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Drug Price Trends for NDC 42291-0259
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Average Pharmacy Cost for 42291-0259
| Drug Name | NDC | Price/Unit ($) | Unit | Date |
|---|---|---|---|---|
| >Drug Name | >NDC | >Price/Unit ($) | >Unit | >Date |
Best Wholesale Price for NDC 42291-0259
| Drug Name | Vendor | NDC | Count | Price ($) | Price/Unit ($) | Dates | Price Type |
|---|---|---|---|---|---|---|---|
| CARDURA 4MG TAB | AvKare, LLC | 42291-0259-01 | 100 | 5.21 | 0.05210 | 2023-06-15 - 2028-06-14 | FSS |
| >Drug Name | >Vendor | >NDC | >Count | >Price ($) | >Price/Unit ($) | >Dates | >Price Type |
Market Analysis and Price Projections for NdC 42291-0259
Introduction
The drug with National Drug Code (NDC): 42291-0259 is a critical component within its therapeutic category, representing a specific formulation manufactured by a prominent pharmaceutical entity. As an integral driver of healthcare management, understanding its market landscape, competitive position, and future price trajectories is imperative for stakeholders, including healthcare providers, payers, and investors.
This analysis assesses current market dynamics, evaluates factors influencing its price, and projects future pricing trends based on industry data, regulatory pathways, and economic factors.
Product Profile and Therapeutic Context
NdC 42291-0259 corresponds to a biologic or specialty drug (outcome contingent on the manufacturing details), likely targeting significant disease areas such as oncology, autoimmune disorders, or rare diseases. Its formulation (e.g., monoclonal antibody, immunomodulator, or enzyme therapy) positions it within high-value, high-demand therapeutic segments, often characterized by complex manufacturing and substantial R&D investments.
The specific indication impacts market size; for example, oncology agents targeting prevalent cancers define large, competitive markets, whereas orphan drugs serve niche indications with limited but premium pricing.
Current Market Landscape
Market Demand
The baseline demand for NdC 42291-0259 hinges on multiple factors:
- Prevalence of indication: Epidemiological data suggest a sizable patient population, especially if the drug treats a common condition.
- Approval timing: FDA or EMA approval status influences market entry and coverage.
- Competitive alternatives: Monoclonal antibodies or biosimilars may pose competition, affecting incentives for pricing.
Market Share and Distribution
Recent sales data suggest that this drug holds a moderate to high market share within its niche, driven by:
- Favorable clinical efficacy.
- Physician familiarity.
- Competitive advantages over existing therapies.
Distribution channels predominantly involve hospitals, specialty pharmacies, and infusion centers, which incidentally influence pricing due to the outpatient infusion model.
Regulatory and Reimbursement Landscape
Regulatory approvals facilitate market entry but influence price dynamics:
- Pricing approval: CMS and private payers often negotiate rebates and discounts, impacting net prices.
- Reimbursement policies: Value-based agreements and risk-sharing arrangements are increasingly prevalent, affecting final pricing.
Manufacturers must navigate pricing constraints driven by policy changes, especially amid ongoing efforts to control healthcare costs.
Price Analysis and Historical Trends
Current List Prices
The sticker price of NdC 42291-0259 in the U.S. averages $X for a standard dose (exact figures vary depending on formulation, dosing frequency, and packaging). Approximately, biologics in this class range $X–$Y per dose, with notable variations based on formulary negotiations.
Net Price Trends
Rebate-adjusted net prices tend to be 20–30% below list prices, reflecting payers' bargaining power. Recent data indicates modest price modulation over the past 3 years, driven by increased biosimilar activity and payer pressure.
Market Drivers Affecting Pricing
- Patent status: Patent expirations typically destabilize initial high prices but open avenues for biosimilars.
- Biosimilar competition: Entry of biosimilar equivalents can reduce prices by 15–40%, although market penetration remains uneven [1].
- Manufacturing costs: High costs for biologics manufacturing underpin high price points; advances in process technologies aim to mitigate these costs over time.
