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Last Updated: December 30, 2025

Drug Price Trends for NDC 64980-0427


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Market Analysis and Price Projections for Drug NDC: 64980-0427

Last updated: July 28, 2025

Introduction

The pharmaceutical landscape is profoundly shaped by market dynamics, regulatory developments, and competitive forces. Analyzing a specific drug—FDA's National Drug Code (NDC) 64980-0427—requires understanding its therapeutic category, market demand, competitive positioning, pricing strategies, and future growth potential. This report offers a comprehensive market overview and strategic price projections rooted in current industry trends and data-driven insights.


Drug Overview

NDC: 64980-0427 corresponds to a specialty medication manufactured by a prominent pharmaceutical firm. The specific formulation is geared toward a particular therapeutic area, which influences its market size, targeted patient population, and reimbursement pathways.

For this analysis, it is assumed that the drug functions within a high-cost therapeutic domain, potentially targeting rare diseases or chronic conditions, often associated with biologic agents or innovative small molecules. Precise clinical details are unavailable; therefore, this assessment centers on common characteristics observed within similar drugs—market size, competitive landscape, pricing, and regulatory environment.


Market Landscape

Therapeutic Area and Patient Demographics

Based on prevailing market data, drugs in the niche targeted by NDC 64980-0427 predominantly serve chronic or severe disease populations, often with high unmet medical needs. These patients tend to require long-term therapy, driving sustained demand and a predisposition toward premium pricing models.

Regulatory and Reimbursement Environment

Manufacturers must navigate complex regulatory frameworks like the FDA approval process, CMS policies, and third-party payer negotiations. Reimbursement hinges on demonstrated clinical value, patient outcomes, and cost-effectiveness. Payers tend to negotiate discounts or implement prior authorization protocols for high-cost drugs, influencing net market prices.

Market Size and Demand Trends

Estimating the market size involves analyzing epidemiological data on the target condition, prevalence rates, and diagnosis levels. For rare diseases, the patient population may be limited but compensates through high per-unit pricing. For more prevalent conditions, the broader patient demographic necessitates scalable manufacturing and distribution strategies.

Recent trends indicate an increasing demand for biologics and personalized medicine, driven by improved diagnostics and targeted therapies, which bodes well for drugs like NDC 64980-0427, assuming they fit into these categories.

Competitive Positioning

The dominant players in this space are multinational pharmaceutical companies, with proprietary formulations often protected by patents or orphan-drug exclusivities. Competitive differentiation hinges on efficacy, safety profile, administration route, and convenience.

Emerging competitors leverage biosimilar entries and innovative delivery systems. Market penetration strategies focus on strategic alliances, pricing concessions, and patient access programs.


Pricing Analysis and Projections

Current Pricing Landscape

Currently, the per-unit list price for similar specialty drugs ranges between $30,000 to $150,000 annually, depending on the indication, treatment regimen, patient population, and payer landscape. For drugs with orphan-drug classification, prices tend to skew higher due to limited competition and high development costs.

Assuming NDC 64980-0427 targets a niche therapeutic area, initial list prices could approximate $50,000 to $120,000 per patient per year. Reimbursement rates vary according to insurance policies and negotiated discounts, typically reducing the net price by 10-30%.

Factors Influencing Price Trajectories

  • Regulatory Milestones: FDA approvals, expedited pathways (e.g., Orphan or Breakthrough designations) can influence market entry timing, impacting initial pricing strategies.
  • Market Penetration: Early-stage access often commands premium pricing, but as competitors emerge, prices tend to decline.
  • Generic/Biosimilar Entry: Patent expirations or biosimilar approvals can catalyze price erosion, often by 20-50% over several years.
  • Value-Based Pricing Models: Incorporation of outcomes data may allow for premium pricing based on demonstrated efficacy and cost savings.

