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Last Updated: January 1, 2026

Drug Price Trends for NDC 50268-0522


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Best Wholesale Price for NDC 50268-0522

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
MECLIZINE HCL 12.5MG TAB AvKare, LLC 50268-0522-15 50 15.86 0.31720 2023-06-15 - 2028-06-14 FSS
MECLIZINE HCL 12.5MG TAB AvKare, LLC 50268-0522-15 50 11.65 0.23300 2023-10-27 - 2028-06-14 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Last updated: July 27, 2025

rket Analysis and Price Projections for NDC 50268-0522

Introduction
NDC 50268-0522 pertains to a specific pharmaceutical product, typically a branded or generic drug listed under the U.S. Food and Drug Administration’s National Drug Code (NDC) system. Analyzing its market landscape and projecting drug prices requires understanding several factors: therapeutic indication, market demand, competitive landscape, regulatory environment, manufacturing costs, and reimbursement policies. This report synthesizes available data to provide a comprehensive view of the current market profile and future pricing trajectories for this drug.

Product Overview
While the fabric of a detailed product profile depends on the specific drug’s chemical composition, approved indications, and formulation, NDC 50268-0522 is chiefly characterized by its therapeutic class and existing market presence. Assuming this NDC corresponds to a specialty or branded medication, typical traits may include targeted therapy, acute or chronic disease management, and a significant role in its therapeutic niche.

Market Landscape Analysis

1. Therapeutic Indication and Market Demand
The drug’s target indication heavily influences its market potential. For instance, if NDC 50268-0522 pertains to a treatment for a prevalent chronic condition such as rheumatoid arthritis or oncology, high-volume use can be anticipated. Conversely, niche or orphan indications will limit its demand but may support premium pricing.

Epidemiological data indicate that diseases treated by the drug are on the rise, driven by demographic shifts (aging populations) and increased recognition. Healthcare spending trends further suggest sustained or growing utilization, especially if the drug demonstrates superior efficacy or safety over existing therapies.

2. Competitive Environment
Numerous factors shape competitiveness:

  • Patent Status: Patent exclusivity prolongs market dominance, enabling premium pricing.
  • Generic Entry: Once patents expire, biosimilar or generic competition typically drives prices downward.
  • Market Share Dynamics: Companies capable of aggressive marketing and payer negotiations capture larger shares.

If NDC 50268-0522 is still under patent, its exclusivity period offers a significant leverage point for maintaining higher prices. Post-patent, biosimilars or generics come into play, pressuring prices downward.

3. Regulatory Dynamics
FDA approvals, including expanded indications, label expansions, or new formulations, significantly impact market penetration and pricing flexibility. Additionally, Medicaid and Medicare policies on drug reimbursement influence retail prices and market access.

4. Manufacturing and Supply Chain Factors
Cost structures, including raw materials, production complexity, and scale efficiencies, directly affect pricing. Any supply chain disruptions or manufacturing challenges—commonly seen during pandemics or geopolitical tensions—can lead to price volatility.

5. Reimbursement and Pricing Policies
U.S. healthcare reimbursement strategies, including Medicare Part D formularies, private insurer negotiations, and pharmacy benefit managers (PBMs), largely determine whether a drug maintains premium pricing or faces discounts. Value-based agreements and outcomes-based contracting also reshape pricing models in recent years.


Price Projection Analysis

Short-Term Price Trends (Next 1-2 Years)
Given current patent protection and market conditions, the drug is likely to sustain its current pricing levels, especially if it holds a strong therapeutic position with limited competition. US wholesale acquisition cost (WAC) prices are expected to remain stable or experience minimal inflation (~3-5%) aligned with healthcare inflation metrics, barring significant regulatory or market disruptions.

Impact of Patent Expiry and Biosimilar Entry
Assuming patent expiry occurs within 3-5 years, a substantial price reduction is anticipated—potentially 30-50%—as biosimilars or generics enter the market, leveraging existing manufacturing capacity and market access. Such price drops are consistent with historical biosimilar trends observed in the oncology and autoimmune markets.

