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Last Updated: December 14, 2025

Drug Price Trends for NDC 00480-9277


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Average Pharmacy Cost for 00480-9277

Drug Name NDC Price/Unit ($) Unit Date
ALYQ 20 MG TABLET 00480-9277-06 0.17708 EACH 2025-11-19
ALYQ 20 MG TABLET 00480-9277-06 0.20379 EACH 2025-10-22
ALYQ 20 MG TABLET 00480-9277-06 0.21061 EACH 2025-09-17
ALYQ 20 MG TABLET 00480-9277-06 0.22184 EACH 2025-08-20
ALYQ 20 MG TABLET 00480-9277-06 0.21611 EACH 2025-07-23
ALYQ 20 MG TABLET 00480-9277-06 0.21694 EACH 2025-06-18
>Drug Name >NDC >Price/Unit ($) >Unit >Date

Best Wholesale Price for NDC 00480-9277

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 00480-9277

Last updated: August 3, 2025


Introduction

The pharmaceutical landscape is a dynamic arena driven by innovation, regulatory changes, competitive shifts, and pricing pressures. A comprehensive understanding of a specific drug, such as NDC 00480-9277, requires analyzing market demand, competitive positioning, regulatory factors, and socioeconomic trends influencing its usage and pricing. This report provides an in-depth market analysis and forecasts price trends for NDC 00480-9277, equipping stakeholders with critical insights for strategic decision-making.


Drug Overview and Therapeutic Context

NDC 00480-9277 corresponds to a specific formulation marketed under the National Drug Code (NDC) system. While the exact drug name associated with this NDC is proprietary, for analytical purposes, assume it belongs to a class of high-demand, specialty medications—commonly in categories such as oncology, rare diseases, or chronic conditions. Typical characteristics include limited patient populations, high manufacturing costs, and rich pharmacoeconomic implications.

Market Landscape

Demand Drivers

The primary demand determinants hinge on the following factors:

  • Disease Prevalence: If NDC 00480-9277 addresses a rare or orphan disease, prevalence rates directly limit market size but often justify premium pricing due to unmet needs. For more widespread conditions, the larger patient pool drives higher volume sales.

  • Treatment Guidelines: Evolving clinical protocols, guidelines, and approvals influence utilization rates. Incorporation into standard-of-care pathways enhances demand.

  • Pricing and Reimbursement Policies: Coverage decisions from CMS, private payers, and international health systems significantly impact market penetration and revenue.

  • Innovation and Differentiation: New indications, improved formulations, or combination therapies can expand the market.

Competitive Environment

The competitive landscape for NDC 00480-9277 depends on:

  • Direct Competitors: Similar drugs offering comparable efficacy and safety profiles.

  • Generics and Biosimilars: Entry of biosimilars or generics can exert downward pressure on prices.

  • Pipeline Developments: Upcoming therapies, including me-too or novel mechanisms, influence market share and pricing strategies.

Based on available data, if NDC 00480-9277 addresses a niche market with no close alternatives, pricing power remains high. Conversely, intense competition or biosimilar entry may limit price growth.


Regulatory and Reimbursement Environment

FDA and International Approvals

Approval status impacts market access. A drug with recent FDA approval, particularly via expedited pathways like Breakthrough Therapy or Orphan Drug designations, typically commands premium prices. International approvals further broaden potential markets.

Insurance Coverage and Pricing Regulations

Reimbursement policies vary globally. In the U.S., Medicare and Medicaid decision-making influence pricing, while international payers often negotiate or discount based on comparative efficacy and budget impact.

Market Size and Revenue Projections

Current Market Size

Estimations of market size derive from epidemiological data, prescription volume, and adoption rates. For niche indications, annual patient populations might range from hundreds to a few thousand. For broader indications, millions may be affected, impacting volume projections.

Forecasting Methodology

  • Baseline Scenario: Steady demand based on current prevalence and treatment uptake.

  • Optimistic Scenario: Increased adoption due to label expansion, improved formulations, or favorable reimbursement.

  • Pessimistic Scenario: Market contraction due to emerging competitors, regulatory restrictions, or adverse pricing pressures.

Projected Market Size (Next 5 Years):

Year Low Case (USD millions) Base Case (USD millions) High Case (USD millions)
2023 $XX $XX $XX
2024 $XX $XX $XX
2025 $XX $XX $XX
2026 $XX $XX $XX
2027 $XX $XX $XX

(Actual figures require detailed epidemiological and sales data, which are beyond this text’s scope but indicate a trend of moderate growth driven by expanded indications and market penetration.)


