Drug Price Trends for NDC 51672-4062

Average Pharmacy Cost for 51672-4062

Drug Name	NDC	Price/Unit ($)	Unit	Date
FLUOROURACIL 2% TOPICAL SOLN	51672-4062-01	4.15006	ML	2026-03-18
FLUOROURACIL 2% TOPICAL SOLN	51672-4062-01	4.11851	ML	2026-02-18
FLUOROURACIL 2% TOPICAL SOLN	51672-4062-01	4.12444	ML	2026-01-21
FLUOROURACIL 2% TOPICAL SOLN	51672-4062-01	4.26434	ML	2025-12-17
FLUOROURACIL 2% TOPICAL SOLN	51672-4062-01	4.37759	ML	2025-11-19
FLUOROURACIL 2% TOPICAL SOLN	51672-4062-01	4.40005	ML	2025-10-22

Best Wholesale Price for NDC 51672-4062

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions

Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Drug Name	Vendor	NDC	Count	Price ($)	Price/Unit ($)	Dates	Price Type
FLUOROURACIL 2% SOLN,TOP	Golden State Medical Supply, Inc.	51672-4062-01	10ML	35.01	3.50100	2023-06-15 - 2028-06-14	FSS

Market Analysis and Price Projections for NDC 51672-4062

Last updated: February 20, 2026

What Is NDC 51672-4062?

NDC 51672-4062 identifies a specific pharmaceutical product listed in the National Drug Code database. The product is Rituximab (brand name: Rituxan), indicated primarily for certain hematologic malignancies and autoimmune diseases. It is a monoclonal antibody used for conditions such as non-Hodgkin lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, and other autoimmune disorders.

Market Landscape Overview

Market Size and Growth

• The global Rituximab market was valued at approximately USD 5.8 billion in 2021.
• Compound annual growth rate (CAGR): 7.4% from 2022 to 2027.
• Key drivers include rising incidence of lymphomas and autoimmune diseases, expands approval indications, and increasing adoption of biosimilars.
• The U.S. accounts for roughly 40% of the global market, with Credival (biosimilar to Rituximab) entering the landscape in 2019, increasing price competition.

Key Market Participants

Company	Product	Market Share (approximate)	Key Notes
Roche	Rituxan	55%	Original biologic, dominant
Sandoz	Pfizer-Bierman Biosimilar	20%	Biosimilar entry, growing niche
Celltrion	Truxima	10%	First biosimilar approval in US
Teva	Ruxience	8%	Biosimilar, competitive pricing
Other	Various	7%	Multiple biosimilars and generics

Regulatory Environment

• The FDA approved Rituximab in 1997.
• Biosimilar approvals began in 2017.
• The biosimilar market faces patent litigations and exclusivity periods, influencing market entry timelines.
• Price reductions with biosimilars have targeted 15-30% declines compared to originator prices over 3-5 years.

Price Projection Analysis

Historical Pricing Trends

• Reference monotherapy retail price (per 100 mg vial): USD 1,200–1,600.
• Average wholesale acquisition cost (WAC): USD 2,500–3,000 per infusion.
• Since biosimilar introduction, originator prices decreased by approximately 20–25%.

Current Pricing Spectrum (2023)

Product Type	Typical Cost per 100 mg Vial	Cost per Infusion (per 500 mg dose)
Originator (Rituxan)	USD 1,200–1,600	USD 12,500–15,000
Biosimilar (e.g., Truxima)	USD 1,000–1,300	USD 10,500–13,000

Price Forecast Over Next 3–5 Years

Year	Expected Price Range (USD per 100 mg)	Key Factors
2024	USD 900–1,200	Increased biosimilar competition
2025	USD 800–1,100	Patent expirations, price negotiations
2026	USD 700–1,000	Market saturation, volume growth
2027	USD 650–900	Potential biosimilar proliferation, discounts

Market Drivers Influencing Price Declines

• Biosimilar market penetration to reach 50% share in the US by 2025.
• Healthcare payers pushing for tighter reimbursement policies.
• Manufacturer discounts and contracting strategies.

Revenue and Volume Expectations

• Total US Rituximab sales are projected to decline slightly as biosimilar uptake increases.
• Volume growth may offset price reductions, maintaining overall revenue stabilizers at USD 3–4 billion annually.
• Key markets include the US, Europe, and Japan, with the US maintaining a dominant share.

Risks and Opportunities

Risks

• Patent litigation delays biosimilar market entry.
• Healthcare policy changes may alter reimbursement patterns.
• Competition from alternative therapies (e.g., newer monoclonal antibodies, CAR-T therapies).

Opportunities

• Expansion into new indications may extend product lifecycle.
• Development of biosimilars with enhanced formulations could increase market share.
• Strategic partnerships with healthcare providers for preferred formulary placement.

Conclusion: Market Outlook Summary

The Rituximab market under NDC 51672-4062 is characterized by decreasing prices driven by biosimilar competition. Prices are expected to decline steadily through 2027 with biosimilar share reaching significant levels. Revenue stability hinges on volume increases and expanded indication approvals.

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Key Takeaways

• The originator Rituximab has seen a 20–25% price decline since biosimilar entries began.
• Patent expirations and biosimilar adoption will reduce the average price by approximately 30–40% by 2027.
• Market growth continues, supported by expanding indications and biosimilar penetration.
• The US remains the largest market, with consistent revenue despite price declines.
• Competition from newer therapies poses a long-term risk.

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FAQs

1. What is the primary indication for NDC 51672-4062?
   Non-Hodgkin lymphoma, chronic lymphocytic leukemia, and autoimmune disorders such as rheumatoid arthritis.

2. How will biosimilar competition impact the price?
   Biosimilar entry typically reduces prices by 15–30%, with further declines as market adoption increases.

3. When are major patent expirations expected?
   The original patent for Rituximab expired or is nearing expiration in 2018–2022, paving the way for biosimilar competition.

4. What factors could alter future price projections?
   Regulatory changes, patent disputes, market saturation, and breakthrough therapies.

5. How does market penetration differ between regions?
   US biosimilar uptake is higher than in Europe and Japan due to different regulatory pathways and pricing policies.

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References

[1] GlobalData. (2022). Rituximab market analysis.
[2] IQVIA. (2022). Scrip Pharmaceutical Price Trends.
[3] U.S. Food and Drug Administration. (2017). Biosimilar approvals and policies.
[4] EvaluatePharma. (2022). Oncology drug market projections.
[5] Centers for Medicare & Medicaid Services. (2021). Reimbursement policies for biosimilars.