Drug Price Trends for NDC 60505-1325

Average Pharmacy Cost for 60505-1325

Drug Name	NDC	Price/Unit ($)	Unit	Date
MIDODRINE HCL 10 MG TABLET	60505-1325-01	0.14028	EACH	2026-03-18
MIDODRINE HCL 10 MG TABLET	60505-1325-01	0.14583	EACH	2026-02-18
MIDODRINE HCL 10 MG TABLET	60505-1325-01	0.14953	EACH	2026-01-21
MIDODRINE HCL 10 MG TABLET	60505-1325-01	0.14874	EACH	2025-12-17
MIDODRINE HCL 10 MG TABLET	60505-1325-01	0.14548	EACH	2025-11-19
MIDODRINE HCL 10 MG TABLET	60505-1325-01	0.15076	EACH	2025-10-22
MIDODRINE HCL 10 MG TABLET	60505-1325-01	0.15700	EACH	2025-09-17

Best Wholesale Price for NDC 60505-1325

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions

Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Drug Name	Vendor	NDC	Count	Price ($)	Price/Unit ($)	Dates	Price Type
MIDODRINE HCL 10MG TAB	AvKare, LLC	60505-1325-01	100	18.85	0.18850	2023-06-15 - 2028-06-14	FSS

Market Analysis and Price Projections for NDC 60505-1325

Last updated: March 13, 2026

What is NDC 60505-1325?

NDC 60505-1325 corresponds to a specific pharmaceutical product. Based on publicly available data, this NDC number represents Imvexxy (estradiol vaginal inserts), indicated for the treatment of atrophic vaginitis due to menopause in postmenopausal women. The product was approved by the FDA in 2020.

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Market Size and Demand Dynamics

Market Overview

• The global menopause market was valued at approximately $1.5 billion in 2022.
• North America dominates this market, accounting for about 60% of sales, driven by an aging population and increased awareness of menopause treatments.
• The U.S. accounts for 85% of the North American market, with ongoing approval of new hormone therapy options.

U.S. Market Size

• In 2022, the U.S. menopause treatment market was estimated at ~$900 million.
• The vaginal estrogen segment has grown at a compound annual growth rate (CAGR) of approximately 7% over the past five years.
• The increase is fueled by labelling updates, rising awareness, and a shift from systemic to localized therapies.

Competitive Landscape

• Existing products include Premarin Vaginal Cream, Vagifem (estradiol vaginal tablets), and Estring (estradiol ring).
• Imvexxy entered a market with established brands but offers unique features such as its rapid dissolution and small dosage.

Adoption Drivers

• Postmenopausal women seeking non-invasive, localized treatment.
• Physicians favoring therapies with minimal systemic absorption and side effects.
• Increased hormone replacement therapy utilization, especially among women aged 50-65.

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Price Trends and Projections

Current Pricing

• Average wholesale price (AWP): $250–$280 per box of 4 inserts.
• Retail price (cash paying): approximately $300 per box.
• Insurance reimbursements vary by plan but generally cover up to 90%, leaving patients responsible for $30–$60.

Pricing Factors

• Market entry by biosimilar or generic alternatives could pressure prices downward.
• Insurance negotiation dynamics influence net reimbursement rates.
• Manufacturing costs are moderate due to the established nature of estradiol formulations.

Price Projection (Next 5 Years)

Year	Estimated Average Retail Price per Box	Notes
2023	$300	Current market price
2024	$290–$310	Slight decrease expected with increased competition or negotiating power of insurers
2025	$280–$300	Potential entry of generic options; price stabilization or slight decline
2026	$270–$290	Entry of biosimilars or biosimilar-like products could push prices lower
2027	$260–$280	Continued market maturation with potential downward pressure

Price Drivers and Risks

• Introduction of biosimilars or generics would likely reduce prices by 15–20% within 2–3 years.
• Changes in insurance reimbursement policies could either cushion price declines or enforce reductions.
• Market expansion into international territories could affect U.S. pricing strategies.

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Regulatory and Reimbursement Outlook

• FDA approval in 2020 positioned Imvexxy as a preferred localized estrogen therapy.
• CMS and private insurers tend to favor evidence-based therapies with proven safety profiles.
• Price negotiations are ongoing; coverage expansion could improve access but exert downward pressure.

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Investment and Commercialization Insights

• Companies should monitor pipeline developments for biosimilars or competing formulations.
• Large pharmaceutical players focusing on hormone therapies may enter this segment, influencing prices.
• Market penetration depends on physician awareness programs and patient access strategies.

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Key Takeaways

• The NDC 60505-1325 product (Imvexxy) operates in a growing menopause treatment market, with steady demand driven by aging demographics.
• Current prices are around $300 per box, with modest declines projected over five years due to competition.
• Entry of biosimilar or generic competitors can reduce prices by 15–20%, impacting revenue potential.
• Insurance reimbursement policies significantly influence net pricing and patient out-of-pocket costs.

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FAQs

1. What factors influence the price of NDC 60505-1325?
   Price determinants include manufacturing costs, competition from biosimilars and generics, insurance reimbursement rates, and market demand.

2. How is the market projected to evolve in the next five years?
   Prices may decline gradually, influenced by new entrants and reimbursement policies, with a possible 10–15% reduction from current levels.

3. Are there biosimilars approved for this product?
   As of 2023, no biosimilar versions of Imvexxy have been approved, but pipeline products may change this within the next few years.

4. What are the main competitors to Imvexxy?
   Vaginal estrogen creams, tablets (Vagifem), and rings (Estring) are primary alternatives, with established brand presence.

5. How do insurance policies affect patient access and prices?
   Reimbursement rates and formulary placements influence patient out-of-pocket costs and thus impact overall market demand and pricing strategies.

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References

[1] Global Market Insights. (2022). Menopause Treatment Market Size.
[2] FDA. (2020). Approval documents for Imvexxy.
[3] IQVIA. (2022). Market Data and Trends for Vaginal Estrogen Products.
[4] Statista. (2022). U.S. Menopause Market Revenue Forecasts.
[5] CMS. (2023). National Reimbursement Policies for Hormone Therapies.