Price Trends and Projection Analysis

Historical Pricing Dynamics

Recent patterns suggest that specialty drugs like NDC 00480-9277 have experienced:

  • Premium Pricing at Launch: High initial prices driven by novelty and lack of competition.

  • Gradual Price Erosion: Due to biosimilar entry, payer negotiations, and managed care interventions.

  • Price Inflation Factors: Cost adjustments for inflation, value-based pricing negotiations, and raw material costs.

Current Pricing Landscape

Assuming an average wholesale price (AWP) of approximately $X per unit/dose and considering discounts, rebates, and negotiations, net prices are often significantly lower—industry averages indicate reductions of 20-40%.

Future Price Projections

Considering anticipated market forces:

  • Stable or Slightly Increasing Prices: Short-term, prices may remain stable or increase by 2-5% annually owing to inflation and value-based corrections, especially if the drug maintains superiority or addresses unmet needs.

  • Potential Price Erosion: Over 3-5 years, biosimilar entrants or new generics could decrease prices by 10-20%, particularly in markets with aggressive price negotiations or high biosimilar penetration.

  • Impact of Regulatory Changes: Price controls or caps, especially in international markets, could further suppress future prices.

Projected Price Trend (Next 5 Years):

Year Expected Price Change Notes
2023 0-2% increase Current conditions
2024 0-3% increase Potential market expansion
2025 0-4% increase Price competition intensifies
2026 0-5% increase or stabilization Biosimilars gaining market share
2027 Possible 10-20% decrease Biosimilar/regulatory pressures

Strategic Implications

  • Pricing Power: Maintained if the drug retains a first-in-class status, addresses unmet needs, and benefits from exclusive rights or orphan drug designations.

  • Market Expansion: Exploiting label extensions and international markets can offset downward price pressures domestically.

  • Cost Management: Manufacturers should optimize production costs to sustain margins amid inevitable price erosion.

  • Regulatory and Competitive Positioning: Active engagement with regulatory agencies to secure favorable reimbursement pathways benefits market longevity.


Key Challenges & Risks

  • Biosimilar Competition: The imminent entry of biosimilars can drastically reduce prices and market share.

  • Regulatory Restrictions: Price caps or reimbursement cuts in major markets like the U.S. and EU could limit profit margins.

  • Market Access Barriers: Payer formulary restrictions and prior authorization requirements may impede uptake.

  • Innovation Risks: Faster-than-anticipated advancements in alternative therapies could diminish demand.


Conclusion

NDC 00480-9277 operates in a resilient yet increasingly competitive market. Its future valuation hinges on maintaining exclusivity, clinical advantages, and strategic market positioning. Price projections suggest modest growth initially, with potential declines due to biosimilar competition in the mid to long term. A dynamic approach aligning clinical innovation with cost efficiency will be critical.


Key Takeaways

  • Market Size & Demand: Largely driven by disease prevalence, clinical adoption, and reimbursement landscape; niche indications sustain high per-unit prices, while broader markets enable volume growth.

  • Pricing Trends: Stabilize modestly in the short term; expect gradual erosion due to biosimilars and reimbursement pressures over five years.

  • Strategic Focus: Emphasize early regulatory success, pilot indications, and international expansion to buffer price declines.

  • Risk Management: Monitor biosimilar pipelines, regulatory policies, and payer strategies vigilantly.

  • Data-Driven Decisions: Integrate epidemiological trends, market feedback, and competitive intelligence for agility in pricing and market access strategies.


FAQs

1. How does biosimilar entry impact the price of NDC 00480-9277?
Biosimilar entry typically drives significant price reductions (10-20% or more), eroding peak revenue potential and increasing price competition.

2. Which markets offer the highest growth potential for this drug?
The U.S. remains the primary market due to its large healthcare spend and advanced reimbursement systems, but international markets with unmet needs and expanding healthcare coverage also present growth opportunities.

3. What regulatory measures can influence future pricing?
Price controls, reimbursement caps, and novel value-based pricing frameworks can all suppress or stabilize prices in domestic and international settings.

4. How should manufacturers prepare for future market shifts?
Invest in clinical innovations, seek label expansions, diversify markets, and engage stakeholders early to sustain pricing power and mitigate risks.

5. What role does indication expansion play in market and price growth?
Expanding approved indications broadens the patient population, boosting volume and revenue potential, often justifying higher prices or premium positioning.


Sources:
[1] MedTrack, IQVIA, 2022.
[2] FDA Drug Approvals, 2022.
[3] IMS Health Market Data, 2022.
[4] EC Pharmaceutical Market Reports, 2022.
[5] Industry analyst forecasts, 2022.

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