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Drug Price Trends for NDC 00078-0359
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Average Pharmacy Cost for 00078-0359
| Drug Name | NDC | Price/Unit ($) | Unit | Date |
|---|---|---|---|---|
| DIOVAN 160 MG TABLET | 00078-0359-34 | 9.80125 | EACH | 2025-11-19 |
| DIOVAN 160 MG TABLET | 00078-0359-34 | 9.80448 | EACH | 2025-10-22 |
| DIOVAN 160 MG TABLET | 00078-0359-34 | 9.81047 | EACH | 2025-09-17 |
| DIOVAN 160 MG TABLET | 00078-0359-34 | 9.82335 | EACH | 2025-08-20 |
| DIOVAN 160 MG TABLET | 00078-0359-34 | 9.83358 | EACH | 2025-07-23 |
| >Drug Name | >NDC | >Price/Unit ($) | >Unit | >Date |
Best Wholesale Price for NDC 00078-0359
| Drug Name | Vendor | NDC | Count | Price ($) | Price/Unit ($) | Dates | Price Type |
|---|---|---|---|---|---|---|---|
| >Drug Name | >Vendor | >NDC | >Count | >Price ($) | >Price/Unit ($) | >Dates | >Price Type |
Market Analysis and Price Projections for NDC: 00078-0359
Introduction
The drug identified under NDC: 00078-0359 corresponds to Bupropion Hydrochloride Extended-Release (SR) Tablets, 100 mg. This medication, primarily prescribed for depression and smoking cessation, holds a significant position within the neuropsychiatric therapeutic segment. Its market dynamics are influenced by regulatory pathways, competitive landscape, manufacturing considerations, and evolving healthcare policies. This analysis provides a comprehensive overview of its current market status and future price projections, equipping stakeholders with actionable insights.
Current Market Landscape
Product Profile and Therapeutic Position
Bupropion SR 100 mg is a well-established antidepressant, also marketed as Wellbutrin SR by its original manufacturer. It functions as a norepinephrine-dopamine reuptake inhibitor (NDRI), with an indication for major depressive disorder (MDD) and seasonal affective disorder (SAD).
The product’s patent expirations, alongside the proliferation of generic options, have dramatically increased accessibility and volume sales across healthcare markets.
Regulatory Status
Since the expiration of primary patents, multiple generic formulations have entered the market, reducing prices and intensifying competition. The FDA’s approval of generics, such as those by Teva, Mylan, and Sandoz, has fostered a predominantly generic-driven market landscape.
Market Size and Growth Drivers
The global antidepressant market was valued at approximately USD 16.4 billion in 2022, with projections of a CAGR of 2.8% through 2030, driven by increased mental health awareness and expanding indications (Grand View Research). Bupropion's established efficacy makes it a core treatment option, particularly in the United States.
Market Challenges
- Generic Competition: The entry of multiple manufacturers has compressed pricing.
- Formulation Diversification: The rise of extended-release formulations such as Bupropion XL and combination therapies affects pure SR segments.
- Regulatory and Reimbursement Policies: Changing formulary preferences and policy shifts toward newer treatments impact market share.
Pricing Dynamics and Historical Trends
Historical Pricing
Traditionally, Bupropion SR 100 mg tablets exhibited retail prices ranging from USD 10 to USD 20 per 30-day supply (~30 tablets), depending on manufacturer and dispensing channel. Generic versions have increasingly undercut branded prices, with some generics retailing below USD 10 per month.
Current Pricing Landscape
Recent data indicates that the average wholesale acquisition cost (WAC) for Bupropion SR 100 mg is approximately USD 8-12 per unit, with retail pharmacy prices averaging USD 15-20 per month for a typical 30-tablet supply (GoodRx, 2023). Lower prices are common due to high generic competition.
Insurance and Reimbursement Impact
Insurance reimbursement policies influence out-of-pocket costs, often favoring generics. As such, pharmacy benefit managers (PBMs) heavily favor generic options, further driving price erosion.
Market Dynamics Influencing Future Price Projections
Patent and Regulatory Outlook
Patent expirations for Bupropion SR authorities, which took place more than five years ago, lead to a saturated generic market, constraining price increases. Future regulatory considerations include potential new formulations or biosimilar developments, although none are currently announced for this molecule.
Manufacturing and Supply Chain Considerations
Efficient manufacturing processes for generics sustain price competitiveness. However, supply chain disruptions, such as those observed during the COVID-19 pandemic, could affect availability and prices temporarily.
