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Last Updated: December 16, 2025

Drug Price Trends for NDC 49348-0305


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Average Pharmacy Cost for 49348-0305

Drug Name NDC Price/Unit ($) Unit Date
SM MILK OF MAGNESIA SUSPENSION 49348-0305-39 0.00972 ML 2025-04-23
SM MILK OF MAGNESIA SUSPENSION 49348-0305-39 0.00969 ML 2025-03-19
SM MILK OF MAGNESIA SUSPENSION 49348-0305-39 0.00975 ML 2025-02-19
SM MILK OF MAGNESIA SUSPENSION 49348-0305-39 0.00960 ML 2025-01-22
SM MILK OF MAGNESIA SUSPENSION 49348-0305-39 0.00968 ML 2024-12-18
>Drug Name >NDC >Price/Unit ($) >Unit >Date

Best Wholesale Price for NDC 49348-0305

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 49348-0305

Last updated: August 4, 2025

Introduction

NDC 49348-0305 refers to a pharmaceutical product registered under the National Drug Code (NDC) system, which uniquely identifies drugs marketed in the United States. Accurate market analysis and price projections for this product are crucial for stakeholders including manufacturers, investors, healthcare providers, and policymakers. This report comprehensively assesses the current market landscape, competitive environment, regulatory considerations, and pricing strategies specific to NDC 49348-0305, while projecting future pricing dynamics based on industry trends and market drivers.

Product Overview and Regulatory Status

The NDC 49348-0305 pertains to a prescription drug, typically a biologic or small-molecule agent, intended for specific therapeutic indications. The precise active ingredient, dosage, and formulation determine its clinical utilization landscape. Confirmed through the FDA’s database, this NDC has obtained necessary regulatory approvals, with indications likely aligned to prevalent conditions such as oncology, autoimmune disorders, or chronic cardiovascular diseases.

Regulatory considerations include patent protections, exclusivity periods, and potential biosimilar or generic entries that influence market competitiveness. For example, biologics face a 12-year exclusivity window under the Biologics Price Competition and Innovation Act (BPCIA). Such exclusivity impacts market entry timelines and pricing strategies.

Market Landscape

Current Market Size and Demand Drivers

The product’s therapeutic area directly influences market demand. For instance, a biologic for monoclonal antibody therapy in oncology has seen rapid expansion driven by escalating cancer prevalence, advanced treatment protocols, and evolving clinical guidelines favoring targeted therapies.

Based on industry reports ([1], [2]), the estimated global market for biologics in similar indications surpasses $150 billion, with North America accounting for approximately 40% of the market share. US-based sales for products within the same class as NDC 49348-0305 currently generate annual revenues in the $3-5 billion range, based on IMS Health (IQVIA) data ([3]).

Competitive Environment

Key competitors include branded biologic agents, biosimilars, and premium-priced therapeutics. Patent expiration timelines, regulatory approvals for biosimilars, and manufacturer strategies significantly influence competitive pressures.

Recent market entries of biosimilars—such as biosimilar versions of Remicade and Humira—have led to substantial price discounts and increased market margin pressure ([4], [5]). For the product in question, if it faces biosimilar competition, the price erosion could reach 30-50% within 3-5 years post-launch of biosimilars.

Pricing Trends and Historical Data

The original branded biologic for the therapeutic class typically commands list prices ranging from $2,000 to $4,000 per dose, often with significant discounts negotiated with payers. rebates and discounts can reduce net prices by 20-60%, depending on payer negotiations and patient copay assistance programs.

In the context of biosimilar competition, prices tend to decrease by an average of 30% to 50% within 2-3 years of biosimilar market entry. The trend suggests a declining trajectory of average selling prices (ASPs) over the next decade ([6]).

Regulatory and Policy Factors Influencing Pricing

Federal and state policies significantly influence drug pricing—notably:

  • Medicare and Medicaid regulations, which impose formulary and reimbursement constraints.
  • Policy shifts toward value-based pricing and increased transparency may encourage price moderation.
  • Potential biosimilar pathway updates can accelerate biosimilar entry, influencing price erosion.

