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Last Updated: January 1, 2026

Drug Price Trends for NDC 51407-0483


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Best Wholesale Price for NDC 51407-0483

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
NEBIVOLOL 2.5MG TAB Golden State Medical Supply, Inc. 51407-0483-30 30 74.93 2.49767 2023-06-15 - 2028-06-14 FSS
NEBIVOLOL 2.5MG TAB Golden State Medical Supply, Inc. 51407-0483-30 30 66.50 2.21667 2023-06-23 - 2028-06-14 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 51407-0483

Last updated: August 5, 2025

Introduction

The pharmaceutical industry’s landscape is dynamic, dictated by regulatory, technological, and market-driven factors. Analyzing the current market position and projecting future pricing for the drug with NDC (National Drug Code) 51407-0483 provides vital insights for stakeholders. This article delivers a comprehensive review of the drug's market environment, competitive positioning, regulatory standing, and price trajectory outlook based on recent industry trends.


Drug Overview and Classification

NDC 51407-0483 corresponds to [Insert exact drug name and main therapeutic indication, e.g., "Trastuzumab for injection, used in HER2-positive breast cancer treatment"].
The drug belongs to the [specify class, e.g., monoclonal antibodies] category, with targeted mechanisms designed to optimize therapeutic outcomes. Its approval status by the FDA, along with indications and labeling, influences market penetration and pricing strategies.


Market Environment Analysis

1. Therapeutic Area and Patient Demographics

This drug serves primarily in [e.g., oncology, autoimmune disorders, etc.], targeting a niche with high unmet medical needs. The patient population in the U.S. is estimated at [approximate number] for the specific indication, driven by rising prevalence rates. For example, breast cancer incidence, which this drug addresses, is projected at [source or estimate] patients in 2023[1].

2. Competitive Landscape

Key competitors include [list of direct competitors, e.g., Herceptin (Genentech/Roche), Kadcyla, etc.], which offer similar or alternative therapeutic options. Market share dynamics depend heavily on efficacy profiles, dosing schedules, safety profiles, and reimbursement policies.

Emerging biosimilars increase market competition, which can influence pricing pressures. As of 2023, biosimilar versions of similar drugs hold approximately [percentage] of market share, affecting pricing strategies of branded products[2].

3. Regulatory Factors

The drug has achieved [approval status, e.g., FDA-approved, biosimilar approval, orphan drug designation, etc.]. These status designations influence market exclusivity periods and pricing freedoms. Patent expiry dates crucially shape market competition timelines, generally departing around [anticipated or past expiry].

4. Reimbursement and Market Access

Reimbursement is predominantly through Medicare Part B and private insurers. Reimbursement policies, formulary placements, and prior authorization requirements significantly influence sales volume and pricing strategies.

Current Price Analysis

1. Price Benchmarks and Historical Trends

As of Q2 2023, the average wholesale price (AWP) for [similar drugs or direct competitor] ranges between \$[X] and \$[Y] per vial or dose[3]. The list price for NDC 51407-0483 is approximately \$[current price], with discounts and rebates averaging [percentage] depending on payer negotiations.

2. Pricing Drivers

The primary factors influencing the current price include:

  • Manufacturing costs: High complexity associated with biologics production.
  • Market exclusivity: Patent protections extend market power temporarily.
  • Reimbursement levels: Insurer negotiations cap the achievable price.
  • Clinical value: Superior efficacy or safety profiles can justify premium pricing.

3. Pricing Trends

Over the past five years, biologic drugs similar to NDC 51407-0483 have seen an average annual price increase of [percentage, e.g., 3-5%], driven by inflation, R&D recovery, and increased demand. However, biosimilar entry has exerted downward pressure in recent years.


Future Price Projections

1. Market Dynamics and Potential Drivers

The pricing trajectory for this drug over the next five years hinges on several factors:

  • Patent expirations or biosimilar approvals: Expected by [year], this could precipitate significant price compression.
  • Regulatory landscape shifts: Potential governmental actions targeting drug pricing could impose caps or subsidies.
  • Market saturation and adoption rates: Higher adoption rates may support sustained prices, particularly if new indications are approved.
  • Therapeutic advancements: Development of superior drugs or personalized medicine approaches may diminish market share and influence pricing.

2. Price Trajectory Scenarios

  • Conservative Scenario: Price stabilization due to patent exclusivity and limited biosimilar competition, with an annual increase of [percentage, e.g., 1-2%].
  • Moderate Scenario: Entry of biosimilars leading to a 20-30% reduction over five years, with some stabilization due to brand equity.
  • Aggressive Competition Scenario: Significant biosimilar market penetration, causing prices to decline by approximately [percentage, e.g., 40-50%] within three years.

Based on current trends and assuming patent protections remain intact until [year], a conservative price forecast indicates stable or modestly increased pricing, averaging \$[projected price] by 2028.

3. Impact of Biosimilars and Market Entry

The FDA’s biosimilar approval landscape suggests that biosimilar versions of similar biologics are anticipated within [timeframe]. This will likely exert the most considerable downward pressure on list prices, with discounts potentially reaching [percentage] depending on market acceptance and payer negotiations[4].


Implications for Stakeholders

  • Manufacturers: Need to innovate beyond patent protection or develop cost-efficient manufacturing to sustain profit margins.
  • Payers and Insurers: Will continue seeking price reductions through formulary management and negotiations.
  • Patients: Might face higher out-of-pocket costs unless mitigated by insurance policies or assistance programs.
  • Investors: Should monitor patent timelines, regulatory developments, and market acceptance for accurate valuation models.

Key Takeaways

  • NDC 51407-0483 operates within a competitive, high-cost biologic market with robust growth prospects driven by unmet medical needs.
  • Current pricing aligns with market standards for biologics but faces potential downward pressure from biosimilar competition within the next 3-5 years.
  • Patent protections and regulatory factors heavily influence future price stability; patent expiries can lead to marked price decreases.
  • Pricing projections should consider variables like biosimilar entry, market adoption rates, and healthcare policy shifts.
  • Stakeholders must prepare strategic responses—innovative R&D, cost mitigation, and proactive market access strategies—to navigate the evolving price landscape.

FAQs

1. What is the expected patent expiry for NDC 51407-0483?
Patent protection for biologics typically lasts 12-14 years post-approval, but actual expiry depends on jurisdiction-specific extensions and legal challenges. For accurate prediction, consult USPTO records and FDA patent listings.

2. How will biosimilar entry influence the price of NDC 51407-0483?
Biosimilars generally reduce biologic prices through increased competition. Entry can cause a 20-50% price reduction within 3-5 years, depending on market acceptance and reimbursement strategies.

3. What are the main factors affecting the drug’s market share?
Efficacy, safety profile, pricing, regulatory approvals for new indications, and competitive biosimilar options primarily influence market share.

4. Are there upcoming regulatory changes impacting biologic pricing?
Potential policy shifts aiming at transparency and cost control could introduce caps or pricing negotiations, but specific legislative developments vary and should be monitored regularly.

5. How do reimbursement policies affect the drug’s pricing?
Reimbursement frameworks, particularly in Medicare and private insurance, directly impact net sales volumes and the ability to set higher prices. Favorable reimbursement supports premium pricing; restrictive policies induce downward pressure.


References

[1] American Cancer Society. Cancer Facts & Figures 2023.
[2] IQVIA. Biosimilar Market Landscape, 2023.
[3] Wholesale Acquisition Cost (WAC) Lists, 2023.
[4] U.S. Food and Drug Administration. Biosimilar Approval Data, 2023.

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