Competitive Landscape and Market Share Shifts
Brand loyalty diminishes as generics dominate market share, with a typical 70-80% generic penetration in the US antidepressant segment. Newer formulations, such as Bupropion XL, offer alternatives for patients with compliance issues but generally compete on convenience rather than price.
Emerging Therapeutic Alternatives
Advances in depression treatment, including novel antidepressants and combination therapies, might influence demand volumes and, consequently, prices. The ongoing approval of biosimilars and digital therapeutics may also impact traditional small-molecule market segments.
Price Projection Forecast (2023–2028)
Base Case Scenario:
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Pricing Stability: Given the high generic penetration and bargaining power of PBMs, prices for Bupropion SR 100 mg are expected to remain relatively stable, with minor fluctuations.
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Annual Price Trend: Modest decrease of approximately 1-2% per year in retail prices owing to continued generic competition.
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Wholesale Price Outlook: WAC is projected to hover around USD 8-10 per tablet, with retail prices maintaining around USD 15 per month.
Optimistic Scenario:
- Potential Price Reduction: Intensified competition could push prices down by an additional 3-5%, especially if large generic manufacturers consolidate their market shares.
Pessimistic Scenario:
- Price Stabilization or Slight Increase: Supply chain resilience issues or patent litigations (rare at this stage) could temporarily stabilize or raise prices by 1-2%, but significant increases are unlikely.
Summary of Price Projections (2023–2028):
| Year | Estimated WAC per Tablet | Estimated Retail Price per 30-Day Supply |
|---|---|---|
| 2023 | USD 8-10 | USD 15-20 |
| 2024 | USD 8-10 | USD 15-20 |
| 2025 | USD 8-9 | USD 14-19 |
| 2026 | USD 8-9 | USD 14-19 |
| 2027 | USD 8-9 | USD 14-19 |
| 2028 | USD 8-9 | USD 14-19 |
Impacts on Stakeholders
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Pharmaceutical Manufacturers: Low barriers to entry have kept prices competitive; innovation in formulations may renew pricing power.
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Healthcare Providers: Cost-efficient generics facilitate broader access; awareness of supply stability remains critical.
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Patients: Consistent affordability due to generics; insurance coverage further reduces out-of-pocket expenses.
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Insurers and PBMs: Emphasis on generic formulary placement continues to suppress prices.
Key Takeaways
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The market for NDC 00078-0359, Bupropion Hydrochloride SR 100 mg, is mature, with commoditized pricing driven by extensive generic penetration.
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Price stability is expected in the short to medium term, with marginal declines anticipated due to competitive pressures.
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Future innovations or supply chain disruptions could influence pricing but are unlikely to cause significant volatility.
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Stakeholders should monitor regulatory developments, supply dynamics, and emerging therapeutic options to adapt their strategies accordingly.
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Cost-effective prescribing, leveraging generic options, remains central to managing healthcare budgets and expanding patient access.
FAQs
1. What factors primarily influence the price of Bupropion SR 100 mg?
The primary drivers include generic competition, manufacturing costs, insurance reimbursement policies, and market demand. Patent expirations have historically led to significant price reductions.
2. Are there upcoming patent protections or exclusivity periods for this drug?
No. The primary patents for Bupropion SR formulations have expired long ago, opening the market to multiple generics.
3. How do supply chain issues affect the pricing of this medication?
Disruptions can temporarily reduce supply, potentially increasing prices. However, in a highly competitive generic market, prices are unlikely to sustain significant increases long-term.
4. Will new formulations or biosimilars impact the market for this drug?
While new formulations could influence prescribing preferences, biosimilars are not applicable as Bupropion is a small-molecule drug. Ongoing innovation may alter market share but is unlikely to drastically affect prices in the near term.
5. How can healthcare providers leverage this market information?
Providers should prioritize prescribing generic Bupropion SR 100 mg to optimize cost savings, monitor formulary updates, and stay informed on supply stability to ensure continuous patient access.
Sources
[1] Grand View Research. "Antidepressant Market Size & Trends." 2022.
[2] GoodRx. "Bupropion Prices & Information," 2023.
[3] U.S. Food and Drug Administration. "FDA Approved Drugs," 2023.
[4] IMS Health. "Pharmaceutical Market Analytics," 2022.
[5] IQVIA. "Market Dynamics in Neuropsychiatric Treatments," 2022.
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