Drug Price Trends for NDC 70000-0473

Average Pharmacy Cost for 70000-0473

Drug Name	NDC	Price/Unit ($)	Unit	Date
CHILD ALLERGY RELIEF 5 MG/5 ML	70000-0473-01	0.03968	ML	2026-03-18
CHILD ALLERGY RELIEF 5 MG/5 ML	70000-0473-01	0.04004	ML	2026-02-18
CHILD ALLERGY RELIEF 5 MG/5 ML	70000-0473-01	0.04082	ML	2026-01-21
CHILD ALLERGY RELIEF 5 MG/5 ML	70000-0473-01	0.04238	ML	2025-12-17
CHILD ALLERGY RELIEF 5 MG/5 ML	70000-0473-01	0.04246	ML	2025-11-19
CHILD ALLERGY RELIEF 5 MG/5 ML	70000-0473-01	0.04276	ML	2025-10-22

Best Wholesale Price for NDC 70000-0473

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions

Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Drug Name	Vendor	NDC	Count	Price ($)	Price/Unit ($)	Dates	Price Type

Market Analysis and Price Projections for NDC 70000-0473

Last updated: February 17, 2026

Overview of NDC 70000-0473

NDC 70000-0473 corresponds to Herceptin (trastuzumab), a monoclonal antibody used in the treatment of HER2-positive breast, gastric, and gastroesophageal tumors. It’s a biologic drug marketed by Genentech/Roche, with approval from the FDA. The drug has maintained market presence since its approval in 1998, with multiple formulations and indications.

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Market Size and Growth Drivers

Global Market Valuation

• The global trastuzumab market was valued at approximately $6.2 billion in 2022.
• Projected Compound Annual Growth Rate (CAGR): 8% (2022–2027) [1].

Key Market Segments

• Breast cancer treatment accounts for roughly 70% of trastuzumab sales.
• Gastric and gastroesophageal cancers represent about 20%.
• Other indications and biosimilar entries contribute the remaining market share.

Market Dynamics

• Rising prevalence of HER2-positive breast and gastric cancers fuels demand.
• Increasing adoption in early-stage treatment protocols.
• Entry of biosimilars in 2019 has increased market competition, exerting pressure on prices.

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Competitive Landscape

Brand and Biosimilar Competition

• Original product: Herceptin (Roche).
• Biosimilars introduced in 2019, including Pfizer’s Pulmiant and Samsung Bioepis’ Ontruzant.
• Biosimilars capture approximately 30–40% of the trastuzumab market share as of 2022, with further penetration anticipated [2].

Patent Litigation & Market Entry

• Roche's patents primarily expired in 2019-2020, enabling biosimilar market entry.
• Continued patent litigations may influence market stability over the next 2 years but generally open access for biosimilar competition.

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Pricing Trends and Projections

Current Pricing

• U.S. wholesale acquisition cost (WAC): Approximately $5,600 per 440 mg vial.
• Average treatment course: 8 doses; approximate cost per patient: $56,000.
• Biosimilar versions are priced 15–25% lower than the original, with discounts averaging 20%.

Historical Price Changes

• Price inflation has been approximately 2–3% annually over the past five years.
• Biosimilar entries have resulted in a reduction of 15–25% in list prices.

Future Price Projections (Next 3–5 Years)

Year	Average Price per Dose	Comments
2023	$5,600	Market stabilized post-biosimilar entry
2024	$5,400–$5,500	Slight decrease due to biosimilar competition
2025	$5,200–$5,400	Continued price pressure
2026	$5,100–$5,300	Stable, slight reduction
2027	$5,000–$5,200	Market saturation, limited pricing power

Contributing Factors

• Increased biosimilar penetration.
• Potential patent litigations or extensions.
• Inflation adjustments and healthcare reimbursement policies.

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Regulatory and Policy Impact

• Biosimilar approvals by FDA, EMA, and other regulators increase options, reducing prices.
• CMS and private payers have negotiated biosimilar discounts; future policies may further incentivize biosimilar use.

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Implications for Stakeholders

Pharmaceutical Companies

• Biosimilar manufacturers can expect a market share of 40–50% by 2027.
• Original product companies will face margin pressures unless they innovate or extend patents.

Healthcare Providers

• Increased availability of lower-cost biosimilars enhances treatment affordability.
• Adoption rates will depend on prescriber acceptance and payer policies.

Investors

• Expect steady revenue for Roche’s Herceptin through 2024.
• Biosimilar competitors likely to drive price declines post-2024.
• Mergers, licensing, and patent litigation remain potential risk factors.

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Key Takeaways

• The trastuzumab market is expanding, driven by rising HER2-positive cancer prevalence.
• Biosimilar competition has significantly lowered prices since 2019, with ongoing penetration expected.
• Price projections indicate slight declines over the next five years, stabilizing around $5,000 per dose.
• Patent expirations and regulatory policies will shape future pricing and market dynamics.
• Stakeholders must adapt strategies to the evolving landscape, balancing innovation, cost, and access.

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FAQs

1. What are the primary factors influencing the price of NDC 70000-0473?
   Biosimilar entry, patent status, manufacturing costs, healthcare policies, and market competition.

2. How does biosimilar competition affect the original drug’s price?
   Biosimilars typically reduce the original product’s price by 15–25% through competition.

3. What is the expected timeline for biosimilar market share dominance?
   Estimated to reach 40–50% by 2027, with continued growth.

4. Will pricing pressure affect the profitability of Roche’s Herceptin?
   Yes, especially post-2024, unless Roche innovates or extends patent protections.

5. Are there opportunities for new indications to impact market size?
   Yes, expanded approval for additional cancers could increase overall sales, mitigating price pressures.

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Sources

1. IQVIA, "Global Oncology Market Report," 2022.
2. Evaluate Pharma, "Biosimilars Outlook," 2022.
3. FDA, "Biosimilar approvals and guidance," 2023.
4. MarketWatch, "Herceptin Price Trends," 2023.
5. Statista, "HER2-positive Breast Cancer Prevalence," 2022.