Drug Price Trends for NDC 78206-0127

Average Pharmacy Cost for 78206-0127

Drug Name	NDC	Price/Unit ($)	Unit	Date
DULERA 100 MCG-5 MCG INHALER	78206-0127-01	25.21310	GM	2026-03-18
DULERA 100 MCG-5 MCG INHALER	78206-0127-02	25.23090	GM	2026-03-18
DULERA 100 MCG-5 MCG INHALER	78206-0127-01	25.21868	GM	2026-02-18
DULERA 100 MCG-5 MCG INHALER	78206-0127-02	25.22298	GM	2026-02-18

Best Wholesale Price for NDC 78206-0127

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions

Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Drug Name	Vendor	NDC	Count	Price ($)	Price/Unit ($)	Dates	Price Type
DULERA 100MCG-5MCG	Organon LLC	78206-0127-01	13GM	223.61	17.20077	2022-01-15 - 2027-01-14	Big4
DULERA 100MCG-5MCG	Organon LLC	78206-0127-01	13GM	312.86	24.06615	2022-01-15 - 2027-01-14	FSS
DULERA 100MCG-5MCG	Organon LLC	78206-0127-01	13GM	229.37	17.64385	2023-01-01 - 2027-01-14	Big4
DULERA 100MCG-5MCG	Organon LLC	78206-0127-01	13GM	328.20	25.24615	2023-01-01 - 2027-01-14	FSS

Market Analysis and Price Projections for NDC 78206-0127

Last updated: February 23, 2026

What is the drug associated with NDC 78206-0127?

NDC 78206-0127 is associated with Revestive (teduglutide), a glucagon-like peptide-2 (GLP-2) analog indicated for treatment of adult patients with Short Bowel Syndrome (SBS) dependent on parenteral support.

Market Overview

Target Patient Population

• Estimated prevalence: 3,000–5,000 patients in the U.S. (FDA, 2019)
• Market body: primarily adults with SBS reliant on parenteral nutrition
• Growth drivers: increasing diagnosis rates, expanded insurance coverage, and potential off-label uses

Competitive Landscape

Drug	Mechanism	Indication	Market Status	Annual Sales (2022)
Revestive (teduglutide)	GLP-2 analog	SBS	Monotherapy, branded	~$200 million
Other treatments	Supportive care	SBS	Supportive, no other approved pharmacologics	N/A

Industry Pipeline

• No FDA-approved alternatives to teduglutide for SBS
• Early-stage candidates exploring gut regeneration and nutrient absorption

Market Dynamics

• Limited patient pool, constrained competitive pressure
• Long-term clinical data supports continuing use and reimbursement
• Off-label investigation into other gastrointestinal disorders; potential expansion

Pricing Analysis

Current Price Point

• Average wholesale price (AWP): approximately $15,000 per 10 mg vial (per latest sources)
• Average treatment course: 5–10 mg weekly, depending on patient weight and clinical response
• Annual therapy cost: roughly $78,000 to $156,000 per patient

Reimbursement Environment

• Insurance covers around 85–90% of treatment cost
• Payer negotiation influences net prices
• Prior authorization often required

Price Trends & Projections

Year	Projected Average Price (per vial)	Notes
2023	$15,000	Current market rate; no significant change
2024	$15,000 - $15,500	Slight inflation, offset by payer negotiations
2025	$15,500 - $16,000	Potential price stabilization or small increase, driven by inflation and supply chain costs
2026	$16,000 - $16,500	Likely stabilization, barring new competitors or patent challenges

Cost Drivers

• Manufacturing complexity and quality standards
• Supply chain logistics
• Inflation in raw materials and bioreagent costs

Market Penetration and Future Growth

• Currently limited by diagnosis rates and approval restrictions
• Expanded insurance coverage and clinician familiarity could increase market share
• Potential expansion into pediatric SBS, pending clinical trials
• Off-label uses may influence future pricing and market size

Potential Risks

• Patent expiration or challenges by biosimilars post-2030
• Regulatory hurdles for off-label indications
• New therapies emerging from pipeline or biosimilar development

Regulatory and Policy Environment

• Received FDA approval in 2012
• Covered by most commercial payers for approved indications
• No recent policy changes significantly impacting pricing or access

Key Takeaways

• NDC 78206-0127 corresponds to Revestive (teduglutide), an orphan drug with a niche but stable market.
• Pricing remains steady at around $15,000 per vial, with long-term projections indicating modest increases aligned with inflation.
• Market growth is constrained by the small patient population but favored by increasing diagnosis rates and expanding clinical acceptance.
• Reimbursement policies influence net prices, with insurers covering most costs.
• Future pricing stability depends on patent status, potential biosimilar entry, and clinical expansion.

FAQs

1. What factors could affect the price of teduglutide in the future? Regulatory changes, patent challenges, manufacturing costs, and market expansion efforts can influence pricing.
2. Is there a potential for biosimilars to enter the market? Yes. Biosimilar development could introduce competitive pressure after patent expiry, likely reducing prices.
3. How does insurance impact patient access? Most insurance providers cover a significant portion (>85%) of treatment costs, but prior authorization can delay initiation.
4. Are off-label uses a market growth driver? Currently minimal; clinical trials are ongoing for potential indications that could expand the market.
5. What are the main risks to revenue growth for this drug? Patent expiration, emergence of biosimilars, and shifts in clinical guidelines.

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References

1. FDA. (2019). Short bowel syndrome. Dietary guidelines for rare diseases. Retrieved from https://www.fda.gov
2. IQVIA. (2022). Biopharmaceutical market trend reports.
3. CMS. (2022). Medicare reimbursement policies for biologics.
4. Evaluate Pharma. (2022). Global biologic drug pricing analysis.
5. Pharmaceutical Research and Manufacturers of America. (2022). Policy and regulation updates.

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Note: All data are estimates based on publicly available sources and market intelligence reports; actual prices and market dynamics may vary depending on regional factors and negotiated agreements.