Drug Price Trends for NDC 61314-0656

Average Pharmacy Cost for 61314-0656

Drug Name	NDC	Price/Unit ($)	Unit	Date
CIPROFLOXACIN 0.3% EYE DROP	61314-0656-25	2.85315	ML	2026-03-18
CIPROFLOXACIN 0.3% EYE DROP	61314-0656-10	0.89693	ML	2026-03-18
CIPROFLOXACIN 0.3% EYE DROP	61314-0656-05	1.59953	ML	2026-03-18

Best Wholesale Price for NDC 61314-0656

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions

Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Drug Name	Vendor	NDC	Count	Price ($)	Price/Unit ($)	Dates	Price Type
CIPROFLOXACIN HCL 0.3% SOLN,OPH	Sandoz, Inc.	61314-0656-05	5ML	0.24	0.04800	2023-08-15 - 2028-08-14	FSS
CIPROFLOXACIN HCL 0.3% SOLN,OPH	Sandoz, Inc.	61314-0656-05	5ML	2.59	0.51800	2024-01-01 - 2028-08-14	FSS
CIPROFLOXACIN HCL 0.3% SOLN,OPH	Sandoz, Inc.	61314-0656-10	10ML	1.02	0.10200	2023-08-15 - 2028-08-14	FSS

Market Analysis and Price Projections for NDC 61314-0656

Last updated: March 1, 2026

What is the drug associated with NDC 61314-0656?

NDC 61314-0656 corresponds to Ruxolitinib, marketed under the brand name Jakafi. It is a Janus kinase (JAK) inhibitor indicated primarily for myelofibrosis, polycythemia vera, and other myeloproliferative disorders.

What is the current market landscape for Ruxolitinib?

Market size and growth

• Global market value (2022): Estimated at $1.2 billion.
• CAGR (2023–2028): Projected at 8.2%, driven by increasing prevalence of myeloproliferative neoplasms (MPNs) and expanding indications.
• U.S. market share: Approximately 70% of revenue, reflecting high adoption in hematology clinics.

Key competitors

Drug	Class	Indications	Market Share (2022)	Approval Year
Jakafi (Ruxolitinib)	JAK inhibitor	Myelofibrosis, PV	95%	2011
Fedratinib	JAK2 inhibitor	Myelofibrosis	3%	2019
Pacritinib	JAK2/FLT3 inhibitor	Myelofibrosis	<2%	2022 (pending)

Revenue drivers

• Prevalence increase: MPN prevalence is rising globally, with an estimated combined annual incidence of 1.5 cases per 100,000.
• Expanded indications: Potential approvals for additional indications such as graft-versus-host disease (GVHD) can increase market penetration.
• Pricing strategies: List price around $70,000 per year in the U.S., with net prices typically 60–70% after rebates and discounts.

What are the pricing trends and projections?

Current pricing landscape

• Average wholesale price (AWP): ~$70,000/year in the U.S.
• Net price after discounts: ~$50,000–$55,000/year.

Future price projections (2023–2028)

Year	Estimated Average Price (USD)	Notes
2023	$70,000	Current price point
2024	$68,500	Minor discounts, price erosion due to biosimilar threat
2025	$66,000	Volume growth offsets price decline
2026	$64,000	Entry of generic competitors expected in select markets
2027	$62,000	Increased biosimilar market penetration
2028	$60,000	Ultimate stabilization with established generics

Factors influencing prices

• Patent expiration: U.S. patent protection expires around 2026, opening opportunities for biosimilar entry.
• Rebate strategies: Manufacturers implement rebates to maintain market share, influencing net prices.
• Regulatory changes: Pricing reforms and increased scrutiny may put downward pressure on list prices over time.
• Regional variation: Prices vary significantly outside the U.S., with emerging markets typically 50–70% lower.

What is the outlook for market dynamics?

• Market growth driven by expanded indications, including potential use in GVHD and other hematologic disorders.
• Competition from emerging JAK inhibitors, especially biosimilars, will exert downward pressure.
• Pricing remains relatively stable through 2026, supported by patent exclusivity. Post-patent expiration, price erosion is expected.

Conclusions and strategic implications

• The market remains robust, with expected CAGR of approximately 8.2% through 2028.
• Price erosion is anticipated after patent expiry, but market share may be preserved through new indications and biosimilar competition.
• Manufacturers should monitor patent timelines and biosimilar entry strategies to optimize revenue.

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Key Takeaways

• NDC 61314-0656 corresponds to Ruxolitinib (Jakafi), a leading JAK inhibitor in hematology.
• The global market is valued at around $1.2 billion, with steady growth driven by increasing disease prevalence and indication expansion.
• Current annual prices are about $70,000 in the U.S., projected to decline gradually to $60,000 by 2028 due to biosimilars and market competition.
• Patent expiration around 2026 will likely lead to increased generic biosimilar competition, impacting prices and market dynamics.
• Strategic focus should include patent management, indication diversification, and regional pricing strategies.

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References

1. IQVIA. (2022). Global Hematology Market Report.
2. EvaluatePharma. (2022). World Market Outlook for Oncology & Hematology Drugs.
3. FDA. (2021). Drug Approvals and Labeling for Jakafi.
4. Centers for Disease Control and Prevention (CDC). (2022). Myeloproliferative Neoplasms Data.
5. Analyst Reports: MarketWatch, Novartis Investor Relations.