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Last Updated: April 17, 2026

Drug Price Trends for NDC 83324-0317


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Best Wholesale Price for NDC 83324-0317

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 83324-0317

Last updated: February 19, 2026

What is the drug associated with NDC 83324-0317?

NDC 83324-0317 is for Nivolumab (Opdivo), a PD-1 inhibitor developed by Bristol-Myers Squibb. It is approved for multiple indications, including melanoma, non-small cell lung cancer, and renal cell carcinoma.

Market Overview

Current Market Landscape

  • Indications: Approved for at least 12 cancer types, including melanoma and lung cancer.
  • Market Size (2023): Estimated global oncology immunotherapy market was valued at approximately $45 billion, predicted to grow annually by 12-15% through 2030.
  • Key Competitors: Pembrolizumab (Keytruda), Atezolizumab (Tecentriq), Durvalumab (Imfinzi).
  • U.S. Market Penetration: Dominated by Keytruda (~$5 billion annual sales), with Opdivo capturing approximately 30-40% market share in the checkpoint inhibitor segment.

Prescription Trends

  • Volume: In 2022, U.S. prescriptions for nivolumab approximated 1.2 million units.
  • Utilization: Growing rapidly due to expanding FDA approvals, combination therapies, and new indications.
  • Pricing Strategy: List price for a 40 mg vial is approximately $1,200; a 240 mg dose costs about $7,200 per administration.

Pricing and Reimbursement Landscape

List Price

Dosage Form Approximate Price Notes
40 mg vial $1,200 Standard initial dose
240 mg dose ~$7,200 Used in combination therapies or higher-dose regimens

Reimbursement

  • Coverage: Primarily via Medicare and private insurers.
  • Cost Management: Manufactures negotiate rebates and formulary placements; patient out-of-pocket costs depend on insurance plan and assistance programs.

Competitive Pricing

Drug Name Indication(s) Price Range (per dose) Market Share
Nivolumab (Opdivo) Multiple cancers $7,200-$8,000 30-40%
Pembrolizumab (Keytruda) Similar indications $7,000-$8,000 ~50%

Price Projection (2023-2030)

Factors Influencing Price Trends

  • Patent Expiration: Expected around 2028, which can lead to biosimilar entry and price competition.
  • Market Expansion: New indications (e.g., breast, colorectal) and combination therapies could sustain high prices temporarily.
  • Regulatory & Policy Changes: Increased price scrutiny may moderate growth or prompt discounts.
  • Manufacturing & Supply Costs: Stable, as biologics manufacturing efficiencies improve.

Projections

Year Estimated Price Range Notes
2023 $7,200 - $8,000 Current rates, with slight variability
2025 $6,800 - $7,800 Slight discounts possible due to price negotiations; biosimilars imminent
2030 $5,500 - $7,000 Entry of biosimilars expected to lower prices by 20-35%

Biosimilar Impact

  • Launch Year(s): Expected between 2026 and 2028.
  • Price Reduction: Biosimilar versions could cut list prices by 20-35%.
  • Market Share Shift: Biosimilars could capture 40-60% of the market by 2030.

Key Considerations for Market and Pricing

  • Patent and Exclusivity: Patent expiry in 2028 is pivotal.
  • Regulatory Approvals: Expanding indications could support sustained pricing.
  • Reimbursement Environment: Increased pressure for value-based pricing.
  • Competitive Dynamics: Strong competition from Keytruda and emerging biosimilars.
  • Manufacturing Costs: Biologic complexity affects margins but remains relatively stable.

Key Takeaways

  • Nivolumab’s market remains robust, driven by broad indications and aggressive competitor positioning.
  • Prices are currently high, but market forces and biosimilar entry will pressure reductions by 2028.
  • Market share gains depend on approval for new indications and combination strategies.
  • The next three years will see minimal price decrease, followed by sharper declines post-patent expiry.

FAQs

  1. What factors could accelerate biosimilar entry?
    Patent expiry, regulatory pathways, and market demand for lower-cost options.

  2. How will new indications affect pricing?
    They can justify higher prices temporarily and expand market share.

  3. What is the impact of pricing on reimbursement strategies?
    Payers demand cost-effectiveness, leading to negotiations, rebates, and value-based agreements.

  4. Is the current list price sustainable?
    Short-term, yes; long-term, biosimilar competition will reduce prices.

  5. What are potential risks for price stability?
    Policy changes, patent litigation, and slower than expected biosimilar adoption.


References

[1] EvaluatePharma. (2023). Pharmaceutical Market Data.
[2] IQVIA. (2023). National Prescription Audit.
[3] FDA. (2022). Biologics Approvals and Indications.
[4] Bristol-Myers Squibb. (2023). Opdivo Product Details.
[5] Centers for Medicare & Medicaid Services. (2023). Reimbursement Data.

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