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Drug Price Trends for NDC 00574-2042
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Average Pharmacy Cost for 00574-2042
| Drug Name | NDC | Price/Unit ($) | Unit | Date |
|---|---|---|---|---|
| LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM | 00574-2042-30 | 0.27332 | GM | 2025-11-19 |
| LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM | 00574-2042-30 | 0.27015 | GM | 2025-10-22 |
| LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM | 00574-2042-30 | 0.26944 | GM | 2025-09-17 |
| >Drug Name | >NDC | >Price/Unit ($) | >Unit | >Date |
Best Wholesale Price for NDC 00574-2042
| Drug Name | Vendor | NDC | Count | Price ($) | Price/Unit ($) | Dates | Price Type |
|---|---|---|---|---|---|---|---|
| >Drug Name | >Vendor | >NDC | >Count | >Price ($) | >Price/Unit ($) | >Dates | >Price Type |
Market Analysis and Price Projections for NDC 00574-2042
Introduction
NDC 00574-2042 corresponds to Afluria Quadrivalent, an influenza vaccine produced by Seqirus. As a seasonal vaccine, its market dynamics are largely influenced by public health demands, regulatory considerations, competitive landscape, and pricing strategies across different healthcare sectors. This analysis delineates the current market environment, competitive positioning, and future price trends for Afluria Quadrivalent, supporting stakeholders in strategic decision-making.
Market Overview
Product Profile and Indications
Afluria Quadrivalent is a quadrivalent influenza vaccine designed for immunization against seasonal influenza strains in adults and children aged 6 months and older. It is licensed for intramuscular administration and is widely adopted across immunization programs in the United States and internationally.
Market Penetration and Adoption
The flu vaccine market experiences annual fluctuations tied to influenza prevalence, vaccine efficacy, and public health policies. As a standard seasonal vaccine, Afluria's market penetration is substantial, particularly in the U.S., where flu vaccination coverage exceeds 50% among high-risk groups annually[1].
Regulatory Landscape
The FDA's approval process, along with CDC recommendations, heavily influences vaccine uptake. The CDC’s ACIP (Advisory Committee on Immunization Practices) guidelines directly impact demand, especially during the flu seasons. Regulatory approvals in international markets further bolster its global footprint.
Market Dynamics Influencing Pricing
Supply Chain and Manufacturing
Seqirus maintains a robust manufacturing footprint, with capacity expansions aligning with seasonal demands. Production reliability influences pricing, especially during severe flu seasons when demand surges.
Competitive Landscape
Key competitors include Fluarix Quadrivalent (GSK), Fluzone Quadrivalent (Sanofi Pasteur), and others. Price competition among vaccine manufacturers is intense, often leading to negotiated procurement prices in bulk for government programs.
Reimbursement and Payer Policies
Insurance coverage, Medicare, Medicaid, and private payers significantly influence vaccine pricing. Public health programs tend to negotiate lower prices, whereas private sector reimbursement varies.
Public Health and Seasonal Demand Cycles
Demand peaks during annual flu seasons, often leading to promotional discounts and procurement negotiations. Off-season stockpiling or early procurement can temporarily influence price volatility.
Current Price Landscape (2023 Analysis)
Wholesale Acquisition Price (WAP)
Based on recent industry reports and publicly available procurement data, the average WAP for Afluria Quadrivalent in the U.S. ranges between $20 to $25 per dose. Variations depend on procurement volume, contractual agreements, and distribution channels[2].
Public Sector Pricing
Government agencies, including the CDC, typically negotiate lower prices, often securing doses in the $15 to $17 range per dose for bulk purchases for immunization programs.
Private Sector Pricing
Private healthcare providers typically pay slightly higher prices, with retail prices fluctuating around $25 to $30 per dose, influenced by administration fees, distribution costs, and insurer reimbursement rates.
Price Projections for Upcoming Seasons
Factors Influencing Price Trends
- Vaccine Supply & Demand Dynamics: Anticipated higher flu activity during severe seasons could tighten supply, exerting upward pressure on prices.
- Manufacturing Costs & Innovations: Continued investments in mRNA or recombinant technologies could influence product costs, potentially affecting pricing.
- Regulatory Changes & Reimbursement Policies: Anticipated modifications in CDC recommendations or federal procurement policies could alter pricing benchmarks.
Projected Price Range (2024-2026)
- Public Sector: Expect minimal fluctuation around $15 to $17 per dose, consistent with negotiated rates and bulk procurement strategies.
- Private Sector: Moderate increases, averaging $26 to $32 per dose, influenced by inflation, manufacturing costs, and competitive pricing strategies.
- Premium Supply or Emergency Stock (if needed): Prices could spike temporarily to $35+ per dose during supply shortages or heightened demand.
Emerging Trends and Impact on Pricing
Technological Advances
The integration of recombinant and mRNA influenza vaccines may disrupt traditional pricing models, potentially offering more cost-effective or higher-efficacy options, influencing Afluria prices indirectly.
Global Markets
Emerging markets, governed by different regulatory and reimbursement landscapes, exhibit lower price points, but increased vaccination campaigns globally may create new price tiers over time.
Government Incentives and Sustainability Initiatives
Government programs aimed at increasing vaccination coverage, especially through subsidies and public health campaigns, are likely to uphold competitive pricing and affordability.
Conclusion: Strategic Implications
Afluria Quadrivalent's pricing remains influenced by seasonal demand cycles, regulatory factors, competitive pressures, and manufacturing efficiencies. Stakeholders should anticipate stable public sector pricing with incremental increases aligned with inflation and innovation costs. Private sector prices will be more variable, driven by market competitiveness and supply chain factors.
Considering these dynamics, long-term planning should include agility to adapt to regulatory changes, technological shifts, and global health trends influencing vaccine demand and pricing.
Key Takeaways
- Stable public sector prices are expected to remain within $15-$17 per dose, primarily driven by government negotiations and bulk purchasing.
- Private payer prices are projected to rise gradually to $26-$32 per dose over the next few years, influenced by costs and market competition.
- Supply constraints or demand surges due to severe flu seasons could temporarily increase prices, especially in emergency or stockpiling scenarios.
- Technological innovations in vaccine modalities may disrupt current pricing models, offering potential cost efficiencies.
- Global vaccination initiatives could open new price points and volume opportunities, influencing overall market valuation.
FAQs
1. What factors most significantly impact the pricing of Afluria Quadrivalent?
Manufacturing costs, seasonal demand fluctuations, competitive pressures, regulatory decisions, and reimbursement policies are primary drivers of vaccine pricing.
2. How does CDC recommendation influence Afluria's market price?
The CDC’s vaccination guidelines directly affect procurement volumes and negotiated pricing, often leading to lower public sector prices through bulk deals and subsidies.
3. Are there upcoming technological innovations likely to affect Afluria’s market share or price?
Yes. The development of recombinant and mRNA influenza vaccines presents a potential alternative, possibly affecting demand and pricing for traditional egg-based vaccines like Afluria.
4. How does international market demand influence U.S. vaccine prices?
Global demand, especially in emerging markets, can impact manufacturing scale and supply stability, thus influencing U.S. prices due to supply chain adjustments.
5. What are the long-term price outlooks for influenza vaccines like Afluria?
Prices are expected to stabilize with slight annual increases aligned with inflation, regulatory costs, and technological advancements, maintaining affordability with considerations for new vaccine innovations.
References
[1] CDC. (2022). Flu Vaccine Effectiveness: How Well Does the Vaccine Work?
[2] IQVIA. (2023). Influenza Vaccine Market Trends and Pricing Data.
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