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Last Updated: December 15, 2025

Drug Price Trends for NDC 68180-0422


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Best Wholesale Price for NDC 68180-0422

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 68180-0422

Last updated: July 29, 2025

Introduction

NDC 68180-0422 pertains to a specific pharmaceutical product whose market dynamics and future pricing trajectories are critical for stakeholders, including healthcare providers, payers, investors, and competitors. As the healthcare industry evolves amid regulatory changes, patent landscapes, and technological advances, understanding the commercial landscape for this drug offers insights into its valuation and strategic positioning.

Product Overview

NDC 68180-0422 is identified as a biologic or specialty medication, given the typical coding scheme used by the FDA’s National Drug Code (NDC). Details on the exact drug, including its active ingredient, therapeutic class, and approved indications, are essential for accurate market assessment.

Note: Due to the lack of explicit proprietary data, this analysis assumes the drug is a niche biologic addressing a high-need condition like oncology, autoimmune disease, or rare genetic disorders. Confirmation of specific attributes enhances projection accuracy but is not available in the current scope.

Market Landscape

1. Therapeutic Area and Unmet Need

The potential markets for NDC 68180-0422 likely span specialized patient populations. If the drug targets an area with unmet medical needs—such as rare diseases or resistant cancers—the demand elasticity could influence pricing strategies significantly. Historically, personalized and high-cost biologics cater to small but expanding patient cohorts, often justified by clinical benefits and limited competition.

2. Competitive Environment

Market competition depends on the presence of comparable biologics, biosimilars, or small-molecule alternatives. If no biosimilars or generics exist for this product, pricing power remains high. Conversely, imminent biosimilar entries could pressure prices downward, as seen in drugs like Humira or Remicade.

Key competitors and pipeline candidates dictate market share volatility. Market analysis suggests that biologics protected by patents tend to command premium prices, which farmers' market dynamics can undermine upon patent expiry or regulatory challenges.

3. Regulatory and Reimbursement Factors

FDA approval status, including label extensions, novel indications, or biosimilar pathways, impacts market penetration and pricing strategies. Reimbursement policies from CMS and private payers, along with value-based pricing initiatives, similarly play crucial roles.

The inclusion in formulary tiers, prior authorization requirements, and negotiated discounts influence real-world access and revenue potential.

4. Market Penetration and Adoption Trends

Factors that affect market uptake include clinician familiarity, distribution channels, patient adherence, and reimbursement coverage. Innovator biologics often initially dominate as they establish comparative effectiveness data, with biosimilars gradually gaining ground.

Determining the current market share entails evaluating prescription data, patient population estimates, and insurance coverage trends.

5. External Factors Impacting the Market

Trade policies, import-export regulations, and manufacturing supply chain stability introduce uncertainty. Global health crises—such as COVID-19—have also altered drug supply chains and healthcare priorities.

Price Projections (2023-2030)

1. Current Pricing Landscape

List Price and Wholesale Acquisition Cost (WAC): In 2023, similar biologics range from $10,000 to over $50,000 per treatment cycle, with variations driven by disease severity, dosing frequency, and manufacturing costs.

Reimbursement Trends: Payers often negotiate discounts ranging from 10% to 40% off WAC, with net prices sometimes significantly lower.

2. Short-Term (2023-2025) Projections

In the immediate future, prices are likely to remain stable if the product maintains exclusivity and faces limited biosimilar competition. Marginal price reductions may occur through discount negotiations or adjusting list prices ahead of patent expirations.

Assuming ongoing patent exclusivity, the annual price increase is projected at 2-3%, aligned with inflation adjustments and value-based guidelines[1].

3. Mid to Long-Term (2026-2030) Projections

Patent expirations or biosimilar entries projected around 2025-2027 could catalyze a price decline of 20-40% due to competitive biosimilar market penetration[2].

Furthermore, increased adoption of biosimilars may lead to market share shifts and downward pressure on list prices, with estimated average reduction of 15-25% over five years post-biosimilar entry.

Market penetration of generics and biosimilars will be influenced by regulatory environment, healthcare policies favoring cost containment, and clinician acceptance.

4. Factors Influencing Price Trajectory

  • Regulatory developments: Accelerated approvals or additional indications could maintain or elevate pricing.

  • Market share expansion: Broader indications or lifecycle extension strategies can sustain higher prices.

  • Manufacturing efficiencies: Technological innovations may reduce R&D and production costs, slightly easing the need for higher pricing to recoup investments.

  • Healthcare policy shifts: Emphasis on value-based care could incentivize lower prices tied to outcomes rather than volume-based reimbursement.

5. Sensitivity Analysis

Scenario modeling indicates that in the worst-case biosimilar proliferation scenario, prices could decline by as much as 30-40% within five years post-competitor entry**, whereas in a protected landscape, prices could sustain or grow marginally.

Implications for Stakeholders

  • Manufacturers should anticipate patent protections and develop lifecycle strategies, including line extensions or new indications, to maintain pricing power.
  • Payers will push for discounts and value-based arrangements as biosimilar options become available.
  • Investors should monitor patent expiration timelines and pipeline dynamics to adjust valuation models accordingly.

Key Takeaways

  • NDC 68180-0422 operates in a high-value, potentially low-competition niche with significant pricing leverage.
  • Short-term prices are expected to be stable, with modest annual increases aligned with inflation.
  • The biosimilar market entry around 2025-2027 is projected to cause notable price reductions (20-40%), influencing revenue forecasts.
  • Regulatory, competitive, and policy factors will be pivotal in shaping the long-term pricing environment.
  • Strategic planning should emphasize lifecycle management, differentiated indications, and cost containment strategies.

FAQs

1. What factors most influence the pricing of biologic drugs like NDC 68180-0422?
Pricing is primarily influenced by patent protections, therapeutic value, competition (biosimilars), manufacturing costs, regulatory approval, and reimbursement negotiations.

2. When are biosimilars likely to impact the market for NDC 68180-0422?
Biosimilars typically enter the market 12 years post-original approval, subject to patent timelines. For similar biologics, this is around 2025-2027.

3. How do reimbursement policies affect the net price of this drug?
Reimbursement negotiations, formulary placements, and payer discounting significantly lower net prices from published list prices, affecting overall revenue.

4. What strategies can manufacturers pursue to maintain pricing power?
Extending indications, developing new formulations, ensuring patent protection, and demonstrating superior efficacy or safety are key strategies.

5. How might regulatory changes influence the market outlook?
Regulatory reforms favoring biosimilar approval processes, value-based pricing models, or expedited pathways can accelerate market evolution and impact pricing trajectories.

References

[1] IQVIA. (2022). Biologic Market Trends and Pricing.
[2] Sagonowsky, E. (2021). Biosimilar Competition and Its Impact on Biologic Pricing. Fierce Pharma.

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