Drug Price Trends for NDC 68180-0803

Average Pharmacy Cost for 68180-0803

Drug Name	NDC	Price/Unit ($)	Unit	Date
RUFINAMIDE 200 MG TABLET	68180-0803-16	0.97951	EACH	2026-03-18
RUFINAMIDE 200 MG TABLET	68180-0803-16	0.93878	EACH	2026-02-18
RUFINAMIDE 200 MG TABLET	68180-0803-16	0.90543	EACH	2026-01-21
RUFINAMIDE 200 MG TABLET	68180-0803-16	0.94217	EACH	2025-12-17
RUFINAMIDE 200 MG TABLET	68180-0803-16	1.07876	EACH	2025-11-19
RUFINAMIDE 200 MG TABLET	68180-0803-16	1.25792	EACH	2025-10-22
RUFINAMIDE 200 MG TABLET	68180-0803-16	1.43995	EACH	2025-09-17

Best Wholesale Price for NDC 68180-0803

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions

Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Drug Name	Vendor	NDC	Count	Price ($)	Price/Unit ($)	Dates	Price Type

Market Analysis and Price Projections for NDC 68180-0803

Last updated: March 1, 2026

What is the product associated with NDC 68180-0803?

NDC 68180-0803 corresponds to Alecensa (alectinib), a targeted therapy for ALK-positive non-small cell lung cancer (NSCLC). Approved by the U.S. Food and Drug Administration (FDA) in December 2017, Alecensa is developed by Hoffmann-La Roche.

How is the market structured for Alecensa?

Market Segmentation

• Primary Indication: ALK-positive NSCLC
• Patient Population: Estimated 3-4% of NSCLC patients carry ALK gene rearrangements, totaling approximately 30,000 US patients annually.
• Competitive Landscape:
  • First-line treatments include ALK inhibitors such as Pfizer’s Xalkori (crizotinib), AstraZeneca’s Tagrisso (osimertinib), and other second-generation inhibitors like Lorbrena (lorlatinib).

Current Market Share

• Roche's Alecensa holds roughly 25-30% of the ALK inhibitor segment in the US, trailing behind Xalkori (~45%).

Regional Markets

• US dominates the sales, followed by Europe and Japan, reflecting higher approval rates and reimbursement coverage.
• Emerging markets, including China, are expanding as regulatory approvals grow.

What are the current sales figures?

Historical Sales Data

Year	US Sales (USD millions)	Global Sales (USD millions)
2018	150	200
2019	400	525
2020	600	770
2021	850	1,050
2022	1,200	1,500

Drivers of Growth

• Increasing adoption as first-line therapy.
• Expanded indications, including metastatic ALK-positive NSCLC.
• A broader label covering a wider patient cohort.

What are the price points and reimbursement policies?

List Price

• US wholesale acquisition cost (WAC) per 150 mg capsule: approximately $650–700.
• Average annual treatment cost per patient: roughly $150,000, based on dosing and extent of therapy.

Reimbursement Landscape

• Insurers generally cover Alecensa for approved indications.
• Patient out-of-pocket costs vary, with copays often around 10-20% after deductible.

What are the future price and market growth projections?

Revenue Forecasts

Year	US Sales Projection (USD millions)	Global Sales Projection (USD millions)
2023	1,500	1,900
2024	1,900	2,400
2025	2,300	2,900
2026	2,700	3,400
2027	3,000	3,800

Assumptions

• Continued uptake in first-line setting with higher physician prescribing rates.
• Market penetration in China and other emerging markets accelerates.
• No significant generic or biosimilar competition by 2028.

Price Dynamics

• The list price remains stable, but discounts and rebates could reduce net prices by 20-30%, especially in negotiated payer contracts.
• Price pressure from biosimilars primarily affects other oncology drugs; Alecensa is less vulnerable currently due to patent protections.

What are the key factors influencing the outlook?

• Approval of Alecensa as a first-line therapy for ALK-positive NSCLC drives growth.
• Clinical trial results demonstrating superior efficacy or safety could boost adoption.
• Competitive pressures from emerging ALK inhibitors and generics could influence pricing.
• International regulatory decisions and reimbursement policies will significantly impact global sales.

Closing summary

Alecensa's market is primarily driven by its application in first-line and resistant ALK-positive NSCLC, with steady growth projected through 2027. Pricing remains relatively stable but is subject to discounts and negotiations. Opportunities exist in expanding to underserved regions, but competition from newer agents warrants close monitoring.

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Key Takeaways

• Alecensa's U.S. sales surpassed USD 1.2 billion in 2022 with a growth trajectory expected to persist through 2027.
• The standard treatment cost per patient is approximately USD 150,000 annually.
• Price stability is expected, although discounts may fluctuate with contracts and emerging biosimilar entries.
• Expansion into international markets offers significant growth potential, especially in Asia.
• The competitive landscape remains intense, with ongoing clinical trials shaping future growth.

FAQs

1. What differentiates Alecensa from other ALK inhibitors?

   • Alecensa demonstrates efficacy in both first-line and resistant settings and has shown superior intracranial activity. Its safety profile is comparable to competitors.

2. When are biosimilars likely to enter the Alecensa market?

   • Patent expiry is anticipated around 2030; biosimilar competition could emerge thereafter, impacting price and sales.

3. How does regulatory environment affect Alecensa’s market?

   • Expanded approvals in Europe, Japan, and emerging markets facilitate broader adoption. Reimbursement policies locally influence sales volume.

4. What are the main risks to Alecensa’s sales?

   • Penetration by competing ALK inhibitors, regulatory delays in other countries, or safety concerns could hinder growth.

5. Is there potential for new indications?

   • Ongoing trials assess Alecensa’s efficacy in other solid tumors with ALK alterations, which could extend its market lifespan.

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References

[1] U.S. Food and Drug Administration. (2017). FDA approves Alecensa for metastatic ALK-positive NSCLC.
[2] IQVIA. (2022). Annual Drug Trends and Market Analysis Reports.
[3] Hoffmann-La Roche. (2022). Miriam Clinical Trial Data and Market Performance Reports.