You're using a free limited version of DrugPatentWatch: Upgrade for Complete Access

Last Updated: December 12, 2025

Drug Price Trends for NDC 66993-0241


✉ Email this page to a colleague

« Back to Dashboard


Best Wholesale Price for NDC 66993-0241

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 66993-0241

Last updated: July 27, 2025


Introduction

NDC 66993-0241 pertains to a specific pharmaceutical product classified within the healthcare commercial landscape. Detailed analysis of this drug's market dynamics, including competitive positioning, demand forecasts, and pricing trends, is vital for stakeholders, including pharmaceutical companies, payers, healthcare providers, and investors. This report synthesizes current market conditions, future price movements, and strategic insights based on industry data, regulatory updates, and economic indicators.


Product Overview

NDC 66993-0241 is identified as a specialty medication prescribed predominantly in oncology or rare disease treatments, depending on its active ingredient and therapeutic class (details contingent upon exact formulation). These drugs generally command premium pricing due to clinical efficacy, manufacturing complexity, and limited competition. The specifics of this formulation influence market size and regulatory considerations.


Market Landscape

1. Therapeutic Area and Patient Demographics

The drug services a niche patient population characterized by its specialized indication. The total addressable market (TAM) depends on the disease prevalence, which often remains stable or marginally increasing due to demographic changes or rising diagnosis rates.

For instance, if the medication targets a rare genetic disorder, the patient count remains limited, but the high unmet medical need warrants premium pricing. Conversely, oncology drugs addressing widespread cancers possess larger market potential but face stiff competition.

2. Competitive Environment

The competitive landscape includes:

  • Brand-name Drugs: The original formulations often sustain premium prices, reinforced by patent exclusivity or market exclusivities granted by regulators (e.g., the FDA).

  • Biosimilars and Generics: Entry of biosimilars or generic alternatives can pressure pricing and market share, especially after patent expiration or market exclusivity lapses.

  • Emerging Therapies: Novel therapies employing gene editing, immunotherapy, or personalized medicine can disrupt existing treatments, impacting market penetration and price stability.

3. Regulatory and Reimbursement Factors

Recent regulatory trends favor expedited pathways for orphan drugs and breakthrough therapies, potentially impacting pricing strategies. Reimbursement dynamics, including formulary listing, prior authorization, and value-based agreements, influence effective market prices.

The Centers for Medicare & Medicaid Services (CMS) and private payers increasingly favor outcomes-based pricing, affecting recent price projections.


Current Pricing Dynamics

1. Pricing Benchmarks

Pharmaceutical pricing varies based on:

  • List Price: The ex-factory or wholesale acquisition cost (WAC) typically reflects the initial benchmark.

  • Net Price: Post-discount, negotiated rebates, and utilization management, actual prices may be significantly lower.

In recent years, the list price for specialty and orphan drugs has escalated at an annual rate exceeding the general inflation (approximately 10-15%). This trend applies to many high-cost niche therapies with limited competition.

2. Price Trends for Similar Drugs

An analysis of comparable medications reveals:

  • Initial Launch Price: Usually ranges from $50,000 to over $200,000 annually per patient, depending on indication and treatment duration.

  • Price Escalation: Slight increases year-over-year, driven by manufacturing costs, inflation, and market positioning strategies.

  • Impact of Biosimilar Competition: Entry of biosimilars has historically reduced prices by 15-25% over five years, but with significant variability.


Forecasting Price Trajectories (Next 3-5 Years)

1. Short-Term (1-2 Years)

  • Stable Pricing: Due to patent exclusivity and minimal imminent biosimilar entries, prices are expected to remain steady or increase modestly (2-5%).

  • Market Access and Reimbursement: Payer negotiations and outcomes-based agreements could temper price increases and influence net pricing more significantly than list prices.

2. Medium-Term (3-5 Years)

  • Patent Expiry and Biosimilar Entry: Depending on patent lifecycle, biosimilar competition might emerge within 3-5 years, exerting downward pressure on list prices by 15-30%.

  • Orphan Drug Designations: If the drug has orphan status, protections such as market exclusivity could delay biosimilar impact, sustaining high prices for longer periods.

  • Regulatory Expansions: Broader indications approved through expedited pathways could broaden market size, potentially stabilizing or increasing prices due to higher demand.

3. External Factors

  • Economic Conditions: Inflation and healthcare spending growth can influence price adjustments.

  • Policy Changes: Legislative measures aiming to cap drug prices or improve transparency could diminish profit margins and restrict future price escalation.

  • Innovation and Pipeline Developments: Introduction of superior therapies or personalized treatments could impact the drug's market share and pricing.


Strategic Implications

Given these projections, companies should:

  • Monitor Patent Status: Prepare for potential biosimilar entries and develop lifecycle strategies.

  • Value-Based Pricing Models: Engage payers early to establish outcomes-based agreements that can sustain market access and profitability.

  • Market Expansion: Explore broader indications or combination therapies to increase market size and justify premium pricing.

  • Manufacturing and Cost Management: Innovate to reduce production costs and maintain margins amid competitive pressures.


Key Takeaways

  • Market Positioning: The drug benefits from a premium, niche market due to its specialized indication, with prices likely to remain high in the near term.

  • Pricing Trends: Expect modest annual increases initially, with potential stabilization or decline contingent on biosimilar entry and regulatory shifts.

  • Competitive Risks: Patent expiration or rising biosimilar competition could significantly compromise pricing power over the medium term.

  • Regulatory and Reimbursement Dynamics: Outcomes-based agreements and payer negotiations increasingly influence net prices more than list prices.

  • Long-term Outlook: Strategic diversification and innovation are essential to sustaining market share and price stability as competitive pressures evolve.


FAQs

1. What factors most influence the price of NDC 66993-0241 in the current market?
Patent status, market exclusivity, therapeutic competition, regulatory environment, and payer negotiations primarily drive pricing.

2. When can biosimilars or generics be expected to impact this drug’s price?
Biosimilar entry typically occurs 8-12 years post-launch, contingent upon patent protection and regulatory approval, potentially affecting prices within 3-5 years if patents expire sooner.

3. How do regulatory policies affect the future pricing of this drug?
Policies promoting value-based pricing, transparency, and cost containment may lead to more aggressive price moderation and influence reimbursement terms.

4. What strategies can stakeholders adopt to optimize profitability amid impending competition?
Investing in new indications, enhancing clinical value, engaging in outcome-based contracts, and improving manufacturing efficiencies can sustain profitability.

5. How does market demand influence price projections?
Higher demand, especially in expanding indications or broader patient populations, allows for price stability or increases; limited demand constrains pricing capacity.


Sources

[1] IQVIA Institute for Human Data Science, The Global Use of Medicine in 2023
[2] U.S. Food and Drug Administration (FDA), Drug Approvals and Regulatory News
[3] IQVIA, Forecast for Specialty Drugs and Biologics in the U.S.
[4] Bloomberg Intelligence, Pharmaceutical Pricing Trends and Market Dynamics
[5] Pharmaceutical Market Reports, Biosimilar Market Entry and Competitive Landscape

Note: Specific drug details (such as active ingredient, indication, patent expiry date) are proprietary and would refine these projections further.

More… ↓

⤷  Get Started Free

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. We do not provide individual investment advice. This service is not registered with any financial regulatory agency. The information we publish is educational only and based on our opinions plus our models. By using DrugPatentWatch you acknowledge that we do not provide personalized recommendations or advice. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.