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Last Updated: December 30, 2025

Drug Price Trends for NDC 68180-0895


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Market Analysis and Price Projections for NDC 68180-0895

Last updated: July 30, 2025


Introduction

The drug with NDC 68180-0895 is a pharmaceutical product listed within the National Drug Code (NDC) system, which uniquely identifies prescription medications in the United States. While explicit details regarding this specific NDC’s drug name, formulation, and indication are essential, limited public information restricts comprehensive analysis. Nonetheless, a systematic market overview and price projection framework can be established based on available data, industry trends, competitive landscape, and regulatory factors.


Product Overview and Context

Identification and Therapeutic Class:
The NDC code 68180-0895 registers a drug marketed by a specialty pharmaceutical entity. Based on the structure and typical coding conventions, this product likely belongs to a specialized therapeutic segment, potentially monoclonal antibodies, biologics, or targeted therapies, given the manufacturer’s profile.

Regulatory Status:
Prior to analyzing market dynamics, confirmation of regulatory approvals—indications, label extensions, and reimbursement status—is vital. The drug’s FDA approval status influences market penetration and competitive positioning.

Current Market Landscape

Market Size and Demand Drivers:
The therapeutic area associated with NDC 68180-0895 largely dictates market size. For example, if this NDC pertains to a biologic for autoimmune diseases such as rheumatoid arthritis, the U.S. biologics market was valued at approximately $140 billion in 2022, with a CAGR of 8% through 2027 [1].

Patient Population and Adoption Trends:
Target patient populations, prescriber adoption, and reimbursement coverage are primary demand influencers. Emerging therapies or shifting indications can expand or contract the market size. If this drug targets a rare disease (or orphan indication), market potential might be limited but lucrative due to exclusivity rights.

Competitive Landscape:
Key competitors’ offerings, their pricing strategies, and biosimilar activity significantly impact this drug’s market share. The introduction of biosimilars following patent expiry usually exerts downward pressure on prices, impacting revenue projections.

Pricing Dynamics and Cost Factors

List Price and Reimbursement:
Biologics and targeted therapies often command high list prices—averaging $2,000 to $7,000 per dose. Industry reports indicate biologics in the U.S. often have net prices (after discounts and rebates) 20-40% lower than list prices [2].

Impact of Rebates and Negotiations:
Rebate programs and utilization management strategies by insurers influence actual transaction prices, often making net prices significantly lower than initial list prices.

Manufacturing and R&D Costs:
Biotech and biologic drugs face high development costs (~$1 billion) with long development timelines. The cost structure influences pricing strategies, especially in initial launch phases, with subsequent adjustments to sustain profitability.


Market Growth and Price Projection Framework

Factors Influencing Price Trajectories:

  • Patent Status and Biosimilar Entry:
    Pending patent expiration or biosimilar approvals will introduce competitive pressures, likely reducing prices by 20-40% over 3-5 years [3].

  • Regulatory and Policy Environment:
    Legislation promoting biosimilar adoption and price transparency can compress margins. The Inflation Reduction Act and policies targeting drug price negotiation further influence pricing strategies.

  • Market Penetration and Clinical Adoption:
    Increased prescribing, expanded indications, and positive clinical data will support sustained or increased pricing power.

Projection Scenarios:

  • Conservative Scenario:
    In the absence of biosimilar competition, the drug maintains a premium price, with annual growth of 2-3%. Net price reductions due to rebates remain stable, and market share stabilizes at current levels.

  • Moderate Competition Scenario:
    With biosimilar entrants emerging within 3-5 years, a price reduction of 30% is projected. Market share may decline by approximately 15-20%, but overall revenue remains stable due to expanding patient demand.

  • Aggressive Competition Scenario:
    If multiple biosimilars penetrate quickly, with aggressive pricing strategies, prices could fall by 50% or more. Revenues would decline unless offset by increased market share or expanded indications.

Long-term Price Outlook:
Over the next 5 years, the average selling price (ASP) for this drug could decline by approximately 20-40%, considering biosimilar competition and policy measures, while overall market demand increases with broader indication approvals.


Revenue and Market Share Projections

Assumptions:

  • Current annual sales: Estimated at $500 million, contingent on market penetration and pricing.
  • Growth rate pre-biosimilar entry: 8-10% annually due to increased adoption.
  • Price reduction upon biosimilar introduction: 30-50% over 3-5 years.

Forecasts:

  • Year 1-2: Stable or slight growth; prices remain near peak levels, with revenue growth driven primarily by increased demand.
  • Year 3-5: Entry of biosimilars results in a significant price decrease, with revenue stabilizing or declining by 20-40% depending on market share retention.

Note: Actual numbers require specific sales data and market share details, which are often proprietary or not publicly disclosed for precise projections.


Regulatory and Policy Impact on Pricing

Regulatory decisions—such as FDA approval of biosimilars—directly impact pricing strategies. Legislation like the Biologics Price Competition and Innovation Act (BPCIA) fosters biosimilar development, accelerating price reductions. Additionally, Medicare and Medicaid price negotiation authority under recent policies could lower reimbursement levels, compressing margins further.

Key Challenges and Opportunities

  • Challenges:

    • Patent cliffs and biosimilar competition.
    • Pricing pressure from payers and regulators.
    • Potential for negative clinical data or safety concerns to impact demand.
  • Opportunities:

    • Expanded indications could grow the market.
    • Strategic partnerships may enhance market reach.
    • Differentiation through simplified administration or companion diagnostics.

Key Takeaways

  • The market for NDC 68180-0895 is inherently tied to its therapeutic class, regulatory status, and competitive landscape.
  • Current pricing strategies likely reflect high biologic list prices with significant rebates and discounts.
  • Market dynamics suggest a potential 20-40% price decline over the next 3-5 years due to biosimilar competition and legislative pressures.
  • Revenue projections must consider patent expiry timelines, evolving indications, and payer strategies.
  • Proactive market positioning involves investment in clinical data, indication expansion, and strategic partnerships to mitigate pricing erosion.

FAQs

Q1: How does biosimilar entry affect the price of NDC 68180-0895?
A1: Biosimilar entry typically leads to a 20-50% decrease in price over 3-5 years, driven by increased competition and payer negotiations, which reduce the original biologic's market share and profitability.

Q2: What factors influence the current price of this drug?
A2: Factors include the drug’s therapeutic class, manufacturing costs, patent protections, reimbursement negotiations, utilization rates, and competitive landscape.

Q3: Are there any upcoming regulatory changes that could impact pricing?
A3: Yes. Legislation enabling Medicare/Medicaid price negotiations and policies promoting biosimilar uptake could significantly reduce prices and margins in the near future.

Q4: How can companies optimize revenue amid pricing pressures?
A4: By expanding indications, improving clinical outcomes, fostering payer relationships, and innovating administration methods, companies can maintain or grow revenue despite declining prices.

Q5: What is the overall market outlook for biologic drugs like NDC 68180-0895?
A5: The biologics market remains robust, with growth driven by innovation, expanding indications, and high unmet medical needs. However, pricing pressure from biosimilars and policy reforms necessitate strategic adaptation to sustain profitability.


References

[1] IQVIA Institute. (2022). The Growing Value of Biologics.
[2] Centers for Medicare & Medicaid Services. (2021). Report on Drug Pricing Trends.
[3] EvaluatePharma. (2022). Biosimilar Market Trends.

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