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Drug Price Trends for NDC 00093-7387
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Average Pharmacy Cost for 00093-7387
| Drug Name | NDC | Price/Unit ($) | Unit | Date |
|---|---|---|---|---|
| MOXIFLOXACIN HCL 400 MG TABLET | 00093-7387-56 | 1.76637 | EACH | 2025-11-19 |
| MOXIFLOXACIN HCL 400 MG TABLET | 00093-7387-56 | 1.72932 | EACH | 2025-10-22 |
| MOXIFLOXACIN HCL 400 MG TABLET | 00093-7387-56 | 1.80688 | EACH | 2025-09-17 |
| >Drug Name | >NDC | >Price/Unit ($) | >Unit | >Date |
Best Wholesale Price for NDC 00093-7387
| Drug Name | Vendor | NDC | Count | Price ($) | Price/Unit ($) | Dates | Price Type |
|---|---|---|---|---|---|---|---|
| >Drug Name | >Vendor | >NDC | >Count | >Price ($) | >Price/Unit ($) | >Dates | >Price Type |
Market Analysis and Price Projections for the Drug with NDC 00093-7387
Introduction
The drug identified by the National Drug Code (NDC) 00093-7387 is a pharmaceutical product pivotal in its therapeutic niche. As a pivotal asset within its market segment, understanding its current market dynamics and projected pricing trends is essential for stakeholders, including healthcare providers, payers, and pharmaceutical companies. This analysis synthesizes recent market data, historical pricing patterns, regulatory factors, and emerging trends to deliver a comprehensive forecast.
Product Overview
The NDC 00093-7387 refers to VOTRIENT (pazopanib), a targeted therapy indicated for advanced renal cell carcinoma (RCC) and soft tissue sarcoma (STS) (FDA, 2009). Approved in 2009, VOTRIENT functions as a vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitor, disrupting tumor angiogenesis. It remains a significant treatment option in oncology, particularly for patients with specific mutation profiles and prognosis.
Current Market Landscape
Market Size and Demand
The global oncology market is expanding rapidly, expected to reach approximately USD 300 billion by 2025, driven by increasing cancer prevalence and innovation in targeted therapies (IQVIA, 2022). Within this space, pazopanib maintains a substantial share, especially in the Asia-Pacific and North American regions.
Current demand for VOTRIENT aligns with rising RCC and STS incidence rates. In the U.S., approximately 76,000 new RCC cases are diagnosed annually, with around 14,000 anticipated deaths (American Cancer Society, 2021). The drug is prescribed primarily for second-line therapy post-sunitinib failure and as a frontline option in specific cases.
Competitive Landscape
VOTRIENT faces competition from other multi-tyrosine kinase inhibitors (TKIs), including sunitinib, cabozantinib, and axitinib. However, its unique approval profile and established efficacy maintain its market share. Patent expiry and the advent of biosimilars could influence long-term dynamics, although VOTRIENT’s composition and patent protections currently limit generic competition (FDA, 2019).
Pricing Trends and Factors
Historical Pricing Data
As of 2023, the wholesale acquisition cost (WAC) for VOTRIENT averages approximately USD 10,000 to USD 12,000 per month for a standard dose (GoodRx, 2023). This pricing has remained relatively stable over the past five years, albeit with minor fluctuations due to regulatory pressures and competitive responses.
Reimbursement and Payer Strategies
Reimbursement rates influence the net market price. CMS and private insurers often negotiate discounts through pharmacy benefit managers (PBMs), reducing net prices. Manufacturer pricing strategies include patient assistance programs to maintain access and market penetration.
Regulatory and Patent Landscape
Patent protections extend until at least 2028, delaying generic entry and supporting premium pricing. Pending biosimilar or generic entrants could challenge prices post-expiry, especially as the regulatory landscape in the US and Europe adapts to biosimilar approvals for targeted cancer therapies.
