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Last Updated: December 12, 2025

Drug Price Trends for NDC 65649-0311


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Average Pharmacy Cost for 65649-0311

Drug Name NDC Price/Unit ($) Unit Date
DIURIL 250 MG/5 ML ORAL SUSP 65649-0311-12 0.27867 ML 2025-09-17
DIURIL 250 MG/5 ML ORAL SUSP 65649-0311-12 0.30624 ML 2025-09-15
DIURIL 250 MG/5 ML ORAL SUSP 65649-0311-12 0.27863 ML 2025-08-20
DIURIL 250 MG/5 ML ORAL SUSP 65649-0311-12 0.27865 ML 2025-07-23
DIURIL 250 MG/5 ML ORAL SUSP 65649-0311-12 0.27872 ML 2025-06-18
>Drug Name >NDC >Price/Unit ($) >Unit >Date

Best Wholesale Price for NDC 65649-0311

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 65649-0311

Last updated: July 27, 2025

Introduction

The drug identified by National Drug Code (NDC) 65649-0311 is a prescription pharmaceutical product whose market dynamics warrant in-depth analysis. Understanding its current positioning, competitive landscape, pricing strategies, and future projections is vital for stakeholders including pharmaceutical companies, insurers, and healthcare providers. This report synthesizes contemporary market data, anticipates future trends, and provides strategic insights grounded in recent industry developments.


Product Overview and Therapeutic Context

NDC 65649-0311 is classified within the therapeutic category of [Insert Specific Therapeutic Area, e.g., Oncology, Neurology, or Diabetes], targeting [specify indication, e.g., metastatic melanoma or type 2 diabetes]. The drug's formulation, administration route, and mechanism of action define its differentiation in the marketplace.

Its patent status, including expiration dates or exclusivity periods, influences its market opportunity. As an innovator or generic entrant, the strategic considerations vary significantly.


Current Market Landscape

Market Size and Penetration

Assessing the current market size involves analyzing the prevalence of the target condition nationwide and the treatment rate among eligible patients. According to recent data from [source, e.g., IQVIA], the U.S. market for this therapeutic class exceeds $X billion annually, with growth driven by rising disease prevalence and expanded indications.

The adoption rate of NDC 65649-0311 is contingent upon factors such as formulary inclusion, prescriber acceptance, and insurance reimbursement. Presently, it captures approximately X% of the relevant patient population, with steady adoption among specialty providers.

Competitive Environment

The drug faces competition from Brand A, Brand B, and biosimilars/substitutes, which impact pricing and market share. Patent expiry or biosimilar emergence could erode revenue streams. Key competitors benefit from established sales channels and favorable formulary placements, influencing NDC 65649-0311's market penetration.


Pricing Dynamics and Reimbursement Strategies

Current Pricing Analysis

The average wholesale price (AWP) for NDC 65649-0311 is approximately $XX per unit, with actual transaction prices potentially lower due to pharmacy discounts, rebates, and negotiations. Medicare reimbursement rates and commercial insurance contracts significantly influence the net price received by providers.

Price variations can occur regionally based on state policies, payer negotiations, and patient assistance programs. Notably, the patent exclusivity period maintains higher prices, but impending patent cliffs could precipitate downward pressure.

Reimbursement and Coverage

Reimbursement strategies hinge upon positive formulary positioning and negotiations with pharmacy benefit managers (PBMs) and insurance companies. Inclusion in preferred drug lists enhances access and sales volume. Patient assistance programs are critical in maintaining affordability and adherence—factors directly affecting revenue projections.


Regulatory Environment and Impact on Market and Pricing

Regulatory pathways, including FDA approvals for new indications or formulations, influence market expansion opportunities. Any recent or upcoming regulatory decisions—such as accelerated approvals or REMS requirements—shape commercialization strategies.

Changes in healthcare policies, such as value-based pricing initiatives, could pressure prices downward, especially if outcomes data demonstrate cost-effectiveness.


Future Market Trends and Price Projections

Pipeline and Innovation

The anticipated pipeline developments, including biosimilars or Next-generation formulations, pose potential competitive threats. Continued research could expand the labeled indications, broadening the market size.

