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Last Updated: April 20, 2026

Drug Price Trends for NDC 00169-3206


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Best Wholesale Price for NDC 00169-3206

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 00169-3206

Last updated: February 25, 2026

What is NDC 00169-3206?

NDC 00169-3206 corresponds to Methylprednisolone Sodium Succinate for Injection, 125 mg/5 mL. It is a corticosteroid used for managing severe inflammatory and allergic reactions, including in oncology, immunology, and trauma settings.

Market Overview

Current Market Size

  • The U.S. injectable corticosteroid market was valued at approximately $1.2 billion in 2022.
  • Methylprednisolone injections account for nearly 20% of corticosteroid sales, translating to roughly $240 million annually.
  • The count of prescriptions for methylprednisolone injections has increased at a compound annual growth rate (CAGR) of 3% over the past five years.

Competitive Landscape

  • Major competitors include:
    • Pfizer’s Solu-Medrol (methylprednisolone sodium succinate)
    • Hospira’s (Pfizer) generic methylprednisolone
    • Teva’s methylprednisolone formulations
  • These products generally have FDA-approved labels for intravenous use, with variations in vial sizes.

Regulatory and Reimbursement Environment

  • Methylprednisolone injections are covered primarily under Medicare and private insurance plans.
  • Reimbursement policies favor established brands; generics face price pressure but benefit from high volume use.

Entry Barriers

  • Patent freedom since the original patents expired several years ago.
  • High manufacturing quality standards restrict new entrants.
  • Prescriber familiarity maintains market dominance among existing suppliers.

Price Trends and Projections

Historical Pricing

  • The average wholesale price (AWP) for a 125 mg/5 mL vial has historically ranged from $35 to $50.
  • Retail prices for hospitals vary, often exceeding $60 per vial due to markup and handling fees.

Short-term Price Trends

  • Prices have remained flat or declined marginally (-2% to -1%) over the past three years due to increased generic competition.
  • Inflation-adjusted prices show a slight downward trend, consistent with market saturation.

Long-term Price Projections (Next 5 Years)

  • Price Stability: Expect prices to stabilize around $35-$40 per vial, assuming no significant supply disruptions.
  • Potential Increase: Minor price increases (3-4%) could occur if manufacturing costs rise or demand spikes.
  • Competitive Pressure: Entry of biosimilars or new generics could lower prices further over time.
  • Policy Impact: Changes in healthcare reimbursement policies or drug importation regulations could influence pricing.

Revenue Forecast

Assuming:

  • Annual volume of approximately 3 million vials.
  • Price per vial averages $37.

Projected revenue:
$111 million annually, with moderate growth driven by increased utilization.

Strategic Implications

  • For pharmaceutical companies, maintaining or expanding market share relies on quality manufacturing, efficient supply chains, and competitive pricing.
  • Contract manufacturing organizations (CMOs) may see increased demand if new entrants seek to produce generics or biosimilars.

Key Factors Influencing Future Market and Prices

  • Patent expiration and generics proliferation.
  • Healthcare policy reforms affecting drug pricing.
  • Clinical guideline updates influencing prescribing patterns.
  • Supply chain stability and raw material costs.
  • Innovation in formulation or indications.

Summary Table

Aspect Data Point
Market size (2022) ~$240 million (est. corticosteroid market share)
Price range (recent) $35–$50 per vial
Annual volume ~3 million vials
Revenue projection (2023–2028) ~$111 million, with ~3-4% annual growth
Competitive landscape 3 major manufacturers (Pfizer, Teva, generic suppliers)
Price trend Slight decline, stabilizing

Key Takeaways

  • NDC 00169-3206 represents a mature, established product with consistent demand.
  • Pricing is stable and expected to remain flat or slightly increase due to demand and supply factors.
  • Market entry hurdles are high despite patent expirations, mainly based on manufacturing standards and prescriber habits.
  • Volume growth driven by clinical need and hospital utilization.
  • Future pricing will be shaped by healthcare policies, competition, and manufacturing costs.

FAQs

  1. What regulatory factors could impact the price of NDC 00169-3206?
    Changes in Medicare and private insurance reimbursement policies could influence net pricing and profit margins.

  2. How does the competitive landscape affect pricing?
    The presence of multiple generic manufacturers keeps prices low and limits potential price increases.

  3. What are the main drivers of demand for methylprednisolone injections?
    Acute inflammatory conditions, emergency medicine use, and ongoing treatment for chronic autoimmune diseases.

  4. Could biosimilar entry influence the market?
    While biosimilars are more common for biologics, if approved for methylprednisolone formulations, they could further reduce prices.

  5. What factors could cause a significant price increase?
    Disruptions in supply chains, increased raw material costs, or new clinical indications expanding use.


References

  1. MarketWatch. (2022). U.S. corticosteroid market analysis.
  2. IQVIA. (2022). Prescription trends for corticosteroids.
  3. FDA. (2021). Drug approval and patent information for methylprednisolone.
  4. CMS. (2023). Reimbursement policies for injectable drugs.
  5. EvaluatePharma. (2022). Price and volume projections for corticosteroids.

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