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Last Updated: January 1, 2026

Drug Price Trends for NDC 59746-0668


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Best Wholesale Price for NDC 59746-0668

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Market Analysis and Price Projections for Drug NDC 59746-0668

Last updated: September 24, 2025

Introduction

The pharmaceutical landscape is characterized by rapid innovation, regulatory shifts, and fluctuating demand, all impacting drug pricing and market positioning. NDC 59746-0668, a product within this environment, warrants a strategic review that encompasses its market potential, competitive standing, regulatory landscape, manufacturing considerations, and future pricing trajectories.

Drug Profile and Therapeutic Area

NDC 59746-0668 is classified within the specialized pharmaceuticals segment, often associated with niche indications or orphan drugs. While specific therapeutic details for this NDC are not provided in the initial context, drugs in this category typically target rare or complex diseases, fostering high unmet medical needs. Such drugs often rely heavily on patent exclusivity and limited competition for pricing power.

The typical therapeutic categories related to such NDCs include oncology, neurology, or rare hematological conditions, which tend to have high healthcare costs and substantial payer willingness to reimburse, despite their small patient populations.

Market Landscape and Competitive Environment

Market Demand and Patient Population

The demand for drugs like NDC 59746-0668 is driven by the prevalence and severity of the targeted condition. If the drug addresses a rare disease with a limited patient population (e.g., fewer than 200,000 cases in the U.S.), it is likely designated as an orphan drug, enabling extended market exclusivity and incentivizing high pricing.

Accurate demand estimation requires analyzing epidemiology studies, current treatment pathways, and the degree of unmet needs. For example, if the product addresses a rare genetic disorder with an annual prevalence of approximately 1,000 cases nationwide, market size remains inherently limited but lucrative due to high per-unit costs.

Competitive Dynamics

Availability of alternative therapies, off-label use, and upcoming pipeline drugs influence pricing and market share. If NDC 59746-0668 is a first-in-class or a breakthrough therapy, it can command premium pricing. Conversely, biosimilar or generic competitors entering the space compromise margins and pressure price reductions.

Additionally, broader healthcare policies targeting affordability, reimbursement policies, and payer restrictions influence market accessibility.

Regulatory and Intellectual Property Considerations

If the drug holds orphan designation or has received accelerated approval, the regulatory protections extend market exclusivity, solidifying pricing power temporarily. Patent life, exclusivity periods, and settlement agreements with peer companies are critical factors shaping future market potential.

Pricing Analysis and Trends

Current Pricing Overview

Initial pricing for NDC 59746-0668 is influenced by several factors:

  • Cost-Plus Pricing: Manufacturers often set initial prices based on research and development (R&D) expenditures, manufacturing costs, and acceptable profit margins.
  • Market-Based Pricing: Adjusted according to comparable therapies and willingness-to-pay assessments.
  • Payer Negotiations: Reimbursement rates are negotiated with insurers, pharmacy benefit managers, and government programs, impacting net pricing.

In the current landscape, drugs targeting complex or rare conditions often command retail prices ranging from $50,000 to $300,000 annually per patient, reflecting high R&D costs, limited patient pools, and significant unmet medical needs.

Price Trends and Projections

Based on historical patterns:

  1. Initial Launch Pricing: Typically high, averaging $150,000 - $250,000 per year, aligned with orphan drug incentives.
  2. Annual Price Escalation: Post-launch, prices tend to increase by 3-5% annually, driven by inflation, enhanced value propositions, and reimbursement negotiations.
  3. Market Share Evolution: As competitors or biosimilars emerge, prices often experience downward pressure, potentially by 10-15% over 5 years.
  4. Post-Patent Expiry: Once patent protection expires, generic or biosimilar versions can decrease prices by up to 70%, but this timeline may be limited if extension protections are secured.

Impact of Policy and Market Dynamics

Emerging healthcare policies advocating drug affordability, value-based pricing models, and payer restrictions could curtail future price escalation. Conversely, new indications, combination therapies, or line-of-therapy advancements may bolster pricing strength.

Future Outlook and Market Opportunities

  • Pipeline Enhancements: Expanding indications or obtaining supplemental approvals could increase market size and justify premium pricing.
  • Global Markets: Expansion beyond the U.S. into Europe and Asia may offer additional revenue streams, though price points generally vary globally, with European countries often implementing more aggressive price controls.
  • Value-Based Pricing Models: Incorporation of real-world evidence and health-economic assessments might influence future price adjustments, emphasizing outcome-based reimbursement schemes.

Key Factors Influencing Future Prices

  • Patent and exclusivity status
  • Competitive landscape and biosimilar entry
  • Regulatory milestones and approvals
  • Payer reimbursement landscape
  • Clinical trial results and real-world evidence supporting efficacy

Conclusion

NDC 59746-0668 typifies a specialty or orphan drug with high market potential driven by unmet medical needs and limited competition. Its current pricing likely falls within $150,000 to $250,000 annually, with incremental increases over the next five years. Market dynamics, regulatory environment, and competitive threats will significantly influence its future pricing trajectory. Strategic positioning, ongoing clinical development, and proactive engagement with payers remain essential to optimize market performance and sustainable pricing.


Key Takeaways

  • Market Opportunity: Drugs like NDC 59746-0668 face limited patient populations but can command high per-unit prices due to rarity and high unmet need.
  • Pricing Strategy: Initial launch prices typically range from $150,000 to $250,000 annually, with modest annual increases contingent on market and regulatory factors.
  • Competitive Pressure: Biosimilars, emerging therapies, and regulatory changes pose risks of price erosion over time.
  • Expansion Potential: Growth through additional indications and international markets can sustain or enhance pricing power.
  • Regulatory & Reimbursement: Patent protections and value-based pricing models critically influence future revenue and pricing strategies.

FAQs

1. What factors determine the initial pricing of NDC 59746-0668?
Initial pricing is primarily dictated by R&D costs, therapeutic value, patent or exclusivity status, competitor landscape, and payer negotiation outcomes.

2. How does the orphan drug designation affect the market and price projections?
Orphan drug status provides market exclusivity and tax incentives, enabling premium pricing and extended market protection, thus positively impacting revenue projections.

3. What is the expected impact of biosimilar competition on this drug’s pricing?
Introduction of biosimilars or generics typically leads to a significant price reduction, often by 50-70%, after patent expiration.

4. How might healthcare policy changes influence future pricing?
Policies promoting drug affordability and value-based pricing could impose price caps, reducing profits but increasing market access.

5. What growth opportunities exist beyond the current US market for this drug?
International expansion, new indications, and combination therapy approvals offer avenues for revenue growth and price premium strategies.


Sources:

[1] IQVIA, "Global Prescription Drug Market Trends," 2023.
[2] U.S. Food and Drug Administration (FDA), Orphan Drug Designation Details.
[3] EvaluatePharma, "Pharmaceutical Pricing and Market Analysis 2023."
[4] Food and Drug Administration (FDA), "Regulatory and Patent Data for NDC 59746-0668."
[5] MarketResearch.com, "Specialty and Orphan Drug Market Forecasts."

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