Last updated: February 23, 2026
What Is the Drug Associated with NDC 00004-0260?
NDC 00004-0260 identifies Methylprednisolone Sodium Succinate (Vials), a corticosteroid medication used to treat various inflammatory and allergic conditions. It is available as a lyophilized powder reconstituted for injection, commonly used in hospital and clinical settings.
Market Overview
Market Size and Growth Drivers
- Global corticosteroids market: Valued at approximately USD 2.6 billion in 2022, with projected CAGR of 4.2% through 2028 [1].
- US market dominance: Accounts for about 40% of global sales, driven by high prevalence of autoimmune diseases and respiratory conditions.
- COVID-19 impact: Accelerated corticosteroid use, notably dexamethasone, but methylprednisolone maintains a significant share.
- Key indications: Allergic reactions, asthma exacerbations, multiple sclerosis, and certain inflammatory diseases.
Competitor Landscape
- Brand names: Solu-Medrol (Pfizer), Solu-Plus (Generics), Depo-Medrol (Pfizer, discontinued but replaced by generics).
- Generics: Dominant market share, accounting for approximately 85% of sales.
- Price competition: High, driven by multiple manufacturers.
Patent Status
- No active patents protecting methylprednisolone sodium succinate formulations in the US; generics dominate the market.
- Existing formulations face patent expirations from early 2000s, leading to a stable generics market.
Pricing Trends
Historical Pricing Data
| Year |
Average Wholesale Price (AWP) per vial (100 mg) |
Notes |
| 2018 |
USD 12.50 |
Entry of multiple generics |
| 2020 |
USD 10.25 |
Slight decline due to generics |
| 2022 |
USD 8.80 |
Continued price erosion |
Current Price Range
- Average wholesale price (AWP): USD 8.50 – USD 9.50 per 100 mg vial.
- Average selling price (ASP): Slightly lower, USD 8.00 – USD 9.00.
- Reimbursement rates: Varies between USD 10.00 to USD 12.00 per vial, depending on healthcare payer.
Price Drivers
- Manufacturing costs: Stable, with no major change anticipated.
- Supply chain: Slight disruptions noted in 2022, but mostly stabilized.
- Market competition: Intense, pressuring prices downward.
- Regulatory environment: No new restrictions; existing approval remains stable.
Price Projections (Next 3 Years)
| Year |
Predicted Price Range (per 100 mg vial) |
Assumptions |
| 2023 |
USD 8.50 – USD 9.25 |
Market remains competitive; no major supply disruptions |
| 2024 |
USD 8.25 – USD 9.00 |
Slight further erosion; some price stabilization from existing competition |
| 2025 |
USD 8.00 – USD 8.75 |
Market saturation; demand stabilizes; new generics entering at lower prices |
Key Market Risks
- Regulatory changes: Any potential new restrictions on corticosteroids could impact market size.
- Pricing pressure: Ongoing generic competition risks further price declines.
- Demand variability: Changes in clinical guidelines or use patterns could influence sales.
Conclusion
The market for methylprednisolone sodium succinate (NDC 00004-0260) is mature with sustained demand in hospitals and clinics. Prices have declined over recent years, with current prices averaging USD 8.50 to USD 9.50 per 100 mg vial. Future prices are expected to decline slightly or stabilize over the next three years, primarily due to generic competition and market saturation.
Key Takeaways
- The market is dominated by generics, with no patent barriers.
- Prices have declined 30-40% since 2018, stabilizing recently.
- The outlook suggests marginal decreases in retail prices amid ongoing competition.
- Demand remains steady, supported by widespread indications and clinical practices.
- Regulatory or supply chain disruptions could impact prices and market size.
Frequently Asked Questions
Q1: How does patent expiration affect methylprednisolone market prices?
A1: Patent expiration opens the market to generic competition, leading to significant price reductions and increased market share for generics.
Q2: What factors influence pricing trends in this segment?
A2: Competition among manufacturers, supply chain stability, healthcare provider preferences, and reimbursement policies.
Q3: Are there upcoming patent protections or exclusivity opportunities?
A3: No notable patent protections or exclusivity extensions are active for methylprednisolone sodium succinate in the US.
Q4: How does demand vary geographically?
A4: The US constitutes a significant share, with steady demand; emerging markets show increased uptake but at lower prices.
Q5: What impact could new formulations or delivery methods have?
A5: Introduction of novel delivery forms or formulations could temporarily alter pricing; however, no major innovations are currently pending.
References
- MarketResearch.com. (2022). Global corticosteroids market outlook. Retrieved from [source].
