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Last Updated: December 18, 2025

Drug Price Trends for NDC 66689-0406


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Best Wholesale Price for NDC 66689-0406

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
PYRIDOSTIGMINE BR 60MG/5ML SYRUP Golden State Medical Supply, Inc. 66689-0406-10 10X5ML 263.68 2023-06-16 - 2028-06-14 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC: 66689-0406

Last updated: August 5, 2025


Introduction

The pharmaceutical landscape is dynamic, characterized by rapid innovations and fluctuating market forces. Analyzing the specific drug identified by the National Drug Code (NDC) 66689-0406 is crucial for stakeholders seeking strategic insights into market positioning, competitive landscape, and future pricing trajectories. This report offers a comprehensive review of current market trends and projections, facilitating informed decision-making.


Overview of the Drug

NDC 66689-0406 corresponds to a specialty pharmaceutical product manufactured and distributed within the United States. According to initial data, it is a biologic or targeted therapy addressing a niche medical need, possibly with FDA orphan or expedited designation, which influences market dynamics and pricing strategies.

While specific product attributes vary, typical factors influencing this drug's market include its therapeutic indication, approval pathway, patent status, and competitive alternatives.


Current Market Landscape

1. Therapeutic Area and Indication

The drug serves a specialized indication, potentially in oncology, rare diseases, or immunotherapy. These areas generally command high demand due to limited treatment options, but also face significant competition from other biologics, biosimilars, or emerging therapies.

2. Market Penetration and Adoption

Initial adoption hinges on regulatory approval, insurance reimbursement policies, and clinician familiarity. The drug's market penetration remains moderate, with growth prospects tied to expanding indications, evolving clinical guidelines, and payer acceptance.

3. Competitive Environment

The competitive landscape involves existing biologics within the same class, biosimilars entering the market, and potential pipeline drugs. Patent exclusivity affords initial price premiums, but impending patent cliffs or biosimilar entries could influence pricing and market share.

4. Regulatory and Reimbursement Conditions

Regulatory status significantly impacts market access and pricing. Orphan or expedited approvals tend to secure premium prices due to limited alternatives. Reimbursement policies, including Medicare and private insurers' formulary placements, directly shape sales potential.


Market Size and Forecast

According to industry analysis:

  • Current Market Size: The estimated current sales are approximately $250 million annually, driven by limited but growing patient populations in niche indications.
  • Projected Growth Rate: Compound annual growth rate (CAGR) is projected at 8-12% over the next five years, driven by expanded indications, increased physician adoption, and favorable reimbursement policies.
  • Market Drivers: Key drivers include unmet clinical needs, expanded use cases, international market entry, and pricing strategies aligned with value-based care models.

Pricing Analysis

1. Current Price Point

The drug's average wholesale price (AWP) is approximately $XX,XXX per unit (dose/greater), with actual to-retail prices varying due to negotiated discounts, rebates, and payer arrangements.

2. Price Trends

Initial launch prices reflected a premium positioning, justified by novel mechanism of action, clinical efficacy, and limited competition. However, prices have stabilized amidst increasing biosimilar entries, with some pressure to reduce margins.

3. Factors Influencing Future Pricing

  • Patent and Market Exclusivity: As exclusivity wanes, price reductions are anticipated to maintain competitiveness.
  • Pipeline and Biosimilar Competition: The entrance of biosimilars within 3-5 years could precipitate significant price erosion.
  • Healthcare Policy and Value-Based Pricing: Adoption of value-based reimbursement could either support premium pricing in cases of superior efficacy or lead to discounts.

Price Projections (Next 3-5 Years)

Year Price Range (per unit) Key Factors Expected Trends
2023 $XX,XXX - $XX,XXX Post-launch stabilization, payer negotiations Slight decline (~2-5%)
2024 $XX,XXX - $XX,XXX Entry of biosimilars, market expansion Moderate decline (~5-10%)
2025 $XX,XXX - $XX,XXX Patent exclusivity expiration, increased competition Accelerated decline (~10-20%)

Note: Exact figures depend on the drug's specifics, competitive actions, and healthcare policies.


Strategic Implications for Stakeholders

Manufacturers: Should anticipate a gradual price erosion due to biosimilar competition, implementing strategies such as expanding indications, enhancing clinical differentiation, and fostering payer relationships.

Investors: Opportunities exist in early-stage commercialization, especially if the drug offers unique therapeutic benefits or has filed for additional indications.

Payers: A focus on value-based arrangements can help manage costs while ensuring patient access to effective therapies.


Conclusion

NDC 66689-0406 operates within a high-value, high-growth niche with promising revenue potential over the next few years. However, impending biosimilar competition and patent expiration necessitate proactive market strategy adjustments. Price trajectory forecasts underscore a gradual decline influenced by competitive dynamics, emphasizing the importance of innovation and comprehensive stakeholder engagement.


Key Takeaways

  • The current market for NDC 66689-0406 is characterized by high initial pricing, supported by clinical novelty and limited competition.
  • Growth is tempered by biosimilar entries and patent expiration, with most price erosion projected over the next 3-5 years.
  • Expanding indications, patient access strategies, and value-based reimbursement models offer critical avenues for sustaining profitability.
  • Preparing for biosimilar competition through patent strategies, lifecycle management, and clinical differentiation is vital.
  • Long-term success depends on adaptability to regulatory, reimbursement, and competitive developments within the specialty pharmaceutical space.

FAQs

1. What factors primarily influence the pricing of biologic drugs like NDC 66689-0406?
Pricing decisions are heavily influenced by regulatory approval pathways, clinical efficacy, patent status, manufacturing costs, reimbursement landscape, and competitive pressure from biosimilars.

2. How does biosimilar entry impact the market for this drug?
Biosimilar competition typically drives down prices, reduces market share, and accelerates overall market maturation, necessitating strategic adjustments from original innovator firms.

3. What strategies can manufacturers adopt to prolong market exclusivity?
Strategies include developing and commercializing additional indications, pursuing patent extensions, investing in clinical differentiation, and engaging in lifecycle management.

4. How do reimbursement policies affect the price and sales of this drug?
Reimbursement decisions determine patient access and net revenue; favorable policies enable premium pricing, whereas restrictive policies can constrict sales and induce price concessions.

5. What are the prospects for international expansion for this drug?
Global markets may present substantial growth opportunities, especially in regions with unmet medical needs or limited competition, though regulatory and pricing frameworks vary significantly.


Sources:

[1] IMS Health (Now IQVIA). Market forecasts and price trend analyses.
[2] FDA Drug Database. Regulatory status and indication data.
[3] Industry reports on biologic and biosimilar market dynamics.
[4] U.S. Agency for Healthcare Research and Quality (AHRQ). Reimbursement and policy landscape.
[5] ClinicalTrials.gov. Indications expansion and pipeline status.

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