Last updated: February 21, 2026
What Is the Drug Associated with NDC 00093-0753?
NDC 00093-0753 corresponds to Trazodone Hydrochloride tablets, 50 mg. Trazodone is primarily prescribed for depression and off-label for sleep disorders.
Market Size and Demand
Current Utilization
- Trazodone ranks among the top 50 antidepressants in the U.S., with an estimated 20 million prescriptions annually.
- Prescriptions increased by approximately 8% annually over the past five years, driven by off-label use for insomnia.
Key Market Players
- Major manufacturers include Teva Pharmaceuticals, Mylan (now part of Viatris), and Apotex.
- Brand equivalent: Desyrel (Wyeth/AmerisourceBeee), though generics dominate the market.
Competitive Landscape
| Manufacturer |
Market Share (Estimate) |
Pricing Strategy |
Distribution Channels |
| Teva |
40% |
Competitive pricing, bulk discounts |
Pharmacies, hospitals |
| Mylan/Viatris |
30% |
Price penetration, rebate programs |
Retail chains, mail-order |
| Others |
30% |
Variable |
Specialty pharmacies |
Regulatory and Market Trends
- The generic market for trazodone is mature.
- Increasing off-label usage for sleep disorders correlates with stable demand.
- The patent expired in the early 2000s; no current patent restrictions influence pricing.
Price Projections
Current Pricing
- Wholesale Acquisition Cost (WAC): Approximately $0.10-$0.20 per tablet (50 mg).
- Average retail price: Around $0.30-$0.50 per tablet.
- Bulk procurement can reduce unit cost to below $0.10 per tablet.
Short-Term Outlook (Next 1-2 Years)
- Stable prices due to high generic competition.
- Slight downward pressure on wholesale prices, potentially reaching $0.08-$0.10 per tablet in large-volume purchases.
Long-Term Outlook (3-5 Years)
- Prices will likely remain stable barring supply chain disruptions or policy changes.
- Incremental cost reductions expected as manufacturers streamline manufacturing.
Factors Affecting Pricing and Market Dynamics
- Reimbursement policies: Changes in insurance coverage could impact demand.
- Supply chain issues: Disruptions could temporarily increase prices.
- Emerging formulations: Development of extended-release versions or combination products could shift market share.
Strategic Implications
- High generic competition limits profit margins for manufacturers.
- Companies should focus on cost optimization and supply chain resilience.
- Off-label uses necessitate monitoring for potential regulatory or legal shifts affecting prescribing practices.
Key Takeaways
- NDC 00093-0753 (Trazodone 50 mg) is part of a saturated generic market with stable demand driven by depression treatment and off-label sleep aid use.
- Price per tablet remains low, averaging around $0.30 retail, with potential reductions in wholesale rates.
- Market growth is modest; competition keeps prices suppressed.
- Potential future shifts depend on regulatory changes and supply chain stability.
FAQs
1. How does the generic status affect pricing for NDC 00093-0753?
Generic status drives price reductions due to increased competition, resulting in lower profit margins for manufacturers.
2. Are there upcoming regulatory changes that could influence market dynamics?
Current regulations do not indicate imminent changes specific to trazodone, but broader drug pricing reforms could impact reimbursements and supply chain logistics.
3. What are the main factors influencing demand for trazodone?
Demand stems from depression treatment, off-label sleep aid use, and prescribing habits, with off-label sleep use accounting for a significant share.
4. How does supply chain stability impact prices?
Disruptions can cause temporary price increases or shortages, but overall prices tend to remain stable given market saturation.
5. What are potential future product developments?
Extended-release formulations or combination therapy could alter market share, but current market remains predominantly generics.
References
- IQVIA. (2022). Pharmaceutical Market Data.
- FDA. (2022). Drug Approvals and Labeling.
- Statista. (2022). Antidepressant Prescription Trends in the U.S.
- Mergent Online. (2022). Market Share Reports.
- CMS. (2022). Medicare and Reimbursement Policies.
