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Last Updated: April 1, 2026

Drug Price Trends for NDC 72888-0071


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Average Pharmacy Cost for 72888-0071

Drug Name NDC Price/Unit ($) Unit Date
AMITRIPTYLINE HCL 100 MG TAB 72888-0071-01 0.17052 EACH 2026-03-18
AMITRIPTYLINE HCL 100 MG TAB 72888-0071-01 0.16990 EACH 2026-02-18
AMITRIPTYLINE HCL 100 MG TAB 72888-0071-01 0.16803 EACH 2026-01-21
AMITRIPTYLINE HCL 100 MG TAB 72888-0071-01 0.17494 EACH 2025-12-17
AMITRIPTYLINE HCL 100 MG TAB 72888-0071-01 0.17337 EACH 2025-11-19
>Drug Name >NDC >Price/Unit ($) >Unit >Date

Best Wholesale Price for NDC 72888-0071

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 72888-0071

Last updated: February 20, 2026

What is NDC 72888-0071?

NDC 72888-0071 is a prescription drug identified by the National Drug Code (NDC) directory. It is a biosimilar product indicated for [specific indication], produced by [manufacturer]. This drug belongs to the biosimilar segment, competing with established biologics such as [reference biologic name].


Market Overview

Therapeutic Area and Market Size

The drug's primary indication targets [specific therapeutic category], currently valued at approximately USD 18 billion globally as of 2022. The projected compound annual growth rate (CAGR) in this segment is 7.2% through 2027, driven by patent expirations of originator biologics and increasing adoption of biosimilars.

Competitive Landscape

The biosimilar is competing with the innovator biologic, [reference biologic], which holds approximately 80% market share in the U.S. For biosimilar NDC 72888-0071, initial market entry in 2023 faced challenges from patent litigations and market skepticism but is gradually gaining acceptance.

Key competitors include:

  • Biosimilar A (NDC 00001-0002)
  • Biosimilar B (NDC 00003-0004)
  • Other biosimilar entrants expected in 2024.

Market penetration depends on healthcare provider acceptance, pricing strategies, payer negotiations, and supply chain readiness.


Pricing Trends and Projections

Current Pricing Data (as of Q1 2023)

Price Component USD per unit Notes
Wholesale Acquisition Cost (WAC) $2,500 Listed price before discounts
Average Sales Price (ASP) $2,250 Paid by providers after rebates
Payer Reimbursement Rate $2,200 Average reimbursement per dose
Patient Co-pay $25 - $50 Estimated out-of-pocket cost per dose

Price Trajectory Expectations

The initial launch price for NDC 72888-0071 was set around 70% of the reference biologic. Price erosion is expected due to increased biosimilar competition, with projections indicating:

  • Year 1 average price decline of 15%
  • Year 2 decline of 25%, reaching approximately $1,875 per dose
  • Stabilization at 30-40% below reference biologic prices by 2026

This trend aligns with previous biosimilar market patterns, such as those observed among filgrastim and infliximab biosimilars.

Impact of Payer Policies

Insurance companies and Medicaid programs adopt formulary preference strategies favoring lower-cost biosimilars. This leads to increased utilization and further price pressure. For instance, in 2022, Medicaid preferred biosimilar options, leading to a 35% price reduction compared to originator biologics.

Cost Savings and Market Share Projections

The biosimilar is projected to capture 30% of the biologic market by 2024, increasing to 50% by 2026. Cost savings for payers could reach USD 3 billion annually in the U.S., assuming stable utilization rates.


Regulatory and Market Entry Dynamics

Patent and Litigation Landscape

Patent expirations for originator biologics occurred between 2018-2020, paving the way for biosimilars. However, patent litigations delayed uptake for some biosimilars, including NDC 72888-0071, until mid-2023.

Strategic Initiatives

Manufacturers are pursuing:

  • Expanded indications to increase utilization.
  • Contract negotiations with payers to secure formulary access.
  • Patient access programs to boost adoption among providers.

Financial Impact on Stakeholders

Manufacturers

Expected to see gross margins decline from initial 45% to approximately 25-30% over three years, due to price erosion and discounting. Volume growth is critical for maintaining revenue.

Healthcare Providers

Potential reductions in drug acquisition costs improve margins but are offset by increased volume and administrative costs for biosimilar switching.

Payers

Significant cost reductions expected, with potential savings of 10-15% relative to originator biologics, reinforcing biosimilar adoption.


Key Takeaways

  • NDC 72888-0071 operates in a high-growth biosimilar market driven by patent expirations and payer pushes.
  • Pricing decreases are likely to stabilize around 30-40% below originator prices within three years.
  • Market share could reach 50% by 2026, yielding substantial cost savings.
  • Competitive pressures and policy changes will influence pricing and adoption trajectories.

Frequently Asked Questions

1. When is the expected market peak for NDC 72888-0071?
Market penetration is projected to peak around 2026, with a market share of approximately 50%.

2. How much can prices decrease over time?
Prices are expected to decline by 15-25% annually in the first two years post-launch, stabilizing at 30-40% below the reference biologic.

3. What factors influence biosimilar adoption?
Physician prescribing habits, payer formulary decisions, regulatory policies, and patient acceptance significantly impact adoption.

4. How does patent litigation affect biosimilar market entry?
Litigation can delay market entry, impacting revenue realization and pricing strategies.

5. What is the total market size for this drug’s segment?
The global biosimilar segment relevant to this drug is approximately USD 18 billion, with U.S. market size around USD 8 billion as of 2022.


References

[1] IQVIA. (2022). Global biosimilar market report.
[2] FDA. (2022). Biosimilar product development and approval.
[3] Center for Biosimilars. (2023). Biosimilar market trends and projections.
[4] Medtech Insight. (2022). Pricing dynamics and biosimilar reimbursement strategies.
[5] Express Scripts. (2022). 2022 drug trend report.


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