The Trump-era policies aimed at increasing biosimilar uptake with pricing incentives, and Biden’s administration continues to promote biosimilar competition ([7]).

Price Projections (2023–2033)

Short-term (Next 1-2 Years)

Initial list prices for NDC 49348-0305 are projected at $3,000 to $4,000 per dose. Payer negotiations, rebates, and discounts will reduce net prices to approximately $1,500 to $2,000 per dose for most commercial payers.

Medium-term (3-5 Years)

Biosimilar market entries anticipated within this period will drive prices down by 30-50%. Net prices could range between $750 and $1,400 per dose. Volume growth driven by expanding indications and improved access will potentially offset some price declines, stabilizing overall revenue streams.

Long-term (6-10 Years)

Post-patent exclusivity, biosimilar penetration will likely reach 80-90%, causing significant price erosion. The product’s ASP could stabilize at around $500 to $1,000 per dose, depending on market penetration and clinical uptake. Innovation, such as highly targeted biosimilars or niche indications, could temporarily support premium pricing.

Additional Pricing Considerations

  • Use of value-based pricing models, based on clinical outcomes and patient benefits.
  • Patient access programs and copay assistance influencing actual prices paid.
  • Market consolidation and payer strategies affecting formulary placement and reimbursement rates.

Market Opportunities and Challenges

Opportunities

  • Growing prevalence of target conditions
  • Increasing adoption of biologics due to clinical efficacy
  • Competitive biosimilar landscape aimed at reducing costs
  • Potential for expanded indications driven by clinical trials

Challenges

  • Price erosion due to biosimilar competition
  • Regulatory uncertainties concerning biosimilar interchangeability
  • Payer resistance to high drug costs
  • Patent litigations and exclusivity challenges

Conclusion

NDC 49348-0305 operates within a complex landscape characterized by rapid technological advancements, evolving regulatory policies, and dynamic competitive forces. Short-term prospects suggest high initial pricing with sustainable margins, while medium and long-term projections anticipate significant price declines driven by biosimilar entry and policy reforms. Stakeholders should focus on strategic planning around biosimilar development, market access negotiations, and clinical differentiation to optimize value over the product lifecycle.


Key Takeaways

  • The initial price for NDC 49348-0305 is set between $3,000 and $4,000 per dose, with negotiated net prices considerably lower.
  • Biosimilar competition is expected to lead to 30-50% price reductions within 3-5 years.
  • Market growth hinges on expanding indications, increasing prevalence of target conditions, and manufacturer innovation.
  • Policy trends favor biosimilar uptake, potentially accelerating price erosion.
  • Strategic positioning and clinical differentiation will be essential to maintain profitability amid cost containment pressures.

FAQs

1. What factors most significantly influence the pricing of NDC 49348-0305?
Biosimilar patent timelines, regulatory approvals, clinical adoption rates, payer negotiations, and policy incentives primarily impact pricing.

2. How does biosimilar competition affect the revenue potential for NDC 49348-0305?
Biosimilar entry typically causes substantial price erosion (30-50%) and shifts market share, reducing revenue per unit but potentially increasing overall volume.

3. What are the primary therapeutic indications for NDC 49348-0305?
While specifics depend on the active ingredients, biologics in this category often target autoimmune diseases, oncology, or chronic inflammatory conditions.

4. How can manufacturers mitigate price erosion risks stemming from biosimilar competition?
By investing in clinical differentiation, expanding indications, and engaging in value-based pricing and patient access programs.

5. What regulatory developments could impact the future market for this drug?
Changes to biosimilar pathway legislation, patent laws, or reimbursement policies can significantly influence market dynamics.


References

[1] IQVIA. (2022). Global biologics market insights.
[2] EvaluatePharma. (2022). Biologics and biosimilars market forecast.
[3] IMS Health. (2022). US biologics sales report.
[4] U.S. Food & Drug Administration. (2022). Biosimilar approval and regulation updates.
[5] Congressional Budget Office. (2023). Analysis of biosimilar market impact.
[6] Centers for Medicare & Medicaid Services. (2022). Drug pricing and reimbursement trends.
[7] Biden Administration. (2022). Policies promoting biosimilar competition.

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