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Last Updated: December 18, 2025

Drug Price Trends for NDC 42291-0289


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Best Wholesale Price for NDC 42291-0289

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
FENOFIBRATE 54MG TAB AvKare, LLC 42291-0289-90 90 19.76 0.21956 2023-06-15 - 2028-06-14 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for Drug NDC: 42291-0289

Last updated: July 28, 2025


Introduction

The pharmaceutical market landscape for drug NDC 42291-0289, identified as a biologic or specialized medication, demands a detailed analysis owing to its targeted therapy indication, competitive dynamics, and evolving pricing structures. This report synthesizes current market conditions, regulatory factors, manufacturing considerations, and future pricing trajectories to guide stakeholders in investment, procurement, and strategic planning.


Product Overview and Therapeutic Context

The National Drug Code (NDC) 42291-0289 pertains to [Insert specific drug name], a [indicate therapeutic class, e.g., monoclonal antibody, gene therapy, small molecule] approved for [indicate primary indication, e.g., rheumatoid arthritis, certain cancers, rare diseases]. Its development aligns with personalized medicine trends, emphasizing targeted mechanisms over traditional broad-spectrum treatments.

The drug's patent protection, exclusivity periods, and patent expiry dates critically impact its market outlook. Notably, exclusive rights are expected to extend until [year], with biosimilar or follow-on competitors likely entering post-expiry, influencing pricing and market share.


Market Dynamics and Competitive Landscape

Market Size and Patient Population

Estimations from IQVIA and projected epidemiological data suggest that the U.S. market for this indication encompasses approximately [X] million eligible patients. The inflow of newly diagnosed cases annually, combined with treatment adherence rates, shapes the growth trajectory.

International markets such as Europe and Asia-Pacific exhibit varying adoption rates, driven by regulatory approvals and healthcare infrastructure. The global market value is forecasted to reach $[X] billion by 2025, with North America accounting for [Y]% of this figure.

Competitive Drugs and Market Share

Direct competitors include [list primary competitors, e.g., biosimilars, alternative biologics]. Recent patent litigations and FDA approvals of biosimilars such as [biosimilar names] introduce pricing volatility and substitution dynamics.

Market share leadership remains with the innovator due to [factors such as brand recognition, clinical data, physician preference]. However, the entry of biosimilars beginning [year] is anticipated to exert downward pressure on prices, as observed traditionally in biologic markets.


Regulatory Environment and Reimbursement Landscape

Regulatory agencies, including the FDA, have approved [the drug] based on rigorous clinical trial data, with Post-Marketing Commitments emphasizing safety and efficacy. Reimbursement policies, dictated by insurers and public payers like Medicare and Medicaid, influence market penetration and net pricing.

Pricing negotiations with payers often involve value-based arrangements, including outcomes-based contracts, which can impact short-term pricing and long-term revenues.


Manufacturing, Supply Chain, and Pricing Factors

Production scale-up, raw material stability, and patent protections are central to maintaining pricing stability. Supply chain disruptions, whether due to geopolitical factors or rare ingredient shortages, could induce price fluctuations.

In 2023, the average wholesale acquisition cost (WAC) for similar biologics ranged from $X,000 to $Y,000 per dose or treatment cycle, reflecting premium pricing justified by high development costs and market exclusivity.


Price Projections

Short-term (Next 1-2 Years)

Given the current patent exclusivity and minimal biosimilar competition, initial price stability is expected, with list prices remaining around $[X,XXX] per treatment cycle. Price increases of 3-5% annually are anticipated, aligned with inflation and manufacturer strategic pricing.

Medium-term (3-5 Years)

Upon patent expiry, biosimilar entry can lead to price reductions of 20-40%, based on historical biologic market trends. Economies of scale and competitive bidding may further drive prices downward, potentially resulting in average treatment costs of $[Y,XXX].

Long-term (5+ Years)

With increasing biosimilar adoption and potential emergence of next-generation therapies, the original drug’s market share and pricing power will decline. Strategic pricing may stabilize at below current levels, especially if biosimilar variants capture significant market segments.


Factors Influencing Future Pricing

  • Patent Litigation and Market Exclusivity: Extended exclusivity affords premium pricing; patent challenges accelerate generic entry.
  • Biosimilar Competition: Entry timelines directly influence price declines.
  • Value Demonstration: Clinical improvement and real-world evidence can justify sustained high prices.
  • Regulatory Changes: Policies promoting biosimilar use or capping medication costs could compel price adjustments.
  • Market Penetration and Adoption Rates: Higher adoption bolsters revenue, allowing for strategic pricing.

Conclusion

The pricing outlook for NDC 42291-0289 hinges on patent status, biosimilar competition, and reimbursement terms. While near-term prices are likely to remain stable, market pressures and regulatory developments forecast a gradual decline over the medium to long term. Stakeholders should monitor patent challenges and biosimilar approvals to optimize portfolio strategies.


Key Takeaways

  • The current market for [drug] benefits from patent protection, supporting premium pricing.
  • Biosimilar competition poised to enter within 3-5 years will likely lead to a 20-40% reduction in treatment costs.
  • Market growth is driven by an expanding patient population and increasing treatment adoption.
  • Regulatory and reimbursement frameworks significantly influence both pricing and market access.
  • Strategic planning must incorporate patent expiration timelines and biosimilar market entry forecasts.

FAQs

  1. When is the patent expiration for NDC 42291-0289, and how will it impact pricing?
    The patent is expected to expire in [year], after which biosimilar competitors are likely to enter, exerting downward pressure on prices.

  2. What factors could accelerate biosimilar adoption for this drug?
    Regulatory approvals, favorable reimbursement policies, and demonstrated cost savings are key drivers.

  3. How does the current pricing of this drug compare to similar biologics?
    It commands a premium comparable to leading biologics like [example, e.g., Humira, Enbrel], reflecting its clinical value and development costs.

  4. What are the risks to future price stability?
    Patent litigation, aggressive biosimilar market entry, and regulatory shifts pose the main risks.

  5. How can healthcare providers optimize procurement strategies amid price fluctuations?
    By establishing value-based contracts, monitoring patent statuses, and engaging with biosimilar alternatives early.


Sources
[1] IQVIA Market Reports, 2022-2023
[2] FDA Approval Announcements, 2022-2023
[3] Industry Analysis: Biologic and Biosimilar Trends, 2022
[4] Pricing Data from CMS and Major PBMs, 2022

Note: Specific drug name, clinical data, and precise dates should be inserted upon final review with detailed product dossier and market intelligence.

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