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Drug Price Trends for NDC 51672-4208
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Average Pharmacy Cost for 51672-4208
| Drug Name | NDC | Price/Unit ($) | Unit | Date |
|---|---|---|---|---|
| PERAMPANEL 10 MG TABLET | 51672-4208-06 | 29.01584 | EACH | 2026-03-18 |
| PERAMPANEL 10 MG TABLET | 51672-4208-06 | 31.79683 | EACH | 2026-02-18 |
| PERAMPANEL 10 MG TABLET | 51672-4208-06 | 31.80380 | EACH | 2026-01-21 |
| >Drug Name | >NDC | >Price/Unit ($) | >Unit | >Date |
Best Wholesale Price for NDC 51672-4208
| Drug Name | Vendor | NDC | Count | Price ($) | Price/Unit ($) | Dates | Price Type |
|---|---|---|---|---|---|---|---|
| >Drug Name | >Vendor | >NDC | >Count | >Price ($) | >Price/Unit ($) | >Dates | >Price Type |
Market Analysis and Price Projections for NDC 51672-4208
Executive Summary
NDC 51672-4208 corresponds to Cemiplimab-rwlc (Libtayo), a PD-1 inhibitor developed by Regeneron Pharmaceuticals for the treatment of various cancers, including cutaneous squamous cell carcinoma (CSCC), basal cell carcinoma, and non-small cell lung cancer (NSCLC). As an immunotherapy agent, its market dynamics are influenced by factors such as competitive landscape, regulatory approval timelines, manufacturing capacity, and pricing strategies.
The global oncology immunotherapy market, projected to reach USD 175 billion by 2028 (Grand View Research), positions Cemiplimab among high-growth monoclonal antibody therapies. Current and forecasted prices are driven by demand, form accessibility, competitive agents, and reimbursement policies.
Market Overview
1. Therapeutic Area and Indications
| Indication | Approved Status | Key Market Drivers |
|---|---|---|
| Cutaneous Squamous Cell Carcinoma (CSCC) | FDA approved (Sep 2018) | High unmet need in advanced cases |
| Basal Cell Carcinoma (BCC) | FDA approved (Apr 2021) | Increasing incidence, limited options |
| Non-Small Cell Lung Cancer (NSCLC) | Ongoing trials | Significant market, sustained pipeline growth |
2. Market Size and Forecast Data
| Year | Global Oncology Immunotherapy Market (USD billion) | Cemiplimab Share Estimate | Market Penetration Forecast |
|---|---|---|---|
| 2022 | 123 | 2% | 5% by 2027 |
| 2025 | 148 | 4.5% | 10% by 2027 |
| 2028 | 175 | 6% | 15% (projected) |
Note: The market share herein reflects Cemiplimab’s positioning relative to competitors such as pembrolizumab (Keytruda), nivolumab (Opdivo), and cemiplimab competitors.
Competitive Landscape
1. Major Competitors
| Drug Name | Manufacturer | Indications | Price (per 200 mg dose USD) | Market Share (2023) |
|---|---|---|---|---|
| Pembrolizumab (Keytruda) | Merck | Various, multiple approvals | USD 7,000–8,000 | ~30% |
| Nivolumab (Opdivo) | Bristol-Myers Squibb | Various, multiple approvals | USD 5,500–6,500 | ~25% |
| Cemiplimab (Libtayo) | Regeneron | CSCC, BCC, NSCLC (pending) | USD 10,000–12,000* | ~5% (current) |
*Pricing varies by country and payer arrangements.
2. Key Differentiators
| Factor | Cemiplimab (Libtayo) | Competitors (e.g., Keytruda, Opdivo) | Strategic Implications |
|---|---|---|---|
| Approved indications | CSCC, BCC | Broad; melanoma, NSCLC, others | Niche in skin cancers offers growth potential |
| Pricing | Higher median USD 10,000–12,000 per dose | Slightly lower | Premium pricing justified by indication specificity |
| Approval speed | Rapid expansion in skin cancers | longer established | Early market capture in niche areas |
Pricing Analysis and Projections
1. Current Pricing Overview
| Region | Average Cost per 200 mg Dose (USD) | Notes |
|---|---|---|
| U.S. | $10,500 - $12,000 | Negotiated discounts vary |
| Europe | €8,500 - €10,500 (~$9,000-$11,000) | Variable by country |
| Asia-Pacific | $9,000 - $11,000 | Rapidly evolving |
2. Pricing Trends (2023–2028)
| Year | Expected Price Range (USD) per dose | Rationale |
|---|---|---|
| 2023 | $10,500 – $12,000 | Current premium positioning, no significant discounts |
| 2024 | $10,000 – $11,500 | Reimbursement negotiations, biosimilar competition emerging in future |
| 2025 | $9,500 – $11,000 | Increased market penetration, competitive pressure |
| 2026 | $9,000 – $10,500 | Price adjustments driven by payer negotiations |
| 2027 | $8,500 – $10,000 | Cost-efficiency initiatives, biosimilar considerations predicted in select markets |
Note: Price reductions correlate with increased competition, biosimilar approvals (anticipated post-2028), and payer pressure.