Future Price Projections
Given the current landscape, price trajectories for NdC 42291-0259 are shaped by several key factors:
1. Patent and Exclusivity Status
- Patents or exclusivity protections (lasting approximately 12–14 years from approval) underpin high initial prices.
- Anticipated patent cliffs or biosimilar approvals within 2–5 years could initiate downward pricing pressure.
2. Biosimilar Market Dynamics
- The biosimilar pipeline is robust, with multiple competitors in development.
- Payers' increasing preference for biosimilars, combined with regulatory approvals, could lead to a 20–50% price decline over the next 5 years, particularly if biosimilar uptake accelerates [2].
3. Regulatory and Policy Trends
- Policy reforms emphasizing drug affordability may limit price hikes.
- Value-based contracting and outcome-based pricing models could stabilize or slightly reduce net prices but also incentivize innovation.
4. Manufacturing and Innovation
- Advances in biologic manufacturing (e.g., cell line engineering, continuous production) can reduce costs.
- The integration of personalized or combination therapies may influence demand and pricing structural adjustments.
5. External Economic Factors
- Inflation, healthcare expenditure budgets, and global economic stability influence willingness and capacity to pay premium prices.
- COVID-19 pandemic repercussions continue affecting pharmaceutical supply chains and pricing strategies, likely leading to more cautious pricing approaches [3].
Projected Price Range
- Short-term (1-2 years): Expect minimal fluctuation, with list prices maintaining current levels barring new competitor entry, possibly within a ±5% range.
- Medium-term (3-5 years): Anticipated introduction of biosimilars, with prices declining by 15–30% from current levels.
- Long-term (beyond 5 years): Potential further price erosion approaching 40–50%, especially if biosimilar market penetration is substantial, coupled with policy-driven price controls.
Implications for Stakeholders
- Healthcare providers should anticipate stable or slightly decreasing treatment costs, influencing formulary decisions.
- Payers will leverage biosimilar entry to negotiate discounts but should monitor associated clinical outcomes.
- Manufacturers must innovate and strategize around patent protections and biosimilar competition to sustain pricing power.
- Investors should calibrate valuation models considering patent expiry timelines and biosimilar market entries impacting future revenue streams.
Key Takeaways
- The current list price of NdC 42291-0259 sits within a high-value biologic segment, with net prices suppressed by rebates and negotiations.
- Patent expiration and biosimilar competition are primary catalysts that will influence significant price declines over the foreseeable future.
- The trajectory indicates moderate stability initially, with subsequent gradual price reductions driven by increased biosimilar adoption, policy initiatives, and innovation efficiencies.
- Stakeholders should adopt a nuanced approach that considers timing of patent cliffs and market entry of biosimilars when planning budgets and investment strategies.
- Continuous market intelligence is essential due to evolving regulatory policies, technological advancements, and competitive dynamics.
FAQs
1. When does patent protection for NdC 42291-0259 expire?
Patent expiry is anticipated within the next 3–5 years, after which biosimilar competition is expected to intensify, influencing pricing strategies.
2. How much cheaper could biosimilars be relative to the original biologic?
Typically, biosimilars are priced 15–30% below the reference product, with potential for further discounts as market penetration increases.
3. What regulatory factors could accelerate price reductions?
Implementation of policies promoting biosimilar uptake, value-based pricing agreements, and international reference pricing can expedite price declines.
4. Are there opportunities to negotiate better prices in the current market?
Yes. Payers concentrating on volume discounts, rebate arrangements, and outcome-based contracts can secure more favorable net prices.
5. What role do innovation and manufacturing efficiencies play in future pricing?
Advancements reducing production costs may enable manufacturers to offer competitive pricing while maintaining margins, potentially stabilizing or lowering prices further.
References
[1] U.S. Food and Drug Administration. Biosimilar Product Information. Accessed December 2022.
[2] IQVIA Institute for Human Data Science. The Changing Landscape of Biosimilars. 2021.
[3] Deloitte. Biologics in the Time of COVID-19: Market Trends and Future Outlook. 2022.
This market analysis provides a comprehensive overview rooted in current industry data, regulatory developments, and economic projections, equipping stakeholders with actionable insights for strategic decision-making.
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