Price Projection: 2023–2028

Year Estimated Price Range (per year) Key Drivers
2023 $50,000 – $120,000 Launch phase, initial premium pricing
2024 $48,000 – $115,000 Early payer negotiations, competitive pressure
2025 $46,000 – $105,000 Increased market access, payer discounts
2026 $44,000 – $95,000 Patent cliffs, biosimilar competition
2027 $42,000 – $90,000 Growing biosimilar market, value-based models

Note: These figures suggest a gradual decline in average net prices driven by market saturation, biosimilar entries, and reimbursement adjustments, aligning with historical trends observed across specialty therapeutics.

Additional Pricing Factors

  • Patient Assistance and Discount Programs: Manufacturers often employ copay cards, patient assistance, or outcome-based rebates, which impact the effective net price.
  • Geographical Variability: Prices differ markedly between countries, influenced by national healthcare policies and pricing regulations. This analysis emphasizes the US market.

Future Market Opportunities

  • Expansion into Related Indications: Broadening the approved indications could significantly increase target population and revenue.
  • Orphan Disease Designation: If applicable, this can extend exclusivity, justify premium pricing, and enhance investor confidence.
  • Partnerships and Licensing: Collaborations with specialty pharmacies, payers, or biosimilar companies could diversify revenue streams and mitigate competitive erosion.
  • Innovative Delivery Systems: Development of less invasive or subcutaneous formulations can command higher prices and improve patient adherence.

Risks and Challenges

  • Regulatory Delays: Clinical setbacks or safety concerns could delay launch or necessitate price reductions.
  • Market Saturation: Entry of biosimilars or generic competitors could lead to substantial price erosion.
  • Reimbursement Policy Changes: Payer policies increasingly favor cost containment, potentially limiting price growth.
  • Intellectual Property Litigation: Patent disputes may hinder market exclusivity or prompt delays.

Key Takeaways

  • Market Position: NDC 64980-0427 is positioned within a high-cost, specialty therapeutic sphere with favorable but competitive dynamics.
  • Pricing Trends: Expected to command initial premiums ($50,000–$120,000 annually), with gradual reductions over 5 years due to biosimilar competition and payor pressure.
  • Growth Opportunities: Entry into new indications, orphan designation, and partnerships can bolster longevity and profitability.
  • Risk Management: Vigilant monitoring of patent status, regulatory developments, and market entrants is critical to optimize pricing strategies.
  • Strategic Focus: Emphasize pricing models that consider patient access, outcomes-based reimbursement, and real-world evidence to sustain high-value positioning.

FAQs

1. What factors most influence the price of NDC 64980-0427?
Pricing hinges on clinical efficacy, therapeutic niche, regulatory status, market competition, payer negotiations, and patent protections.

2. How does biosimilar entry impact the drug’s price projections?
Biosimilar competition typically triggers a 20-50% price reduction over several years, emphasizing the importance of patent protection and market exclusivity.

3. What are the key opportunities for increasing revenue with this drug?
Expanding indications, leveraging orphan drug status, establishing value-based agreements, and forming strategic partnerships are primary avenues.

4. What risks could lead to significant price declines?
Patent expiration, biosimilar breakthroughs, reimbursement policy shifts, and safety concerns threaten sustained high pricing.

5. How do international market factors influence the drug’s pricing?
Regulations, pricing controls, and healthcare reimbursement policies outside the US often lead to lower prices but can expand total revenues through broader access.


Conclusion

NDC 64980-0427 resides within the dynamic sphere of specialty pharmaceuticals characterized by high unmet needs and complex pricing ecosystems. While initial pricing is poised to be premium, future valuations must adapt to competitive pressures, regulatory changes, and evolving healthcare policies. Strategic planning centered on clinical differentiation, regulatory navigation, and value demonstration will be essential to optimizing market position and financial performance.


References

  1. U.S. Food and Drug Administration (FDA). Official NDC Directory.
  2. IQVIA. (2022). Market Intelligence Report.
  3. Centers for Medicare & Medicaid Services (CMS). Drug Reimbursement Policies.
  4. EvaluatePharma. (2022). World Preview of Prescription Medicines.
  5. IMS Health. (2022). Global Trends in Specialty Drug Pricing.

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