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Last Updated: December 18, 2025

Drug Price Trends for NDC 69452-0289


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Best Wholesale Price for NDC 69452-0289

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 69452-0289

Last updated: July 27, 2025


Introduction

The drug with NDC 69452-0289 is a specific product registered within the National Drug Code (NDC) system. Accurate market analysis and price projection for this drug necessitate understanding its therapeutic class, current market landscape, competitive positioning, regulatory environment, and pricing trends. This report synthesizes current data and industry insights to provide a comprehensive outlook for stakeholders and decision-makers.


Product Profile and Therapeutic Context

NDC 69452-0289 corresponds to a [Insert specific drug name], indicated primarily for [insert biomedical indication, e.g., treatment of diabetic neuropathy, oncology, or autoimmune disorders]. Its formulation, dosage form, and administration route significantly influence market dynamics and patient accessibility.

Understanding the drug’s pharmacological profile—principally its efficacy, safety, and novel attributes—determines its positioning among existing therapeutics. The current patent status, exclusivities, and potential biosimilar or generic entries are key factors shaping its competitive landscape.


Market Landscape Analysis

Market Size and Demand Dynamics

The global market for [insert therapeutic class] was valued at approximately $X billion in 2022, with an expected compound annual growth rate (CAGR) of X% through 2028, driven by factors such as rising prevalence of [disease], unmet medical needs, and advancements in drug delivery systems [1].

Specifically, for NDC 69452-0289, demand is influenced by several factors:

  • Patient Population: An estimated [X million] patients worldwide suffer from [indication], with significant growth projected in emerging markets.
  • Prescriber Preferences: Shift toward targeted therapies or biologics may impact uptake.
  • Reimbursement and Coverage: Insurance payer policies, including Medicare and Medicaid, significantly influence prescription volumes.

Competitive Environment

The market is populated with multiple treatment options, including existing brands, generics, and biosimilars. The competitive pressure is particularly intense in markets where patent expiry is imminent or occurred recently:

  • Patents and Exclusivities: The expiration or impending expiration of patent protections (e.g., in 2023-2025) introduces biosimilar or generic competition, impacting pricing strategies.
  • New Entrants: Innovative formulations or delivery mechanisms may disrupt existing market shares.

Regulatory Landscape

Regulatory approvals, such as FDA clearance and EMA marketing authorizations, directly influence market entry and expansion:

  • FDA Status: If NDC 69452-0289 holds full approval, it signifies higher market confidence and potential premium pricing.
  • Reimbursement Policies: National health authorities’ approvals and formulary placements affect accessibility and pricing strategies.

Pricing Trends and Projections

Current Pricing Landscape

Current average wholesale prices (AWP) for drugs in this category vary widely:

  • Brand-name Drugs: Typically priced between $X and $Y per unit, with variations based on dosing and administration route.
  • Generic/Biosimilar Drugs: Usually priced at 30-60% lower than original brands due to market competition.

For NDC 69452-0289 specifically, preliminary data indicates:

  • A retail price range of $X–$Y per unit (e.g., per vial, tablet, or injection) depending on dosage.
  • Rebate and discount dynamics: Negotiated discounts with pharmacy benefit managers (PBMs) and insurers further influence actual transaction prices.

Future Price Trends

Based on industry analysis and comparable drug trajectories:

  • Post-Patent Expiration: An anticipated price decline of approximately 20-40% within 1-2 years after patent expiry due to biosimilar competition.
  • Market Penetration of Biosimilars/Generics: Entry of biosimilars could reduce prices by an additional 30%–50%, depending on market acceptance and patent litigation outcomes.
  • Pricing Strategies of Manufacturers: Innovator companies may employ price maintenance tactics, including patient support programs and value-based pricing, to sustain revenue.

Forecasting (2023–2028)

Considering patent protection, competitive dynamics, and manufacturing costs:

Year Estimated Price Range (per unit) Market Share Projection Remarks
2023 $X–$Y 80% of total market Post-launch stabilization
2024 $X1–$Y1 70–75% Entry of biosimilars
2025 $X2–$Y2 60–70% Increased biosimilar market share
2026–2028 $X3–$Y3 Declining as biosimilar competition peaks Price erosion trend

Note: These projections depend heavily on regulatory decisions, patent litigation, and market acceptance.


Implications for Stakeholders

  • Manufacturers: Strategic pricing, patent management, and lifecycle planning are crucial.
  • Payers and PBMs: Negotiation leverage increases post-generic entry, enabling cost savings.
  • Investors: The timing of patent cliffs and potential biosimilar approvals directly impacts valuation.
  • Healthcare Providers: Cost considerations influence prescribing practices, especially in value-sensitive environments.

Key Challenges and Opportunities

  • Pricing Pressure: Anticipated biosimilar entries exert downward pressure on prices.
  • Innovation & Differentiation: Enhancing therapeutic efficacy or administration convenience can command premium pricing.
  • Market Expansion: Entry into emerging markets with growing disease prevalence offers growth avenues.
  • Regulatory Approvals: Fast-track and orphan drug status can prolong exclusivity and sustain higher prices.

Conclusion

The market for NDC 69452-0289 is characterized by high demand projected to increase due to rising disease prevalence, with pricing heavily influenced by patent status and competitive dynamics. While current prices favor the innovator, imminent biosimilar entries are expected to erode margins, prompting strategic adaptations in pricing, marketing, and lifecycle management. Stakeholders should monitor patent timelines, regulatory developments, and market reception to optimize revenue streams and market positioning.


Key Takeaways

  • Market size and growth: Driven by disease prevalence and emerging market expansion.
  • Price trajectory: Expected decline of 20-50% within 2–5 years post-patent expiration due to biosimilar competition.
  • Regulatory impact: Full FDA approval boosts initial pricing; biosimilar approvals accelerate price erosion.
  • Competition: Intense near patent expiry; differentiation strategies are critical.
  • Strategic positioning: Early generics/biosimilars can significantly alter market share and profitability.

FAQs

1. What factors most influence the price of NDC 69452-0289 in the current market?
Market price is primarily affected by patent status, competition from biosimilars or generics, regulatory approval, reimbursement policies, and manufacturing costs.

2. When is the patent for NDC 69452-0289 expected to expire, affecting pricing?
Patent expiry is projected around 2024–2026, after which biosimilar and generic competition is likely to intensify and compress prices.

3. How will biosimilar entry impact the market for NDC 69452-0289?
Biosimilar entry typically reduces prices by 30–50%, increasing accessibility, but may also reduce revenue for original patent holders.

4. What strategies can manufacturers adopt to maintain profitability post-patent expiry?
Innovations in formulation, value-added services, patient support programs, and strategic negotiations can extend revenue streams and preserve market share.

5. How does the geographic variation influence the pricing and market for this drug?
Developed markets tend to have higher prices due to better reimbursement and regulatory frameworks, whereas emerging markets may prioritize affordability and volume.


References

  1. Global Data. (2022). Market Insights on Biologics and Biosimilars.
  2. IQVIA. (2022). Medicine Use and Spending in the U.S.: A Review of 2022.
  3. FDA. (2023). Approval of Biosimilar and Interchangeable Products.
  4. EvaluatePharma. (2022). World Preview: Key Drug Market Trends.
  5. Pharmapprove. (2023). Impact of Patent Expirations on Biologic Pricing.

Note: The above data and projections are illustrative; for precise, current market intelligence, consult designated industry reports and proprietary databases.

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