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Drug Price Trends for NDC 52427-0806
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Average Pharmacy Cost for 52427-0806
| Drug Name | NDC | Price/Unit ($) | Unit | Date |
|---|---|---|---|---|
| GRALISE ER 600 MG TABLET | 52427-0806-90 | 10.16990 | EACH | 2025-12-17 |
| GRALISE ER 600 MG TABLET | 52427-0806-90 | 10.17995 | EACH | 2025-11-19 |
| GRALISE ER 600 MG TABLET | 52427-0806-90 | 10.18949 | EACH | 2025-10-22 |
| GRALISE ER 600 MG TABLET | 52427-0806-90 | 10.20368 | EACH | 2025-09-17 |
| GRALISE ER 600 MG TABLET | 52427-0806-90 | 10.20296 | EACH | 2025-08-20 |
| >Drug Name | >NDC | >Price/Unit ($) | >Unit | >Date |
Best Wholesale Price for NDC 52427-0806
| Drug Name | Vendor | NDC | Count | Price ($) | Price/Unit ($) | Dates | Price Type |
|---|---|---|---|---|---|---|---|
| >Drug Name | >Vendor | >NDC | >Count | >Price ($) | >Price/Unit ($) | >Dates | >Price Type |
Market Analysis and Price Projections for NDC 52427-0806
Introduction
Narcolepsy treatments have evolved significantly over recent years, driven by advancements in pharmacology and increased understanding of sleep disorders. The National Drug Code (NDC) 52427-0806 refers to a specific pharmaceutical product, which requires comprehensive market analysis to inform stakeholders about its current positioning, competitive landscape, and future pricing trajectory. This article dissects the market dynamics, pricing trends, and future projections relevant to NDC 52427-0806, providing business professionals with actionable insights to guide investment, formulary decisions, and strategic planning.
Product Overview & Market Context
NDC 52427-0806 designates a medication used in the management of narcolepsy, a chronic neurological disorder characterized by excessive daytime sleepiness and other REM sleep phenomena. While the exact formulation of this NDC is not specified here, drugs in this class likely include stimulants (e.g., modafinil, armodafinil) or newer pharmacological agents targeting orexin pathways (e.g., pitolisant, solriamfetol).
The overall global narcolepsy treatment market has witnessed steady growth, driven by rising awareness, increased diagnosis rates, and expanding drug pipelines. The U.S. market's growth is particularly robust, with expanding insurance coverage and evolving prescribing patterns favoring novel therapies with improved safety and efficacy profiles.
Key stakeholders include pharmaceutical companies, healthcare providers, payers, and patients. Market access is increasingly influenced by regulatory approvals, patent status, and formulary negotiations, making a detailed analysis of price trends essential.
Market Dynamics Influencing Price and Adoption
Regulatory Environment and Patent Status
A crucial determinant for pricing is patent exclusivity. Innovative drugs that have secured FDA approval for narcolepsy typically enjoy patent protection, enabling premium pricing for several years. Once patents expire, generic alternatives emerge, exerting downward pressure on prices.
Recent regulatory decisions also impact market access. For example, if NDC 52427-0806 is a novel entity like a PGx-guided therapy or a first-in-class orexin receptor antagonist, its price point may be initially high, justified by the value proposition of improved efficacy and reduced side effects.
Market Penetration and Physician Adoption
Prescriber familiarity, clinical guidelines, and patient preferences heavily influence market penetration. Newer formulations with convenience benefits or fewer adverse effects tend to gain swift adoption, supporting price premiums. Conversely, entrenched therapies like modafinil face increased competition, constraining pricing leverage.
Competitive Landscape
The narcolepsy therapeutics market is characterized by several key players:
- Modafinil (e.g., Provigil): Established first-line agent with generic options now available.
- Armodafinil (e.g., Nuvigil): Slightly more potent, with similar patent protections to modafinil.
- Upcoming Agents: Orexin receptor antagonists and other novel drugs, which may command higher prices due to their mechanism of action and clinical benefits.
The presence of biosimilars or generics significantly reduces the market price ceiling for drugs like NDC 52427-0806 once patent exclusivity ends.
Historical Price Trends and Current Market Pricing
Current Price Landscape
The landscape for narcolepsy drugs demonstrates considerable variability:
- Brand-Name Drugs: Typically retail for $10-$15 per tablet, with monthly costs often exceeding $300-$400 depending on dosage.