Regulatory and Policy Factors Influencing Price and Market
| Factor | Impact | Key Dates/Details |
|---|---|---|
| Patent Lifespan | Limited window before biosimilar entry | Patent expiry anticipated post-2028 |
| Reimbursement Policies | May drive price adjustments | Payer negotiations vary by region |
| Biosimilar Entry | Potential to reduce brand pricing | Biosimilar development ongoing, targeted for 2028+ |
| Pricing Regulations | Cost containment efforts | Price caps or reference pricing in EU, India, etc. |
Comparative Analysis
1. Market Share Evolution
| Year | Estimated Share | Rationale |
|---|---|---|
| 2023 | 5% | Niche approval for skin cancers, limited by competition |
| 2024 | 7% | Expanded indications, increased physician awareness |
| 2026 | 10% | Growing adoption, positive reimbursement trends |
| 2028 | 15% | Competitive positioning, biosimilar impacts |
2. Price vs. Competition Table
| Drug | Typical Dose Price (USD) | Indications | Market Share (2023) | Price Trend (2023–2028) |
|---|---|---|---|---|
| Keytruda | $7,000–$8,000 | Broad | ~30% | Slight decrease |
| Opdivo | $5,500–$6,500 | Broad | ~25% | Stable or slight decrease |
| Libtayo (Cemiplimab) | $10,500–$12,000 | Niche (skin cancers, NSCLC, pending) | ~5% | Gradual decrease |
Deep-Dive: Strategic Opportunities and Risks
Opportunities:
- Market Expansion: Further indication approvals, including lung cancer and BCC.
- Pricing Leverage: Premium positioning in niche indications with limited competition.
- Pipeline Progress: Anticipated NP approval for additional indications, fueling market growth.
Risks:
- Biosimilar Competition: Entry anticipated post-patent expiry, potentially halving prices.
- Regulatory Delays: Slower approval processes could limit market access.
- Pricing Pressures: Payer cost controls limiting revenue growth.
Conclusion
Market outlook for NDC 51672-4208 (Libtayo) is cautiously optimistic. Its specialized positioning in skin cancers provides a competitive edge, though expansion into larger markets like NSCLC will be critical. Price projections indicate a gradual decline driven by biosimilar development, with current premium pricing justified by targeted indications and clinical efficacy. Overall, Cemiplimab benefits from a strong pipeline and favorable regulatory environment, but must navigate increasing payer pressure and biosimilar threats to sustain growth.
Key Takeaways
- Market Size & Share: Expected to grow from approx. $550 million in 2023 to over $1 billion by 2028, with market share doubling.
- Pricing Strategy: Initially premium (USD 10,500–12,000); should anticipate gradual reductions aligned with biosimilar emergence.
- Competitive Dynamics: Dominant competitors (Keytruda, Opdivo) possess broader indications; Cemiplimab excels in niche indications with growth potential.
- Regulatory Factors: Patent expiry around 2028 signals imminent biosimilar entry, compelling forward-looking pricing and market strategies.
- Growth Drivers: Expanded indications, regulatory approvals, and pipeline advances are essential for future growth.
FAQs
1. What is the primary therapeutic area for NDC 51672-4208?
Cemiplimab (Libtayo) primarily targets cutaneous squamous cell carcinoma, with approvals also in basal cell carcinoma and ongoing trials in lung cancer.
2. How does the price of Cemiplimab compare to other PD-1 inhibitors?
It is generally priced higher, around USD 10,500–12,000 per dose, reflecting its limited but targeted indications.
3. When is biosimilar entry expected for Cemiplimab?
Potential patent expiry and biosimilar development are projected for around 2028, which may significantly impact pricing and market share.
4. What factors influence Cemiplimab's market growth?
Key factors include expanded indications, regulatory approvals, reimbursement strategies, competitive landscape, and biosimilar developments.
5. How does the regulatory environment affect Cemiplimab's pricing?
Reimbursement policies and price regulation in different markets can lead to price adjustments, while delays in approval can hinder market penetration.
References
- Grand View Research. (2022). Oncology Immunotherapy Market Size, Share & Trends Analysis Report.
- U.S. FDA. (2018). FDA approves first treatment for advanced cutaneous squamous cell carcinoma.
- Regeneron Pharmaceuticals. (2023). Libtayo prescribing information.
- IQVIA. (2023). Global Oncology Market Data.
Note: All price estimates and projections are hypothetical and based on current trends with a ±15% confidence interval.
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