and vaginal dryness.

2. Why have Estring prices increased over the years? Estring prices have increased due to various market and competitive dynamics, including the lack of generic competition and the company's investment in ensuring the quality, safety, and reliability of the product[1].

3. Are there generic versions of Estring available? No, there are currently no generic versions of Estring available, although generics for other estradiol products like Estrace Cream and Vagifem exist[1].

4. How does the competitive landscape affect Estring sales? The competitive landscape, including the presence of other vaginal rings like Nuvaring and Femring, and the introduction of generic versions, influences Estring sales. However, Estring remains a significant player in the market due to its unique features and lack of generic competition[5].

5. What are the future projections for the vaginal rings market? The vaginal rings market, which includes Estring, is projected to grow from $1,932.95 million in 2022 to $2,791.2 million by 2030, at a CAGR of 4.7% during the forecast period[5].

Cited Sources

  1. FiercePharma: "Women's hormone drug prices have climbed for years, but there hasn't been a controversy. Why?"
  2. IndustryArc: "Estrogen Replacement Therapy Market Report, 2022-2027"
  3. Coherent Market Insights: "Estrogen Blockers Market Size, Trends and Forecast to 2030"
  4. BusinessWire: "Research and Markets: Estring (Postmenopausal Vaginal Atrophy) - Forecast and Market Analysis to 2022"
  5. Bizlytik: "Vaginal Rings Market was valued at $1,932.95 million in 2022"
Last updated: 2024-12-31

More… ↓

⤷  Try for Free

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.