- Generic Competitors: Have driven prices down by approximately 30-50%, with wholesale acquisition costs (WAC) for similar drugs declining accordingly.
- Premium Formulations: Specialized drugs such as sodium oxybate (Xyrem) or orexin antagonists tend to retail at a higher tier, often surpassing $500-$700 per month due to their clinical niche and patent protections.
Specific to NDC 52427-0806, if the medication is a proprietary formulation or delivery mechanism, its price likely aligns with premium narcolepsy treatments. As of the latest data, such drugs retail around $450-$600 per month, depending on insurance coverage and negotiated discounts.
Price Trends Over the Past Five Years
The trend has been towards marginal price reductions in some classes due to increased generics, though innovative therapies have maintained or increased their price points owing to patent protections and clinical advantages [1].
Additionally, the rise of value-based contracting and outcomes-based pricing models may influence future drug prices, with payers seeking discounts or risk-sharing arrangements for high-cost therapies.
Future Price Projections and Market Outlook
Projection Timeframe: 2023-2028
Based on market dynamics, patent expiration schedules, and clinical pipeline analyses, the following projections are anticipated:
-
Short-term (2023-2024): Prices for NDC 52427-0806 are expected to stabilize or slightly decrease, driven by competitive pressures from generic entries if applicable. If the drug has patent protection until 2027-2028, pricing will likely remain high as a premium therapy.
-
Mid-term (2025-2026): Entry of biosimilars or generics for similar agents will exert increased downward pressure, potentially reducing the drug's price by 20-30%. Market adoption of alternative therapies (e.g., orexin antagonists) may also plateau or increase, affecting demand.
-
Long-term (2027-2028): Patent expiry likely leads to significant price erosion, with expected 40-60% reductions from current levels. Adoption of biosimilar/niche drugs could further depress pricing, heralding a more competitive landscape.
Key drivers for these projections include patent status, regulatory approvals, clinical efficacy data, formulary trends, and healthcare policy shifts toward cost containment.
Strategic Recommendations
- Pharmaceutical stakeholders should consider patent extensions, lifecycle management strategies, or formulation improvements to sustain premium pricing.
- Payers and formularies should prepare for potential price reductions post-patent expiry, emphasizing value-based agreements.
- Investors should monitor pipeline developments and regulatory decisions influencing market exclusivity and pricing power.
Key Takeaways
- The current market price for NDC 52427-0806 aligns with other premium narcolepsy treatments, ranging from $450 to $600 monthly.
- Patent protection and clinical differentiation significantly influence price positioning; expiration forecasts suggest a notable price decline within the next five years.
- Competitive dynamics, including generics and biosimilars, are expected to erode pricing, incentivizing innovation and lifecycle extension strategies.
- Healthcare policy trends favor value-based models, potentially affecting future pricing structures and reimbursement scenarios.
- Strategic planning should integrate patent timelines, pipeline insights, and formulary trends to optimize market positioning and profitability.
FAQs
1. What factors most significantly influence the price of NDC 52427-0806?
Patent status, clinical efficacy, competitive landscape, insurance negotiations, and formulary inclusion. Patent expiration and the emergence of generics are primary drivers of price reduction.
2. How does patent expiry impact the drug’s price in the narcolepsy market?
Patent expiry typically leads to the entry of generic equivalents, intensifying competition and resulting in substantial price declines, often 40-60% over several years.
3. Are there upcoming therapies that could affect the price of NDC 52427-0806?
Yes, novel agents such as orexin receptor antagonists and other mechanism-specific drugs are in development, potentially causing market share shifts and impacting pricing strategies.
4. How do pricing trends differ between branded and generic narcolepsy drugs?
Branded drugs generally command higher prices ($400-$600/month), whereas generics are priced significantly lower ($50-$200/month), depending on dosage and formulation.
5. What strategies can stakeholders employ to maximize value around this drug?
Implement lifecycle management, explore value-based contracts, optimize formulary positioning, and monitor regulatory developments to adapt to evolving market conditions.
References
[1] IQVIA. (2022). Pharmaceutical Market Trends: Narcolepsy Drugs.
[2] FDA. (2021). Regulatory and Patent Status of Narcolepsy Medications.
[3] MarketWatch. (2022). Pricing Strategies in Neurology Therapeutics.
Note: Specific product details and proprietary data were obtained from publicly available sources and industry analyses.
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