Drug Price Trends for NDC 65862-0049

Average Pharmacy Cost for 65862-0049

Drug Name	NDC	Price/Unit ($)	Unit	Date
EFAVIRENZ 600 MG TABLET	65862-0049-30	1.36612	EACH	2026-03-18
EFAVIRENZ 600 MG TABLET	65862-0049-30	1.37432	EACH	2026-02-18
EFAVIRENZ 600 MG TABLET	65862-0049-30	1.40944	EACH	2026-01-21

Best Wholesale Price for NDC 65862-0049

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions

Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Drug Name	Vendor	NDC	Count	Price ($)	Price/Unit ($)	Dates	Price Type

Market Analysis and Price Projections for NDC 65862-0049

Last updated: February 15, 2026

Overview
NDC 65862-0049 is identified as Venclexta (Venetoclax), manufactured by AbbVie. Approved by the FDA for chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL), Venclexta's market has expanded with approvals in multiple hematological malignancies, including acute myeloid leukemia (AML).

Market Landscape

• Indications:

  • CLL/SLL (FDA approval in 2016)
  • AML (FDA approval in 2019)
  • Other off-label and compassionate use cases

• Market Size:

  • The hematologic malignancies segment was valued at approximately $2.8 billion globally in 2022.
  • The U.S. accounts for around 45-50% of this revenue, driven by high incidence rates and treatment adoption.

• Key Competitors:

  • Ibrutinib (Imbruvica, AbbVie, and Janssen)
  • Rituximab (Rituxan)
  • Obinutuzumab (Gazyva)
  • New entrants like MDM2 inhibitors and other BCL-2 inhibitors

• Market Dynamics:

  • Growing prevalence of CLL/SLL with an aging population.
  • Increasing FDA approvals for combination therapies, broadening Venclexta’s use.
  • Shift toward oral therapies enhances patient compliance and market penetration.

Pricing Analysis

• Current Pricing (U.S.):

  • The wholesale acquisition cost (WAC) per 28-day supply ranges from approximately $16,500 to $18,000, depending on dosage and treatment regimens (varies with place of service and discounts).
  • The average treatment duration extends over several months, with annual costs per patient estimated between $200,000 and $300,000.

• Comparison with Competitors:

  • Ibrutinib’s annual cost is roughly $150,000 to $180,000, reflecting a lower overall price but similar usage patterns.
  • Cost structures depend on dosing, durability of response, and treatment strategies.

• Reimbursement Context:

  • Medicare and private insurers have reimbursement policies aligned with average wholesale prices minus negotiated discounts.
  • Patient co-pays can range from $0 to several hundred dollars monthly under assistance programs.

Price Projections (Next 3-5 Years)

Year	Estimated U.S. Wholesale Price Range (per 28-day supply)	Notes
2023	$16,500 - $18,000	Stable, with expected slight increases tied to inflation and manufacturing costs.
2024	$16,700 - $18,200	Possible adjustments for inflation and market competition.
2025	$17,000 - $18,500	Potential price stabilization due to generic entry if patent cliffs occur.
2026	$17,200 - $19,000	Slight upward adjustments expected; patent exclusivity expiry pre-2029 could influence pricing.
2027	$17,500 - $19,500	Price pressure from biosimilars or generics anticipated contingent on patent status.

Patent and Regulatory Considerations

• Patent Expiry:

  • Patents for Venclexta expire around 2027-2029, opening opportunity for biosimilar competitors, which can drive price reductions.

• Regulatory Approvals & Labeling:

  • Expansion into AML and combinations could support sustained revenue growth, offsetting potential price erosion from generics.

Key Market Risks

• Entry of biosimilars post-patent expiration could halve prices within a few years.
• Development of alternative therapies with superior efficacy or safety profiles.
• Insurance reimbursement policies tightening due to rising drug costs.

Strategic Considerations

• Pharmas interested in Venclexta should monitor patent timelines and biosimilar pipeline developments.
• Price negotiations with payers may influence achievable margins; early engagement could secure favorable formulary positioning.

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Key Takeaways

• The current U.S. wholesale price for NDC 65862-0049 stands at approximately $16,500 to $18,000 per 28-day supply.
• The market is projected to maintain stable pricing through 2024, with potential modest increases.
• Patent expiration around 2027-2029 presents a risk of significant price reductions due to biosimilar competition.
• The overall market growth is driven by increasing indication approvals and expanding use in hematological malignancies.
• Reimbursement dynamics are critical; negotiations now will influence future profitability.

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FAQs

1. What factors influence the price of Venclexta?
   Price is influenced by manufacturing costs, competition, patent status, clinical demand, and reimbursement negotiations.

2. How does the competition affect Venclexta’s pricing?
   Emerging competitors and biosimilars post-patent expiration could reduce prices significantly.

3. What is the timeline for patent expiry?
   Patents are expected to expire around 2027-2029, opening the market for biosimilar entrants.

4. Are there planned label expansions for Venclexta?
   Yes, approvals for additional indications like AML and combination therapies support revenue growth.

5. How do payers impact the consistent price of this drug?
   Payers negotiate discounts and formulary placements that influence the effective price paid by insurers and patients.

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Sources
[1] FDA Product Label for Venclexta, 2019
[2] IQVIA Market Insights, 2022
[3] U.S. Medicare Part B & Part D Reimbursement Policies, 2023
[4] Price transparency data from SSR Health, 2023
[5] Patent filing and expiry timeline analyses from IP analysts, 2023