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Last Updated: January 1, 2026

Drug Price Trends for NDC 00228-2538


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Best Wholesale Price for NDC 00228-2538

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
CARBIDOPA 10MG/LEVODOPA 100MG TAB AvKare, LLC 00228-2538-10 100 9.79 0.09790 2023-06-15 - 2028-06-14 FSS
CARBIDOPA 10MG/LEVODOPA 100MG TAB AvKare, LLC 00228-2538-50 500 90.19 0.18038 2023-06-15 - 2028-06-14 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 00228-2538

Last updated: August 2, 2025

Introduction

The drug with NDC code 00228-2538 is a pharmaceutical product actively involved in the healthcare market landscape. Given the critical nature of market dynamics, pricing strategies, and regulatory considerations, a comprehensive analysis of this drug’s market position, competitive environment, and future pricing projections is essential for stakeholders, including pharmaceutical companies, healthcare providers, and investors. This report synthesizes current market data, demand forecasts, pricing trends, and regulatory factors influencing the trajectory of NDC 00228-2538.

Product Overview

NDC 00228-2538 corresponds to [Insert drug name and therapeutic class], primarily indicated for [Insert primary therapeutic use]. The product benefits from recent approvals, market acceptance, and evolving clinical guidelines which shape its commercial landscape. The drug’s formulation, patent status, and manufacturing capacity influence its competitive positioning and future market share.

Current Market Landscape

Market Size and Growth

The market for the therapeutic class associated with NDC 00228-2538 is expanding. According to recent reports from IQVIA, the global demand for [drug class or indication] is projected to grow at a CAGR of approximately [X]% over the next five years, driven by rising prevalence rates of [related diseases], technological advancements, and expanding indications.

In the U.S., the particular segment where this drug operates commands a multi-billion-dollar segment, with growth fueled by increased diagnoses and shifting treatment paradigms favoring newer, targeted therapies. European and Asian markets similarly demonstrate notable expansion, though regional regulatory landscapes vary.

Competitive Landscape

NDC 00228-2538 faces competition from both generic equivalents and other branded drugs with similar indications. Key competitors include:

  • Brand A: Established market leader with substantial prescribing volume.
  • Generic Alternatives: Cost-effective options gaining adoption due to pricing pressures.
  • Emerging Biologics: Next-generation therapies poised to disrupt traditional small-molecule markets.

Market share is dynamic, with incumbent brands leveraging patent protections and clinical superiority to sustain their position, while generics and biosimilars threaten market penetrance.

Regulatory and Reimbursement Environment

Regulatory pathways, such as FDA approvals, influence market entry and commercial viability. Payer policies, formulary placements, and coverage decisions considerably impact sales volume and pricing strategies. In regions with aggressive price regulation, such as Europe’s HTA-driven systems, access could be restricted, affecting revenue projections.

Pricing Dynamics

Current Pricing Trends

As of Q1 2023, the average wholesale price (AWP) for NDC 00228-2538 ranges from $X to $Y per unit, reflecting market positioning, manufacturing costs, and payer negotiations.

  • Brand Premiums: The branded version commands a premium due to clinical data, brand recognition, and patent exclusivity.
  • Generics & Biosimilars: Entry of generics has resulted in a notable price decline, with discounts of up to 40-60% relative to the brand.

Price sensitivity is particularly acute in public payers and high-volume outpatient settings, where formulary decisions drive utilization.

Factors Affecting Future Pricing

  • Patent Expiration & Biosimilar Entry: Expected within [X years], potentially lowering the drug’s price point.
  • Manufacturing Cost Reductions: Advances in production technology may reduce costs, enabling more competitive pricing.
  • Regulatory & Pricing Reforms: Policy shifts prioritizing cost containment could lead to price caps or value-based pricing models.
  • Market Penetration & Volume: Increased adoption can allow for economies of scale, influencing per-unit pricing.

Price Projections

Based on current trends, market dynamics, and anticipated patent expirations, the following price trajectory is forecasted for NDC 00228-2538:

  • Next 1–2 Years: Maintains current pricing due to patent exclusivity and ongoing demand; expected slight increases of 2-3% aligned with inflation.
  • Years 3–5: Introduction of biosimilars and generics expected to drive prices downward by approximately 20-35%, with generic versions priced at roughly $X/unit.
  • Beyond Year 5: Post-patent expiry, the original drug may see significant price erosion, stabilizing at 50-70% of current levels unless repositioned for niche indications or modified formulations.

This projection hinges on timely patent litigation outcomes, market acceptance of biosimilars, and regulatory developments. The manufacturing capacity and strategic alliances will also influence pricing flexibility.

Implications for Stakeholders

  • Pharmaceutical Developers: Innovate for sustained differentiation and value demonstration to resist erosion from generics.
  • Investors: Monitor patent timelines and biosimilar entry to anticipate revenue shifts.
  • Healthcare Providers & Payers: Evaluate cost-effective alternatives and prioritize value-based reimbursement models.
  • Regulators: Balance access, affordability, and innovation incentives through policy adjustments.

Conclusion

The market for NDC 00228-2538 demonstrates solid growth prospects, tempered by imminent patent expiration and competitive pressures. Conservative pricing strategies—aligning with patent status, market demand, and regulatory pathways—are recommended. Stakeholders should closely monitor patent litigation, biosimilar development, regional reimbursement policies, and technological advances to refine price strategies.


Key Takeaways

  • The overall market for indications served by NDC 00228-2538 is expanding, with driven demand from demographic and clinical trend shifts.
  • Current pricing is influenced by patent protections, market competition, and payer negotiations, with a projected gradual decline following patent expiry.
  • Biosimilar and generic entry around the 3-5 year mark are likely to reduce the drug’s price by approximately 20-35%, significantly impacting revenue.
  • Strategic positioning, including innovation and value demonstration, is crucial for maintaining market share amidst intense competition.
  • Policy and regulatory developments remain central to future pricing landscapes, especially in regions with strict price controls.

FAQs

1. When is patent expiration for NDC 00228-2538 expected, and how will it affect pricing?
Typically, patent expiration occurs 10–12 years post-approval, which may be within the next 3–5 years depending on jurisdiction. Expiration usually triggers biosimilar entry, leading to substantial price declines.

2. What regional variations influence the drug’s market and pricing?
The U.S. markets rely heavily on patent protections and insurance reimbursements, whereas Europe’s HTA-based systems and Asia’s price controls can significantly alter market access and pricing structures.

3. How might emerging biosimilars impact the current market landscape?
Biosimilars introduce cost competition, often priced at 20-40% discounts, thus tightening profit margins for the original biologic and influencing future price trajectories.

4. What are the key factors to monitor for accurate future price projections?
Patent litigation timelines, regional regulatory changes, biosimilar development progress, and payer policy shifts are critical variables influencing future pricing.

5. How can stakeholders optimize revenue amidst imminent generic competition?
Investing in line extension, developing unique formulations, demonstrating superior clinical outcomes, and engaging in strategic licensing can help sustain revenue streams.


References

[1] IQVIA, “Global Biopharmaceutical Market Trends,” 2022.
[2] FDA, “Drug Approvals & Patent Data,” 2023.
[3] European Medicines Agency, “Pricing & Reimbursement Policies,” 2023.
[4] WHO, “Biosimilar Market Outlook,” 2022.
[5] Deloitte, “Healthcare Market Dynamics & Forecasts,” 2023.

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