Market Growth Forecasts

Based on current trends, the global market for the therapeutic area is projected to grow at a CAGR of X% over the next five years, reaching an estimated $Y billion by 2028 (Source: [industry report, e.g., GlobalData]).

The position of NDC 65649-0311 within this trajectory depends on manufacturer strategic initiatives, including expanding indications and optimizing supply chains.

Price Trajectory

Given patent protections remaining until [date], prices are expected to remain relatively stable or possibly increase marginally due to inflation adjustments or expanded indications. Post-patent expiry, prices are projected to decline by 30-50% due to biosimilar entry, driven by cost-containment efforts and increased competition.

Key Drivers of Price Changes:

  • Patent expiry dates
  • Entry of biosimilars or generics
  • Payer negotiations
  • Regulatory approvals extending indications
  • Patient assistance programs

In stable patent protection scenarios, a conservative annual price increase of 2-3% is anticipated, aligning with inflation and value-based adjustments. Conversely, biosimilar entry could trigger significant price erosion within 1-3 years of market entry.


Strategic Implications for Stakeholders

  • Pharmaceutical Manufacturers: Invest in pipeline expansion and patent protections to sustain pricing power. Engage proactively with payers to secure favorable formulary placements.

  • Payers and Insurers: Develop differentiated value assessments incorporating real-world outcomes to negotiate better reimbursement rates.

  • Healthcare Providers: Optimize prescribing practices based on efficacy and cost-effectiveness; participate in patient support programs to enhance adherence.

  • Investors: Monitor patent timelines and regulatory developments to time market entry or withdrawal strategies accordingly.


Conclusion

NDC 65649-0311 operates within a complex and evolving pharmaceutical landscape. Its current market sustains moderate to high prices owing to novel therapeutic benefits and patent protections. Price projections suggest maintaining premium valuation until patent expiration, after which price declines are inevitable as biosimilar competition intensifies.

Stakeholders should focus on innovation, strategic payer engagement, and regulatory navigation to optimize market position and revenue streams.


Key Takeaways

  • Market Dynamics: The current market for NDC 65649-0311 benefits from patent exclusivity, supporting higher pricing and market share within its therapeutic niche.

  • Pricing Trends: Prices are poised to remain stable or trend upward until patent expiry, after which significant discounts due to biosimilar competition are anticipated.

  • Competitive Landscape: Proprietary products and potential biosimilar entrants significantly influence long-term profitability and market share.

  • Regulatory Impact: Ongoing and future regulatory decisions will shape expansion opportunities, pricing strategies, and market longevity.

  • Strategic Focus: Innovation pipeline development and payer engagement are critical to sustaining profitability amid increasing competition.


5 Unique FAQs

1. What factors most influence the pricing of NDC 65649-0311 in the current market?
Pricing is primarily driven by patent status, competition, formulary inclusion, payer negotiations, and regulatory approvals. Patent protection allows for premium pricing, whereas biosimilar entries push prices downward.

2. How does patent expiration affect the future pricing of this drug?
Post-patent expiry, biosimilars or generics are likely to penetrate the market, significantly reducing the drug’s price—often by 30-50%—due to competition and payer cost containment strategies.

3. What are the main challenges facing pharmaceutical companies marketing this drug?
Key challenges include impending patent expiration, biosimilar competition, securing formulary access, demonstrating cost-effectiveness to payers, and addressing regulatory hurdles for expanding indications.

4. Are there upcoming regulatory changes likely to impact NDC 65649-0311’s market?
Potential regulatory developments such as expanded indications, new safety requirements, or accelerated approvals for novel formulations could broaden or restrict its market, influencing pricing and adoption.

5. How can manufacturers sustain profitability as biosimilars enter the market?
By innovating through new formulations or indications, securing comprehensive patent protections, engaging deeply with payers for favorable formulary status, and implementing patient support programs to enhance adherence.


Sources:
[1] IQVIA, "Pharmaceutical Market Trends," 2023.
[2] FDA Regulatory Updates, 2023.
[3] GlobalData, "Biopharmaceutical Market Outlook," 2023.
[4] Medicare Reimbursement Data, CMS, 2023.
[5] Industry Analyst Reports, 2023.

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