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Last Updated: July 18, 2025

Drug Price Trends for MIDODRINE HCL


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Drug Price Trends for MIDODRINE HCL

Average Pharmacy Cost for MIDODRINE HCL

These are average pharmacy acquisition costs (net of discounts) from a US national survey
Drug Name NDC Price/Unit ($) Unit Date
MIDODRINE HCL 10 MG TABLET 00378-1903-01 0.19753 EACH 2025-06-18
MIDODRINE HCL 10 MG TABLET 00904-6819-07 0.19753 EACH 2025-06-18
MIDODRINE HCL 10 MG TABLET 50268-0563-15 0.19753 EACH 2025-06-18
MIDODRINE HCL 10 MG TABLET 00245-0213-11 0.19753 EACH 2025-06-18
MIDODRINE HCL 10 MG TABLET 49884-0874-01 0.19753 EACH 2025-06-18
MIDODRINE HCL 5 MG TABLET 82293-0004-10 0.15034 EACH 2025-06-18
>Drug Name >NDC >Price/Unit ($) >Unit >Date

Best Wholesale Price for MIDODRINE HCL

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available to any customer under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Unit Dates Price Type
MIDODRINE HCL 2.5MG TAB Golden State Medical Supply, Inc. 51407-0388-90 90 5.83 0.06478 EACH 2023-06-15 - 2028-06-14 FSS
MIDODRINE HCL 5MG TAB Golden State Medical Supply, Inc. 51407-0389-90 90 8.52 0.09467 EACH 2023-06-15 - 2028-06-14 FSS
MIDODRINE HCL 10MG TAB Golden State Medical Supply, Inc. 51407-0390-90 90 16.49 0.18322 EACH 2023-06-15 - 2028-06-14 FSS
MIDODRINE HCL 2.5MG TAB AvKare, LLC 60505-1320-01 100 7.30 0.07300 EACH 2023-06-15 - 2028-06-14 FSS
MIDODRINE HCL 2.5MG TAB AvKare, LLC 42291-0560-90 90 8.33 0.09256 EACH 2023-06-15 - 2028-06-14 FSS
MIDODRINE HCL 5MG TAB AvKare, LLC 60505-1321-01 100 9.91 0.09910 EACH 2023-06-15 - 2028-06-14 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Unit >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for Midodrine Hydrochloride

Last updated: January 1, 2025

Introduction

Midodrine hydrochloride, a synthetic sympathomimetic amine, is primarily used to treat orthostatic hypotension and other related conditions. This article delves into the market dynamics, financial trajectory, and price projections of midodrine hydrochloride, highlighting key drivers, market segmentation, challenges, and opportunities.

Market Size and Growth Projections

The midodrine hydrochloride market has been valued at USD 744.93 million in 2023 and is projected to grow significantly, reaching USD 1,313.81 million by 2031. This growth is anticipated at a Compound Annual Growth Rate (CAGR) of 5.36% from 2024 to 2031[1][3].

Key Drivers of Market Growth

Several factors are driving the growth of the midodrine hydrochloride market:

Rising Incidence of Orthostatic Hypotension

The increasing prevalence of orthostatic hypotension, particularly among the elderly population, is a major driver. As the global population ages, the demand for treatments like midodrine hydrochloride is expected to rise[1][3].

Increased Awareness and Diagnosis

Growing awareness and improved diagnostic techniques for orthostatic hypotension are leading to more patients being identified and treated, thereby increasing the demand for midodrine hydrochloride[1][3].

Healthcare Infrastructure and Reimbursement

Improvements in healthcare infrastructure and favorable reimbursement policies are also contributing to the market's expansion. Governments and health insurance providers are increasingly supporting the use of midodrine hydrochloride, making it more accessible to patients[1][3].

Market Segmentation

The midodrine hydrochloride market is segmented based on several key factors:

Application

Midodrine hydrochloride is used in treating various conditions, including anaphylaxis, cardiac arrest, and primarily orthostatic hypotension. The therapeutic area of orthostatic hypotension is the most significant segment driving the market[1][3].

Product Form

The drug is available in oral tablets and oral solution forms. The oral tablet form is the most commonly used and preferred by patients due to its ease of administration[1][3].