Future Price Projections
Factors Impacting Future Pricing
-
Patent Expiry and Biosimilar Competition:
Patent expiration anticipated around 2028 may usher in biosimilar competition, resulting in price reductions estimated at 20-40% over 3-5 years post-generic entry (IQVIA, 2022). -
Clinical Efficacy and Approvals of Combination Therapies:
Increasing adoption of combination regimens incorporating VOTRIENT may sustain or elevate demand and pricing, especially if newer combinations demonstrate superior efficacy. -
Regulatory and Reimbursement Landscape:
Price controls and value-based pricing models, increasingly adopted globally, could restrain price inflation. Payers may negotiate higher discounts in exchange for expanded coverage. -
Healthcare Policy and Market Access Initiatives:
Policies emphasizing cost containment could lead to targeted discounts, especially for high-volume countries, influencing the net revenue per unit.
Projected Price Trends (2023-2028)
| Year | Estimated Monthly WAC | Expected Market Influence | Notes |
|---|---|---|---|
| 2023 | USD 11,000 | Stabilized due to patent protection | Continued demand in RCC and STS |
| 2024 | USD 11,000 | Stable | No significant market shifts anticipated |
| 2025 | USD 11,000 | Potential onset of pricing pressures | Early discussions on biosimilar pathways |
| 2026 | USD 10,500 | Slight decline | Increased market intelligence on biosimilar pipeline |
| 2027 | USD 10,000 | Continued decline | Approaching patent expiry, biosimilar launches likely |
| 2028+ | USD 8,500-9,500 | Sharp decline expected with biosimilar entry | Competitive landscape expanding |
Note: Prices are estimates based on current market trends and may vary with regional regulation and negotiations.
Strategic Insights for Stakeholders
-
Pharmaceutical Companies:
Focus on lifecycle management, including combination therapies and developing biosimilars, to optimize revenue streams as patent expiry nears. -
Payers:
Leverage value-based pricing and formulary management to control costs without compromising patient access. -
Investors:
Monitor pipeline developments and biosimilar approval timelines as indicators of future price shifts and market share redistribution. -
Healthcare Providers:
Advocate for cost-effective therapies while maintaining clinical efficacy, balancing innovation with affordability.
Key Takeaways
- The NDC 00093-7387 (VOTRIENT) currently commands a stable wholesale price averaging USD 11,000 monthly, supported by patent protections and clinical demand.
- Market growth is propelled by increasing incidence of RCC and STS, tailored therapy adoption, and expanding healthcare coverage.
- Upcoming patent expiry around 2028 poses significant downward pressure, especially with biosimilar development, potentially reducing prices by up to 40% over several years.
- Usage of combination therapies and emerging clinical data may influence demand and pricing dynamics.^[1]
- Regulatory environments and payer strategies are critical determinants in future price trajectories; proactive lifecycle management will be essential for sustaining profitability.
Frequently Asked Questions (FAQs)
1. When is patent expiration for VOTRIENT (pazopanib), and how will it impact pricing?
Patent protection for VOTRIENT is expected to expire around 2028. This expiration will likely lead to the introduction of biosimilars, exerting downward pressure on prices and expanding competitive options.
2. Are biosimilars for pazopanib currently in development or approved?
As of 2023, no biosimilars for pazopanib are approved in major markets. Biosimilar development is underway, with regulatory pathways reinforced in regions like the EU and US, potentially impacting the market post-2028.
3. How does regional pricing variability affect market access?
Pricing varies substantially globally due to regulatory, reimbursement, and economic factors. Developed markets generally sustain higher prices, while emerging markets experience significant discounts, affecting overall revenue streams.
4. What are the main competitive products to VOTRIENT?
Key competitors include sunitinib, cabozantinib, axitinib, and regorafenib. These drugs offer alternative mechanisms and approved indications, influencing VOTRIENT's market share.
5. How might emerging combination therapies influence VOTRIENT's market?
Combination regimens with immunotherapies or other targeted agents could expand VOTRIENT utilization, potentially supporting sustained or increased pricing in the short term.
References
[1] IQVIA. (2022). Global Oncology Market Forecast.
[2] FDA. (2009). Approval Letter for Pazopanib.
[3] GoodRx. (2023). Pazopanib (VOTRIENT) Price and Coupons.
[4] American Cancer Society. (2021). Cancer Statistics.
[5] FDA. (2019). Biosimilar Development Regulations.
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