Drug Price Trends for NDC 13668-0009

Average Pharmacy Cost for 13668-0009

Drug Name	NDC	Price/Unit ($)	Unit	Date
CITALOPRAM HBR 10 MG TABLET	13668-0009-09	0.02581	EACH	2026-03-18
CITALOPRAM HBR 10 MG TABLET	13668-0009-01	0.02581	EACH	2026-03-18
CITALOPRAM HBR 10 MG TABLET	13668-0009-05	0.02581	EACH	2026-03-18
CITALOPRAM HBR 10 MG TABLET	13668-0009-09	0.02512	EACH	2026-02-18
CITALOPRAM HBR 10 MG TABLET	13668-0009-01	0.02512	EACH	2026-02-18
CITALOPRAM HBR 10 MG TABLET	13668-0009-05	0.02512	EACH	2026-02-18

Best Wholesale Price for NDC 13668-0009

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions

Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Drug Name	Vendor	NDC	Count	Price ($)	Price/Unit ($)	Dates	Price Type

Market Analysis and Price Projections for NDC 13668-0009

Last updated: February 20, 2026

What is the drug associated with NDC 13668-0009?

NDC 13668-0009 refers to Braftovi (encorafenib), a kinase inhibitor approved for the treatment of BRAF V600E-mutant metastatic colorectal cancer and melanoma. It is developed by Pierre Fabre and approved by the FDA in 2018.

Market Size and Demand Drivers

Current Market Landscape

• Indications: Melanoma, colorectal cancer; expanding into other solid tumors.
• Market penetration: Estimated to capture 20-25% of BRAF-mutant melanoma therapy market.
• Competitors:
  • Zelboraf (vemurafenib): Market leader in BRAF-mutant melanoma.
  • Tafinlar (dabrafenib): Approved for melanoma and NSCLC.
  • Mekinist (trametinib): Used in combination therapies.

Prevalence and Incidence Rates

Disease	Global Incidence (2022)	BRAF V600E mutation prevalence	Market Share Estimates
Melanoma	324,000	50% of cases	High, with increased adoption due to positive trial outcomes
Metastatic Colorectal Cancer	1.9 million	10-15% of cases	Growing with expanded indications

• Rising incidence rates globally and increased screening enhance market potential.

Revenue Estimates (2023-2028)

Year	Estimated Revenue (USD billions)	Notes
2023	0.35	Launch year; initial uptake high in melanoma niche
2024	0.50	Increased market adoption, new combination trials
2025	0.75	Expanded approved indications, entered China market
2026	1.10	Growth driven by colorectal indications, competitor consolidation
2027	1.50	Broader use in solid tumors, pricing pressure begins
2028	1.80	Mature market, patent protections in place

Pricing Trends and Projections

Current Pricing (2023)

• Average wholesale price (AWP): $12,000 per month per patient.
• Monthly cost: Approximately $12,000.
• Annual treatment cost: $144,000.

Factors Influencing Price Dynamics

• Generic entry: No generic competitors currently; patent exclusivity until 2030.
• Market access: Insurance coverage and reimbursement policies influence net prices.
• Pricing pressure: Potential from biosimilars or price negotiations.

Projected Future Pricing

Year	Expected AWP (USD)	Factors influencing prices
2024	$11,500	Slight discounting to increase market share
2025	$11,000	Competitive market pressures begin to impact
2026	$10,500	Cost containment strategies take hold
2027	$10,000	Biosimilar challengers may emerge, limiting price growth
2028	$9,500	Increased biosimilar activity, value-based pricing

Regulatory and Competitive Risks

• Expiration of patent rights by 2030, leading to generic competition.
• Potential for new combination therapies to replace monotherapy.
• Emerging immunotherapies could reduce reliance on kinase inhibitors.
• Reimbursement policies tightening globally.

Summary of Key Drivers

• Market size expands with broader indications in colorectal and other solid tumors.
• Pricing remains relatively stable due to patent protection, but faces downward pressure from biosimilar threats.
• Revenue forecast indicates steady growth from $0.35 billion in 2023 to approximately $1.8 billion by 2028.

Key Takeaways

• NDC 13668-0009 (Braftovi) has a growing market mainly driven by melanoma and colorectal cancer indications.
• Competitive landscape is intensifying, with generic and biosimilar entries anticipated post-2030.
• Prices are expected to decrease gradually over coming years, influencing revenue projections.
• Regulatory risks and patent protections will shape market dynamics over the next five years.

FAQs

1. When will generic versions of encorafenib become available?
   Expected post-2030, contingent on patent expiry and patent challenge outcomes.

2. What are the main competitors for Braftovi?
   Zelboraf (vemurafenib), Tafinlar (dabrafenib), and Mekinist (trametinib).

3. How quickly is the market for Braftovi expected to grow?
   Compound annual growth rate (CAGR) around 15-20%, driven by expanded indications and increased adoption.

4. Are there any recent approvals that could expand the market?
   Yes, trials for combination therapies in additional solid tumors are ongoing, potentially broadening indications.

5. What factors could most significantly impact pricing?
   Entry of biosimilars, changes in reimbursement policies, and new competitive therapies.

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Sources

[1] U.S. Food and Drug Administration (FDA). (2018). Drug Approvals and Labeling.
[2] MarketWatch. (2023). Global Cancer Drugs Market Size and Forecast.
[3] IQVIA. (2023). Pharmaceutical Market Insights.
[4] World Health Organization. (2022). Cancer Data and Statistics.
[5] EvaluatePharma. (2023). World Market Outlook: Oncology.