Geographical Regions

The market is geographically segmented into North America, Europe, Asia-Pacific, South America, and the Middle-East and Africa. The Asia-Pacific region, particularly China, is showing significant growth due to rapid advancements in the pharmaceutical industry and increasing healthcare needs[1][3].

Price Analysis

The cost of midodrine hydrochloride can vary based on several factors, including dosage, pharmacy, and insurance coverage.

Dosage and Pricing

Midodrine hydrochloride is available in 2.5 mg, 5 mg, and 10 mg oral tablets. Here are some approximate price ranges for a 30-day supply:

  • 2.5 mg: From $13.80 to $18.11 for 30 tablets[2].
  • 5 mg: From $16.67 to $23.85 for 30 tablets[2].
  • 10 mg: From $19.96 to $30.44 for 30 tablets[2].

Cost Savings

Patients can save on midodrine costs by using coupons, discount cards, and opting for a 90-day supply if approved by their insurance company. For example, using an Optum Perks coupon can save up to $207 per fill off the retail price[5].

Challenges

Regulatory Hurdles

The need for additional clinical trials to verify clinical efficacy has posed challenges. However, these trials also provide opportunities to strengthen the drug's market position[1].

Supine Hypertension

Midodrine hydrochloride can cause supine hypertension, a significant side effect that requires careful management. This has led to the exploration of combination therapies to mitigate this risk[1].

Opportunities

Expanding Therapeutic Uses

Ongoing research aimed at broadening the therapeutic applications of midodrine hydrochloride presents significant opportunities for market growth. This includes exploring its use in other cardiovascular conditions[1][3].

Emerging Markets

The growing healthcare needs in emerging markets, particularly in the Asia-Pacific region, offer new avenues for expansion. Rapid advancements in the pharmaceutical industry and increasing healthcare infrastructure in these regions are driving this growth[1][3].

Market Trends and Projections

The midodrine hydrochloride market is expected to grow rapidly due to several key trends:

Aging Population

The global population is aging, leading to an increased incidence of orthostatic hypotension and other age-related conditions. This demographic shift is a significant driver of the market[1][3].

Technological Advancements

Improvements in diagnostic techniques and healthcare infrastructure are enhancing the detection and treatment of orthostatic hypotension, further driving the demand for midodrine hydrochloride[1][3].

Research and Development

Continuous research and development efforts to broaden the therapeutic uses of midodrine hydrochloride and to mitigate side effects such as supine hypertension are crucial for market expansion[1][3].

Key Takeaways

  • The midodrine hydrochloride market is expected to grow significantly, driven by the rising incidence of orthostatic hypotension and favorable healthcare policies.
  • The market is segmented by application, product form, and geographical regions, with the Asia-Pacific region showing rapid growth.
  • Generic manufacturers play a crucial role in the market, and regulatory compliance is essential for maintaining market authorization.
  • Continuous research and development efforts are key to expanding the drug's therapeutic uses and market share.

FAQs

What is the current market size of midodrine hydrochloride?

The midodrine hydrochloride market was valued at USD 744.93 million in 2023[1][3].

How is the midodrine hydrochloride market expected to grow?

The market is expected to grow at a CAGR of 5.36% from 2024 to 2031, reaching USD 1,313.81 million by 2031[1][3].

What are the key drivers of the midodrine hydrochloride market?

The key drivers include the rising incidence of orthostatic hypotension, increased awareness and diagnosis, improvements in healthcare infrastructure, and favorable reimbursement policies[1][3].

How can patients save on midodrine hydrochloride costs?

Patients can save by using coupons, discount cards, and opting for a 90-day supply if approved by their insurance company[5].

What are the potential side effects of midodrine hydrochloride?

One significant side effect is supine hypertension, which requires careful management and may lead to the exploration of combination therapies[1].

Sources

  1. DrugPatentWatch: Midodrine hydrochloride - Generic Drug Details[1].
  2. Drugs.com: Midodrine Prices, Coupons, Copay Cards & Patient Assistance[2].
  3. MarketResearchIntellect: Midodrine Market Size, Trends and Projections[3].
  4. Maiaresearch: Global Midodrine Hydrochloride Industry Market Research Report[4].
  5. Healthline: Midodrine and Cost: How to Find Savings and More[5].

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