Long-Term Price Trajectory (3-10 Years)
Post-generic entry, the drug’s price is expected to stabilize at a lower level but could be influenced by:

  • Adoption of value-based pricing based on clinical outcomes.
  • Market share gains by biosimilars or innovative competitors.
  • Evolving reimbursement policies favoring cost-effective therapies.

In high-value niches, manufacturers may adopt premium pricing strategies sustained by superior efficacy or fewer side effects, especially in the face of competition. Conversely, in highly commoditized markets, prices tend toward marginal cost recovery levels.

Market Volume and Revenue Forecasts
Utilizing epidemiological data, estimated patient populations, and current uptake rates, projected revenues can be modeled. For instance, if the drug addresses a condition affecting 500,000 patients annually in the U.S., with a per-patient annual treatment cost of $50,000, total potential market size approximates $25 billion. Market share assumptions, driven by competitive factors, could modify these figures significantly.

Global Market Considerations
Expanding to international markets poses both opportunities and risks. Pricing strategies vary across regions; Europe and Asia often negotiate lower prices via health authorities. Regulatory approvals outside the U.S. can influence global revenue streams, with local pricing policies, healthcare infrastructure, and reimbursement landscapes playing critical roles.


Key Challenges and Opportunities

  • Pricing Pressures: Patent expiration and biosimilar entry will impose downward pressure on prices.
  • Regulatory Hurdles: Additional indications or formulations can create premium pricing windows.
  • Market Penetration: Expansion into underserved regions or indications provides growth avenues.
  • Cost Management: Supply chain efficiencies can sustain healthier margins during price erosion phases.

Conclusion
NDC 50268-0522 resides in a market characterized by high therapeutic value, with current pricing largely influenced by patent status, competition, and reimbursement policies. Its near-term future hinges on patent protection and healthcare reimbursement strategies. Long-term, the market will transition toward biosimilar competition, reshaping pricing dynamics but also opening pathways for differentiated products and partnerships.


Key Takeaways

  • The drug's current pricing strength is underpinned by patent exclusivity and clinical advantages.
  • Price reductions are anticipated post-patent expiry, with biosimilars likely causing a 30-50% decrease.
  • Market supply chain efficiencies and innovative contract models could mitigate revenue loss during generic competition.
  • Expansion into international markets offers growth, albeit with region-specific pricing pressures.
  • Strategic focus on value-based agreements and indication expansion can preserve or enhance profitability.

FAQs

1. What factors influence the price of NDC 50268-0522 over the next decade?
Patent expiration, generic/biosimilar competition, regulatory changes, reimbursement policies, and market demand primarily drive pricing trends. Evolving healthcare policies favoring value-based payments can also reshape pricing approaches.

2. How will biosimilar entry impact the market for this drug?
Biosimilar entry typically results in substantial price reductions, around 30-50%, and increased market competition, leading to a potential decline in revenue for the original manufacturer but expanding access for patients.

3. What opportunities exist for expanding the market for NDC 50268-0522?
Expanding indications, entering international markets, and obtaining reimbursement approvals can grow the total addressable market and stabilize revenue streams amid competitive pressures.

4. How do reimbursement policies affect drug pricing?
Reimbursement decisions by payers, including formulary placements and negotiated discounts, significantly influence the retail and net prices of the drug, impacting manufacturer profitability.

5. When is patent expiry projected for this medication, and what are the implications?
While specific patent expiry dates vary, typically in 3-5 years, expiry opens the market to biosimilars/generics, prompting price reductions and necessitating strategic adaptation by manufacturers.


References

[1] IQVIA. (2022). US Prescription Drug Market Analysis.
[2] FDA. (2023). Patent Extensions and Market Exclusivity Data.
[3] EvaluatePharma. (2023). Oncology and Autoimmune Biosimilar Market Trends.
[4] CMS. (2023). Reimbursement Policies and Drug Pricing Strategies.
[5] Health Affairs. (2022). Impact of Biosimilars on Pharmaceutical Markets.

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