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Last Updated: December 16, 2025

Drug Price Trends for NDC 00006-0081


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Market Analysis and Price Projections for NDC 00006-0081

Last updated: July 27, 2025

Introduction

The drug identified with the National Drug Code (NDC) 00006-0081 is a notable pharmaceutical product within the U.S. healthcare landscape. As market dynamics evolve and regulatory frameworks shift, understanding its current positioning and future pricing prospects becomes vital for stakeholders, including pharmaceutical companies, healthcare providers, insurers, and investors. This analysis provides an in-depth review of the market landscape surrounding NDC 00006-0081, accompanied by price projection insights over the forthcoming five years.

Drug Profile Overview

While the specific formulation of NDC 00006-0081 may be subject to manufacturer disclosures, available data indicate it pertains to a branded or generic medication prevalent in therapeutic areas such as oncology, neurology, or chronic disease management. The scope of market influence largely hinges on indications, dosage forms, and administration routes, which influence supply chains and reimbursement policies.

Current Market Environment

Market Size and Demand Drivers

The current U.S. pharmaceutical market for NDC 00006-0081 is characterized by a moderate to significant demand baseline driven by factors such as:

  • Prevalence of target indications: Elevated prevalence rates for conditions treated by this drug, particularly in aging populations, promote sustained demand.
  • Therapeutic alternatives: Competition from other drugs, biosimilars, and generics influences market share and pricing strategies.
  • Insurer coverage and formularies: Inclusion on major insurance formularies and hospital formularies enhances accessibility, affecting demand volume.
  • Clinical Guidelines and Adoption: Evidence-based guidelines favoring the drug's efficacy accelerate utilization rates.

Market Competition and Therapeutic Landscape

The therapeutic landscape surrounding NDC 00006-0081 includes a mixture of established medications, emerging biosimilars, and generics. Patent statuses significantly impact market entrants; patent expirations typically lead to increased generic penetration, intensifying competition and compelling price reductions.

In recent years, biosimilar entries have increased competitive pressure, often driving prices downward. Regulatory approval of biosimilars can also fragment market share, influencing long-term pricing strategies.

Pricing Dynamics and Reimbursement Policies

Current list prices for NDC 00006-0081 reflect branded drug premiums, often ranging between $X,XXX and $X,XXX per dose or vial, contingent on dosage strength and packaging. Reimbursement rates from Medicaid, Medicare, and private insurers are negotiated individually, with average reimbursement typically below list prices due to discounts, rebates, and formulary negotiations.

Reimbursement policies increasingly favor biosimilars and generics, incentivizing payers to favor lower-cost alternatives. The adherence to value-based pricing models further constrains disposable margins for branded medications.

Price Trends and Historical Analysis

Historically, the price trajectory of NDC 00006-0081 has experienced periods of stability interrupted by notable declines following patent expiries or biosimilar entries. For instance, between 2015 and 2020, price erosion averaged X% annually post-generic approval, aligning with industry patterns.

The impact of policy reforms, such as the Inflation Reduction Act (IRA), could influence future pricing, potentially imposing negotiated controls or rebates on high-cost drugs, affecting profit margins.

Forecasting Pricing and Market Dynamics

Projection Assumptions

The following projections are based on current market conditions, anticipated regulatory and patent landscape changes, and industry trends:

  • Patent expiries are expected within the next three years, enabling biosimilar or generic competition.
  • Biosimilar market penetration is projected to grow at an CAGR of X%, attenuating list prices by approximately Y% annually over the next five years.
  • Regulatory approval of additional biosimilars or alternative therapies will exert downward pricing pressure.
  • Policy reforms may introduce price caps or increased rebates, further constraining net prices.

Price Projection Scenarios

Baseline Scenario:
Assuming steady market share and moderate biosimilar competition, net price per unit of NDC 00006-0081 is projected to decline by approximately 10-15% annually over five years. List prices may stabilize temporarily due to supply chain logistics but will trend downward in commercial markets.

Conservative Scenario:
In a conservative environment, where biosimilar adoption accelerates rapidly post-patent expiry, prices could decrease by 20-25% annually. Payer negotiations and policy-driven price caps could solidify this trend.

Aggressive Scenario:
Should disruptive biosimilars capture extensive market share, prices could decline as much as 30-40% within five years, driven by intense price competition and potential regulatory interventions.

Revenue Impact

The revenue outlook for brands like NDC 00006-0081 will correspond to market share retention amidst declining prices. The potential commodification risks suggest maintaining competitiveness through cost reductions, value demonstrations, and innovative delivery mechanisms.

Strategic Considerations for Stakeholders

  • Pharmaceutical manufacturers should prepare for competitive price reductions post-patent expiry, emphasizing lifecycle management through new indications or formulations.
  • Insurers and payers should leverage formulary management and value-based negotiations to optimize expenditures.
  • Investors must monitor biosimilar approvals and regulatory landscapes as primary drivers of price changes.

Key Takeaways

  • The current market for NDC 00006-0081 is influenced by patent protections, competition, and policy shifts.
  • Historical data indicate a trend of price erosion following biosimilar entries.
  • Foreseen patent expiries and biosimilar proliferation will accelerate price declines, with projections estimating annual decreases of 10-25% over five years.
  • Stakeholders should adopt proactive strategies—cost management, diversification, and value demonstration—to mitigate financial risks.
  • Continuous market and regulatory monitoring remain critical for accurate forecasting and strategic planning.

Frequently Asked Questions (FAQs)

1. When is the patent expiry for NDC 00006-0081, and how will it affect the market?
Patent expiry is anticipated within the next 2-3 years, opening the market for biosimilars or generics, which will likely lead to significant price reductions and increased competition.

2. How do biosimilars impact the pricing of original biologic drugs like NDC 00006-0081?
Biosimilars introduce alternative options that typically carry lower prices, prompting branded drugs to reduce prices or adjust market strategies to maintain competitiveness.

3. What policies could influence future prices of NDC 00006-0081?
Potential policies include price caps, increased rebates under Medicare/Medicaid, and value-based pricing models, driven by legislative efforts to contain escalating drug costs.

4. How should pharmaceutical companies prepare for upcoming market changes?
Companies should diversify product portfolios, seek new indications, invest in lifecycle management, and develop competitive biosimilar strategies to stay ahead.

5. Are there emerging therapies that could displace NDC 00006-0081 in its indication?
Emerging therapies, including novel biologics and small-molecule agents, remain under development; their approval could further fragment the market and influence pricing.

Conclusion

The market landscape for NDC 00006-0081 is poised for significant transformation as biosimilar competition and regulatory pressures intensify. Price projections reflect a downward trend, emphasizing the importance for stakeholders to adapt their strategies accordingly. Robust monitoring of regulatory developments, patent timelines, and market dynamics will be essential to optimize investment and operational decisions in this evolving environment.


References

  1. [Insert relevant industry reports and market analyses]
  2. [Cite FDA approval timelines and biosimilar entry data]
  3. [Include recent policy developments relevant to drug pricing]
  4. [Utilize authoritative pricing databases]
  5. [Leverage published academic or industry forecasts]

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