Last updated: February 16, 2026
What Is NDC 00024-5926?
NDC 00024-5926 identifies a specific prescription drug. According to the FDA’s National Drug Code directory, it corresponds to Dextromethorphan Hydrobromide, 60 mg/10 mL oral syrup. It is primarily used as a cough suppressant in over-the-counter and prescription formulations.
Market Size and Demand Drivers
Current Market Overview
The overall cough and cold market in the U.S. was valued at approximately $4.8 billion in 2022, with non-prescription products accounting for around 70% of sales, or roughly $3.36 billion (source: IQVIA). The prescription segment for dextromethorphan, though smaller, is driven by formulations for pediatric and special populations with cough-related indications.
Demand Trends
- Seasonality: Peak demand occurs in fall and winter, coinciding with cold and flu seasons.
- Prescribing Patterns: Although OTC products dominate, certain prescriptions distribute formulations via clinics and hospitals for pediatric care or specific off-label uses.
- Regulatory Changes: The FDA's 2020 advisory against giving high doses to children affects prescription volumes but increases reliance on OTC options.
Competitive Landscape
Key players in patent-protected and generic markets include Johnson & Johnson, Perrigo, and generic manufacturers. The market is primarily mature, with limited innovation since the active ingredient is well established.
Price Trends and Projections
Historical Pricing
- Average Wholesale Price (AWP): For the 60 mg/10 mL syrup, AWP has fluctuated between $5.50 and $7.00 per 10 mL unit over the past three years.
- Retail Price: Retail prices are approximately $8.00 to $10.00 per 10 mL bottle, depending on location and pharmacy chain.
Factors Impacting Prices
- Generic Competition: Multiple generics have entered the market, exerting downward pressure.
- Supply Chain Dynamics: Amazon, major distributors, and pharmacy benefit managers influence pricing.
- Regulatory Changes: FDA advisories and potential scheduling adjustments could influence prices, though none are imminent for this drug.
Price Projections (Next 3-5 Years)
| Year |
Estimated Range (per 10 mL) |
Basis |
| 2023 |
$7.00 – $9.00 |
Current market trends, generic competition ongoing |
| 2024 |
$6.50 – $8.50 |
Continued generic proliferation, demand stability |
| 2025 |
$6.00 – $8.00 |
Potential new entrants, price elasticity effects |
| 2026 |
$5.75 – $7.75 |
Market saturation, minor price reductions |
Prices are expected to decline gradually due to intensified generic competition, with stabilization around $6.00 to $8.00 per 10 mL by 2026.
Regulatory and Policy Impact
No recent proposals or regulations directly target dextromethorphan formulations that notably alter the market landscape. The FDA’s 2020 advisory against high-dose use in children influences prescribing but does not impact OTC pricing significantly.
Key Market Opportunities and Risks
- Opportunities: Expansion of formulation options (e.g., sustained-release), targeted pediatric formulations, and combination products.
- Risks: Regulatory shifts, increased generic competition, and potential market saturation.
Conclusion
The drug corresponding to NDC 00024-5926 operates in a mature, highly competitive market. The price trajectory will likely decline modestly, reflecting persistent generic entry and steady demand patterns. The overall market remains stable in the near term, with limited growth projections.
Key Takeaways
- The product is a standard OTC cough suppressant with a well-established market presence.
- Prices have stabilized around $8.00 per 10 mL, with potential decreases to approximately $6.00 to $7.75 by 2026.
- The market is driven by seasonal demand, generic competition, and regulatory influences.
- Limited innovation and regulatory changes are expected to impact pricing or market size significantly.
FAQs
1. How does the presence of generics influence the drug’s price?
Generic entrants push prices downward by increasing supply and market share, reducing brand-name product premiums.
2. Are there upcoming regulatory changes that could affect this drug's market?
No current proposals or regulations specifically target dextromethorphan formulations; existing policies mainly influence prescribing habits.
3. What opportunities exist for market expansion?
Formulations targeting pediatric patients, extended-release versions, and combination products present potential growth avenues.
4. How does seasonal demand affect pricing?
Prices may spike slightly during peak cold and flu seasons but generally remain within a stable range due to constant generic competition.
5. What factors could cause prices to deviate from projections?
Regulatory actions, supply chain disruptions, or major patent litigations could alter price trajectories.
Sources
[1] IQVIA, "U.S. Cold and Cough Market Review," 2022.
[2] FDA, "Drug Safety Communications," 2020.
[3] DrugPatentWatch, "Dextromethorphan Market Data," 2023.
[4] GoodRx, "Average Retail Prices," 2023.
